Babakhanzadeh E, Nazari M, Ghasemifar S, Khodadadian A. Some of the Factors Involved in Male Infertility: A Prospective Review. Int J Gen Med. 2020;13:29–41. https://doi.org/10.2147/IJGM.S241099.
Article PubMed PubMed Central CAS Google Scholar
Rolfes V, Bittner U, Gerhards H, Krussel JS, Fehm T, Ranisch R, Fangerau H. Artificial Intelligence in Reproductive Medicine - An Ethical Perspective. Geburtshilfe Frauenheilkd. 2023;83:106–15. https://doi.org/10.1055/a-1866-2792.
Article PubMed PubMed Central Google Scholar
Sharma U. Paternal Contributions to Offspring Health: Role of Sperm Small RNAs in Intergenerational Transmission of Epigenetic Information. Front Cell Dev Biol. 2019;7:215. https://doi.org/10.3389/fcell.2019.00215.
Article PubMed PubMed Central Google Scholar
Zhu X, Ma X, Zhao S, Cao Z. DLX6-AS1 accelerates cell proliferation through regulating miR-497-5p/SNCG pathway in prostate cancer. Environ Toxicol. 2021;36:308–19. https://doi.org/10.1002/tox.23036.
Article PubMed CAS Google Scholar
Krawetz SA, Kruger A, Lalancette C, Tagett R, Anton E, Draghici S, Diamond MP. A survey of small RNAs in human sperm. Hum Reprod. 2011;26:3401–12. https://doi.org/10.1093/humrep/der329.
Article PubMed PubMed Central CAS Google Scholar
Salas-Huetos A, James ER, Aston KI, Carrell DT, Jenkins TG, Yeste M. The role of miRNAs in male human reproduction: a systematic review. Andrology. 2020;8:7–26. https://doi.org/10.1111/andr.12714.
Article PubMed CAS Google Scholar
Abu-Halima M, Becker LS, Al Smadi MA, Abdul-Khaliq H, Raeschle M, Meese E. Sperm Motility Annotated Genes: Are They Associated with Impaired Fecundity? Cells. 2023;12:1239. https://doi.org/10.3390/cells12091239.
Article PubMed PubMed Central CAS Google Scholar
Becker LS, Al Smadi MA, Raeschle M, Rishik S, Abdul-Khaliq H, Meese E, Abu-Halima M. Proteomic Landscape of Human Sperm in Patients with Different Spermatogenic Impairments. Cells. 2023;12(7):1017. https://doi.org/10.3390/cells12071017.
Article PubMed PubMed Central CAS Google Scholar
Abu-Halima M, Becker LS, Ayesh BM, Meese E. MicroRNA-targeting in male infertility: Sperm microRNA-19a/b-3p and its spermatogenesis related transcripts content in men with oligoasthenozoospermia. Front Cell Dev Biol. 2022;10:973849. https://doi.org/10.3389/fcell.2022.973849.
Article PubMed PubMed Central Google Scholar
Cappallo-Obermann H, Schulze W, Jastrow H, Baukloh V, Spiess AN. Highly purified spermatozoal RNA obtained by a novel method indicates an unusual 28S/18S rRNA ratio and suggests impaired ribosome assembly. Mol Hum Reprod. 2011;17:669–78. https://doi.org/10.1093/molehr/gar037.
Article PubMed CAS Google Scholar
Abu-Halima M, Hammadeh M, Schmitt J, Leidinger P, Keller A, Meese E, Backes C. Altered microRNA expression profiles of human spermatozoa in patients with different spermatogenic impairments. Fertil Steril. 2013;99:1249-1255 e1216. https://doi.org/10.1016/j.fertnstert.2012.11.054.
Article PubMed CAS Google Scholar
Salas-Huetos A, Blanco J, Vidal F, Mercader JM, Garrido N, Anton E. New insights into the expression profile and function of micro-ribonucleic acid in human spermatozoa. Fertil Steril. 2014;102:213-222 e214. https://doi.org/10.1016/j.fertnstert.2014.03.040.
Article PubMed CAS Google Scholar
Cappallo-Obermann H, Spiess AN. Comment on “Absence of sperm RNA elements correlates with idiopathic male infertility”. Sci Transl Med 2016, 8:353 https://doi.org/10.1126/scitranslmed.aaf2396.
Krawetz SA. Paternal contribution: new insights and future challenges. Nat Rev Genet. 2005;6:633–42. https://doi.org/10.1038/nrg1654.
Article PubMed CAS Google Scholar
Pessot CA, Brito M, Figueroa J, Concha II, Yanez A, Burzio LO. Presence of RNA in the sperm nucleus. Biochem Biophys Res Commun. 1989;158:272–8. https://doi.org/10.1016/s0006-291x(89)80208-6.
Article PubMed CAS Google Scholar
Jodar M, Selvaraju S, Sendler E, Diamond MP, Krawetz SA, Reproductive Medicine N. The presence, role and clinical use of spermatozoal RNAs. Hum Reprod Update. 2013;19:604–24. https://doi.org/10.1093/humupd/dmt031.
Article PubMed PubMed Central CAS Google Scholar
Fehlmann T, Kern F, Laham O, Backes C, Solomon J, Hirsch P, Volz C, Muller R, Keller A. miRMaster 2.0: multi-species non-coding RNA sequencing analyses at scale. Nucleic Acids Res. 2021;49:397–408. https://doi.org/10.1093/nar/gkab268.
Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 2009;10:R25. https://doi.org/10.1186/gb-2009-10-3-r25.
Article PubMed PubMed Central CAS Google Scholar
Lewis SE. Is sperm evaluation useful in predicting human fertility? Reproduction. 2007;134:31–40. https://doi.org/10.1530/REP-07-0152.
Article PubMed CAS Google Scholar
Jan SZ, Vormer TL, Jongejan A, Roling MD, Silber SJ, de Rooij DG, Hamer G, Repping S, van Pelt AMM. Unraveling transcriptome dynamics in human spermatogenesis. Development. 2017;144:3659–73. https://doi.org/10.1242/dev.152413.
Article PubMed PubMed Central CAS Google Scholar
Bao J, Bedford MT. Epigenetic regulation of the histone-to-protamine transition during spermiogenesis. Reproduction. 2016;151:R55-70. https://doi.org/10.1530/REP-15-0562.
Article PubMed PubMed Central CAS Google Scholar
Linn E, Ghanem L, Bhakta H, Greer C, Avella M. Genes Regulating Spermatogenesis and Sperm Function Associated With Rare Disorders. Front Cell Dev Biol. 2021;9:634536. https://doi.org/10.3389/fcell.2021.634536.
Article PubMed PubMed Central Google Scholar
Joshi M, Rajender S. Long non-coding RNAs (lncRNAs) in spermatogenesis and male infertility. Reprod Biol Endocrinol. 2020;18:103. https://doi.org/10.1186/s12958-020-00660-6.
Article PubMed PubMed Central CAS Google Scholar
Frias-Lasserre D, Villagra CA. The Importance of ncRNAs as Epigenetic Mechanisms in Phenotypic Variation and Organic Evolution. Front Microbiol. 2017;8:2483. https://doi.org/10.3389/fmicb.2017.02483.
Article PubMed PubMed Central Google Scholar
Wang X, Yang C, Guo F, Zhang Y, Ju Z, Jiang Q, Zhao X, Liu Y, Zhao H, Wang J, et al. Integrated analysis of mRNAs and long noncoding RNAs in the semen from Holstein bulls with high and low sperm motility. Sci Rep. 2019;9:2092. https://doi.org/10.1038/s41598-018-38462-x.
Article PubMed PubMed Central CAS Google Scholar
Hong Y, Wang C, Fu Z, Liang H, Zhang S, Lu M, Sun W, Ye C, Zhang CY, Zen K, et al. Systematic characterization of seminal plasma piRNAs as molecular biomarkers for male infertility. Sci Rep. 2016;6:24229. https://doi.org/10.1038/srep24229.
Article PubMed PubMed Central CAS Google Scholar
Hong Y, Wu Y, Zhang J, Yu C, Shen L, Chen H, Chen L, Zhou X, Gao F. Decreased piRNAs in Infertile Semen Are Related to Downregulation of Sperm MitoPLD Expression. Front Endocrinol (Lausanne). 2021;12:696121. https://doi.org/10.3389/fendo.2021.696121.
Vojtech L, Woo S, Hughes S, Levy C, Ballweber L, Sauteraud RP, Strobl J, Westerberg K, Gottardo R, Tewari M, et al. Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions. Nucleic Acids Res. 2014;42:7290–304.
Comments (0)