ChangPu YuJin Tang improves Tourette disorder symptoms by modulating amino acid neurotransmitters in IDPN model rats

Aida T, Yoshida J, Nomura M, Tanimura A, Iino Y, Soma M, Bai N, Ito Y, Cui W, Aizawa H, Yanagisawa M, Nagai T, Takata N, Tanaka KF, Takayanagi R, Kano M, Götz M, Hirase H, Tanaka K (2015) Astroglial Glutamate Transporter Deficiency increases synaptic excitability and leads to pathological repetitive behaviors in mice. Neuropsychopharmacol 40:1569–1579. https://doi.org/10.1038/npp.2015.26

Article  CAS  Google Scholar 

Alcantara AA, Chen V, Herring BE, Mendenhall JM, Berlanga ML (2003) Localization of dopamine D2 receptors on cholinergic interneurons of the dorsal striatum and nucleus accumbens of the rat. Brain Res 986:22–29. https://doi.org/10.1016/s0006-8993(03)03165-2

Article  PubMed  CAS  Google Scholar 

Bellocchio EE, Reimer RJ, Fremeau RT, Edwards RH (2000) Uptake of glutamate into synaptic vesicles by an inorganic phosphate transporter. Science 289:957–960. https://doi.org/10.1126/science.289.5481.957

Article  PubMed  CAS  Google Scholar 

Boulland JL, Qureshi T, Seal RP, Rafiki A, Gundersen V, Bergersen LH, Fremeau RT, Edwards RH, Storm Mathisen J, Chaudhry FA (2004) Expression of the vesicular glutamate transporters during development indicates the widespread corelease of multiple neurotransmitters. J Comp Neurol 480:264–280. https://doi.org/10.1002/cne.20354

Article  PubMed  CAS  Google Scholar 

Brander G, Isomura K, Chang Z, Kuja-Halkola R, Almqvist C, Larsson H, Mataix-Cols D, De La Fernández L (2019) Association of Tourette Syndrome and Chronic Tic Disorder with Metabolic and Cardiovascular disorders. Jama Neurol 76:454. https://doi.org/10.1001/jamaneurol.2018.4279

Article  PubMed  PubMed Central  Google Scholar 

Buck SA, Steinkellner T, Aslanoglou D, Villeneuve M, Bhatte SH, Childers VC, Rubin SA, De Miranda BR, O’Leary EI, Neureiter EG, Fogle KJ, Palladino MJ, Logan RW, Glausier JR, Fish KN, Lewis DA, Greenamyre JT, McCabe BD, Cheetham CEJ, Hnasko TS, Freyberg Z (2021) Vesicular glutamate transporter modulates sex differences in dopamine neuron vulnerability to age-related neurodegeneration. Aging Cell 20:e13365. https://doi.org/10.1111/acel.13365

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cadet JL (1989) The iminodipropionitrile (IDPN)-induced dyskinetic syndrome: behavioral and biochemical pharmacology. Neurosci Biobehav Rev 13:39–45. https://doi.org/10.1016/s0149-7634(89)80050-8

Article  PubMed  CAS  Google Scholar 

Cavanna AE, Schrag A, Morley D, Orth M, Robertson MM, Joyce E, Critchley HD, Selai C (2008) The Gilles De La Tourette Syndrome-Quality of Life Scale (GTS-QOL): development and validation. Neurology 71:1410–1416. https://doi.org/10.1212/01.wnl.0000327890.02893.61

Article  PubMed  CAS  Google Scholar 

Cavanna AE, Eddy C, Rickards HE (2009) Cognitive functioning in Tourette syndrome. Discov Med 8:191–195

PubMed  Google Scholar 

Caviston JP, Holzbaur ELF (2009) Huntingtin as an essential integrator of intracellular vesicular trafficking. Trends Cell Biol 19:147–155. https://doi.org/10.1016/j.tcb.2009.01.005

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chen T, Zhu Y, Jia J, Meng H, Xu C, Xian P, Li Z, Tang Z, Wu Y, Liu Y (2022) Mitochondrial transplantation promotes remyelination and long-term locomotion recovery following cerebral ischemia. Mediators Inflamm 2022:1346343. https://doi.org/10.1155/2022/1346343

Article  PubMed  PubMed Central  CAS  Google Scholar 

de Bartolomeis A, Tomasetti C, Iasevoli F (2015) Update on the mechanism of action of Aripiprazole: translational insights into antipsychotic strategies beyond dopamine receptor antagonism. CNS Drugs 29:773–799. https://doi.org/10.1007/s40263-015-0278-3

Article  PubMed  PubMed Central  CAS  Google Scholar 

Di Cristo G (2007) Development of cortical GABAergic circuits and its implications for neurodevelopmental disorders. Clin Genet 72:1–8. https://doi.org/10.1111/j.1399-0004.2007.00822.x

Article  PubMed  Google Scholar 

Fekete S, Egberts K, Preissler T, Wewetzer C, Mehler-Wex C, Romanos M, Gerlach M (2021) Estimation of a preliminary therapeutic reference range for children and adolescents with tic disorders treated with tiapride. Eur J Clin Pharmacol 77:163–170. https://doi.org/10.1007/s00228-020-03000-0

Article  PubMed  CAS  Google Scholar 

Feng P, Li Y, Shang J, Wang Q, Tian W, Wu L, Luo W, Sun Z, Wang N, Shi Z (2022) Effect of self-designed Changpu Yujin Decoction on Synapse Ultrastructure and Synapse-related proteins in Tourette Syndrome rats. Chin J Integr Traditional Western Med 42:1376–1382. https://doi.org/10.7661/j.cjim.20220905.278

Article  Google Scholar 

Feng P, He Y, Sun Z, Wang Z, Shang J, Shi Z (2023) Shi Zhenggang’s experience in treating tic disorder by three stages. Chin Pediatr Integr Traditional Western Med 15:11–14. https://doi.org/10.3969/j.issn.16743865.2023.01.003

Article  Google Scholar 

Gao H (2017) Professor SHI Zhenggang’s experience in treating tourette syndrome in children. J Pediatr Traditional Chin Med 13:11–13. https://doi.org/10.16840/j.issn1673-4297.2017.01.04

Article  Google Scholar 

Gao H, Wang W, Li X, Yang X, Wang J, Shang J, Shi Z (2017) Effect of Changpu Yujin Decoction on monoamine neurotransmitters in tourette syndrome model rats. Pharmacol Clin Chin Materia Med 33:135–138. https://doi.org/10.13412/j.cnki.zyyl.2017.03.039

Article  Google Scholar 

Gao H, Wang W, Shang J, Li X, Yang X, Wang J, Shi Z (2020) Influence of ChangPu YuJin Decoction on DA metabolic enzyme of TS Rat Model. Western J Traditional Chin Med 33:20–22. https://doi.org/10.12174/j.issn.1004-6852.2020.09.06

Article  Google Scholar 

Ghit A, Assal D, Al-Shami AS, Hussein DEE (2021) GABAA receptors: structure, function, pharmacology, and related disorders. J Genetic Eng Biotechnol 19:123. https://doi.org/10.1186/s43141-021-00224-0

Article  Google Scholar 

Govindan RM, Makki MI, Wilson BJ, Behen ME, Chugani HT (2010) Abnormal water diffusivity in corticostriatal projections in children with Tourette syndrome. Hum Brain Mapp 31:1665–1674. https://doi.org/10.1002/hbm.20970

Article  PubMed  PubMed Central  Google Scholar 

Grace AA, Floresco SB, Goto Y, Lodge DJ (2007) Regulation of firing of dopaminergic neurons and control of goal-directed behaviors. Trends Neurosci 30:220–227. https://doi.org/10.1016/j.tins.2007.03.003

Article  PubMed  CAS  Google Scholar 

He F, Zheng Y, Cheng Y, Huang H (2014) Study about the relationship between efficacy and serum level of BDNF in patients with Tourette syndrome. J Psychiatry 27:248–250. https://doi.org/10.3969/j.issn.1009-7201.2014.04.003

Article  Google Scholar 

Heise KF, Steven B, Liuzzi G, Thomalla G, Jonas M, Muller-Vahl K, Sauseng P, Munchau A, Gerloff C, Hummel FC (2010) Altered modulation of intracortical excitability during movement preparation in Gilles De La Tourette syndrome. Brain 133:580–590. https://doi.org/10.1093/brain/awp299

Article  PubMed  Google Scholar 

Hensch TK (2005) Critical period plasticity in local cortical circuits. Nat Rev Neurosci 6:877–888. https://doi.org/10.1038/nrn1787

Article  PubMed  CAS  Google Scholar 

Hnasko TS, Chuhma N, Zhang H, Goh GY, Sulzer D, Palmiter RD, Rayport S, Edwards RH (2010) Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron 65:643–656. https://doi.org/10.1016/j.neuron.2010.02.012

Article  PubMed  PubMed Central  CAS  Google Scholar 

Hongyan L, Zhenyang S, Chunyan W, Qingqing P (2017) Lipopolysaccharide aggravated DOI-induced Tourette syndrome: elaboration for recurrence of Tourette syndrome. Metab Brain Dis 32:1929–1934. https://doi.org/10.1007/s11011-017-0084-3

Article  PubMed  CAS  Google Scholar 

Jafari F, Abbasi P, Rahmati M, Hodhodi T, Kazeminia M (2022) Systematic review and Meta-analysis of Tourette Syndrome Prevalence; 1986 to 2022. Pediatr Neurol 137:6–16. https://doi.org/10.1016/j.pediatrneurol.2022.08.010

Article  PubMed  Google Scholar 

Jiménez-Jiménez FJ, Alonso-Navarro H, García-Martín E, Agúndez JAG (2020) Sleep disorders in tourette syndrome. Sleep Med Rev 53:101335. https://doi.org/10.1016/j.smrv.2020.101335

Article  PubMed  Google Scholar 

Comments (0)

No login
gif