Alvarez AM, DeOcesano-Pereira C, Teixeira C, Moreira V (2020) IL-1beta and TNF-alpha modulation of proliferated and committed myoblasts: IL-6 and COX-2-derived prostaglandins as key actors in the mechanisms involved. Cells 9:9
Bartelt A, Widenmaier SB, Schlein C et al (2018) Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity. Nat Med 24(3):292–303
Article CAS PubMed PubMed Central Google Scholar
Berg DT, Gupta A, Richardson MA et al (2007) Negative regulation of inducible nitric-oxide synthase expression mediated through transforming growth factor-beta-dependent modulation of transcription factor TCF11. J Biol Chem 282(51):36837–36844
Article CAS PubMed Google Scholar
Chamorro Á, Meisel A, Planas AM et al (2012) The immunology of acute stroke. Nat Rev Neurol 8(7):401–410
Article CAS PubMed Google Scholar
Che D, Zhang S, Jing Z et al (2017) Macrophages induce EMT to promote invasion of lung cancer cells through the IL-6-mediated COX-2/PGE2/beta-catenin signalling pathway. Mol Immunol 90:197–210
Article CAS PubMed Google Scholar
Danaher P, Warren S, Dennis L et al (2017) Gene expression markers of tumor infiltrating leukocytes. J Immunother Cancer 5:18
Article PubMed PubMed Central Google Scholar
Franke M, Bieber M, Kraft P et al (2021) The NLRP3 inflammasome drives inflammation in ischemia/reperfusion injury after transient middle cerebral artery occlusion in mice. Brain Behav Immun 92:223–233
Gu C, Yang J, Luo Y et al (2021) ZNRF2 attenuates focal cerebral ischemia/reperfusion injury in rats by inhibiting mTORC1-mediated autophagy. Exp Neurol 342:113759
Article CAS PubMed Google Scholar
Han W, Ming M, Zhao R et al (2012) Nrf1 CNC-bZIP protein promotes cell survival and nucleotide excision repair through maintaining glutathione homeostasis. J Biol Chem 287(22):18788–18795
Article CAS PubMed PubMed Central Google Scholar
Hertel M, Braun S, Durka S, Alzheimer C, Werner S (2002) Upregulation and activation of the Nrf-1 transcription factor in the lesioned hippocampus. Eur J Neurosci 15(10):1707–1711
Kwong M, Kan YW, Chan JY (1999) The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts. J Biol Chem 274(52):37491–37498
Article CAS PubMed Google Scholar
Lambertsen KL, Biber K, Finsen B (2012) Inflammatory cytokines in experimental and human stroke. J Cereb Blood Flow Metab 32(9):1677–1698
Article CAS PubMed PubMed Central Google Scholar
Lee CS, Lee C, Hu T et al (2011) Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration. Proc Natl Acad Sci U S A 108(20):8408–8413
Article CAS PubMed PubMed Central Google Scholar
Li W, Wu S, Hickey RW et al (2008) Neuronal cyclooxygenase-2 activity and prostaglandins PGE2, PGD2, and PGF2 alpha exacerbate hypoxic neuronal injury in neuron-enriched primary culture. Neurochem Res 33(3):490–499
Article CAS PubMed Google Scholar
Liu Z, Wang H, Hou Y et al (2021) CNC-bZIP protein NFE2L1 regulates osteoclast differentiation in antioxidant-dependent and independent manners. Redox Biol 48:102180
Article CAS PubMed PubMed Central Google Scholar
Liu X, Jin S, Hu S et al (2022) Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma. Nat Commun 13(1):1158
Article CAS PubMed PubMed Central Google Scholar
Longa EZ, Weinstein PR, Carlson S, Cummins R (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20(1):84–91
Article CAS PubMed Google Scholar
Lund BC, Abrams TE, Gravely AA (2011) Rebuttal to Gravely et al. Validity of PTSD diagnoses in VA administrative data: comparison of VA administrative PTSD diagnoses to self-reported PTSD Checklist scores. J Rehabil Res Dev 48(1):21–30
Murphy P, Kolstø A-B (2000) Expression of the bZIP transcription factor TCF11 and its potential dimerization partners during development. Mech Dev 97(1–2):141–148
Article CAS PubMed Google Scholar
Myhrstad MC, Husberg C, Murphy P et al (2001) TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter. Biochim Biophys Acta 1517(2):212–219
Article CAS PubMed Google Scholar
Nakano R, Kitanaka T, Namba S et al (2020) Non-transcriptional and translational function of canonical NF-kappaB signaling in activating ERK1/2 in IL-1beta-induced COX-2 expression in synovial fibroblasts. Front Immunol 11:579266
Article CAS PubMed PubMed Central Google Scholar
Neeb L, Hellen P, Boehnke C et al (2011) IL-1beta stimulates COX-2 dependent PGE2 synthesis and CGRP release in rat trigeminal ganglia cells. PLoS ONE 6(3):e17360
Article CAS PubMed PubMed Central Google Scholar
Novotny V, Prieschl EE, Csonga R, Fabjani G, Baumruker T (1998) Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 component at the TNF alpha promoter in stimulated mast cells. Nucleic Acids Res 26(23):5480–5485
Article CAS PubMed PubMed Central Google Scholar
Ohtsuji M, Katsuoka F, Kobayashi A et al (2008) Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes. J Biol Chem 283(48):33554–33562
Article CAS PubMed PubMed Central Google Scholar
Peng Z, Li M, Tan X et al (2020) miR-211-5p alleviates focal cerebral ischemia-reperfusion injury in rats by down-regulating the expression of COX2. Biochem Pharmacol 177:113983
Article CAS PubMed Google Scholar
Prieschl EE, Novotny V, Csonga R et al (1998) A novel splice variant of the transcription factor Nrf1 interacts with the TNF promoter and stimulates transcription. Nucleic Acids Res 26(10):2291–2297
Article CAS PubMed PubMed Central Google Scholar
Ren S, Hou Y, Zuo Z et al (2020) Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice. Food Chem Toxicol 146:111836
Article CAS PubMed Google Scholar
Roth S, Singh V, Tiedt S et al (2018) Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke. Sci Transl Med 10(432):eaao1313
Rushmore TH, Morton MR, Pickett CB (1991) The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem 266(18):11632–11639
Article CAS PubMed Google Scholar
Shivdasani RA, Orkin SH (1995) Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2. Proc Natl Acad Sci U S A 92(19):8690–8694
Comments (0)