Potential application of [18F]AlF-PSMA-11 PET/CT in radioiodine refractory thyroid carcinoma

Lim H, Devesa SS, Sosa JA, Check D, Kitahara CM. Trends in thyroid cancer incidence and mortality in the United States, 1974–2013. JAMA. 2017;317:1338–48.

Article  PubMed  PubMed Central  Google Scholar 

Paschke R, Lincke T, Müller SP, Kreissl MC, Dralle H, Fassnacht M. The treatment of well-differentiated thyroid carcinoma. Dtsch Ärztebl Int. 2015;112:452–8.

PubMed  PubMed Central  Google Scholar 

Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: The American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid. 2016;26:1–133.

Article  PubMed  PubMed Central  Google Scholar 

Liu J, Liu Y, Lin Y, Liang J. Radioactive Iodine-refractory differentiated thyroid cancer and redifferentiation therapy. Endocrinol Metab. 2019;34:215–25.

Article  CAS  Google Scholar 

Cabanillas ME, Patel A, Danysh BP, Dadu R, Kopetz S, Falchook G. BRAF inhibitors: experience in thyroid cancer and general review of toxicity. Horm Cancer. 2015;6:21–36.

Article  CAS  PubMed  Google Scholar 

Babu G, Kainickal CT. Update on the systemic management of radioactive iodine refractory differentiated thyroid cancer (review). Mol Clin Oncol. 2021;14:35.

Article  CAS  PubMed  Google Scholar 

Durante C, Haddy N, Baudin E, Leboulleux S, Hartl D, Travagli JP, et al. Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioiodine therapy. J Clin Endocrinol Metab. 2006;91:2892–9.

Article  CAS  PubMed  Google Scholar 

Worden F. Treatment strategies for radioactive iodine-refractory differentiated thyroid cancer. Ther Adv Med Oncol. 2014;6:267–79.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maurer T, Eiber M, Schwaiger M, Gschwend JE. Current use of PSMA-PET in prostate cancer management. Nat Rev Urol. 2016;13:226–35.

Article  CAS  PubMed  Google Scholar 

Bouchelouche K, Choyke PL. Advances in prostate-specific membrane antigen PET of prostate cancer. Curr Opin Oncol. 2018;30:189–96.

Article  PubMed  PubMed Central  Google Scholar 

Farolfi A, Calderoni L, Mattana F, Mei R, Telo S, Fanti S, et al. Current and emerging clinical applications of PSMA PET diagnostic imaging for prostate cancer. J Nucl Med Off Publ Soc Nucl Med. 2021;62:596–604.

CAS  Google Scholar 

Hofman MS, Violet J, Hicks RJ, Ferdinandus J, Thang SP, Akhurst T, et al. [177Lu]-PSMA-617 radionuclide treatment in patients with metastatic castration-resistant prostate cancer (LuPSMA trial): a single-centre, single-arm, phase 2 study. Lancet Oncol. 2018;19:825–33.

Article  CAS  PubMed  Google Scholar 

Kinoshita Y, Kuratsukuri K, Landas S, Imaida K, Rovito PM, Wang CY, et al. Expression of prostate-specific membrane antigen in normal and malignant human tissues. World J Surg. 2006;30:628–36.

Article  PubMed  Google Scholar 

Silver DA, Pellicer I, Fair WR, Heston WD, Cordon-Cardo C. Prostate-specific membrane antigen expression in normal and malignant human tissues. Clin Cancer Res Off J Am Assoc Cancer Res. 1997;3:81–5.

CAS  Google Scholar 

Heitkötter B, Steinestel K, Trautmann M, Grünewald I, Barth P, Gevensleben H, et al. Neovascular PSMA expression is a common feature in malignant neoplasms of the thyroid. Oncotarget. 2018;9:9867–74.

Article  PubMed  PubMed Central  Google Scholar 

Haffner MC, Kronberger IE, Ross JS, Sheehan CE, Zitt M, Mühlmann G, et al. Prostate-specific membrane antigen expression in the neovasculature of gastric and colorectal cancers. Hum Pathol. 2009;40:1754–61.

Article  CAS  PubMed  Google Scholar 

Chang SS, Reuter VE, Heston WD, Bander NH, Grauer LS, Gaudin PB. Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature. Cancer Res. 1999;59:3192–8.

CAS  PubMed  Google Scholar 

Sager S, Vatankulu B, Uslu L, Sönmezoglu K. Incidental detection of follicular thyroid carcinoma in 68Ga-PSMA PET/CT imaging. J Nucl Med Technol. 2016;44:199–200.

Article  PubMed  Google Scholar 

Tang K, Wang Z, Lin J, Zheng X. Hürthle cell thyroid adenoma showing avid uptake on 18F-PSMA-1007 PET/CT. Clin Nucl Med. 2020;45:223–4.

Article  PubMed  Google Scholar 

Ciappuccini R, Edet-Sanson A, Saguet-Rysanek V, Gauthé M, Bardet S. Thyroid incidentaloma on 18F-fluorocholine PET/CT and 68Ga-PSMA PET/CT revealing a medullary thyroid carcinoma. Clin Nucl Med. 2019;44:663–5.

Article  PubMed  Google Scholar 

Derlin T, Kreipe H-H, Schumacher U, Soudah B. PSMA expression in tumor neovasculature endothelial cells of follicular thyroid adenoma as identified by molecular imaging using 68Ga-PSMA ligand PET/CT. Clin Nucl Med. 2017;42:e173–4.

Article  PubMed  Google Scholar 

Damle NA, Bal C, Singh TP, Gupta R, Reddy S, Kumar R, et al. Anaplastic thyroid carcinoma on 68 Ga-PSMA PET/CT: opening new frontiers. Eur J Nucl Med Mol Imaging. 2018;45:667–8.

Article  PubMed  Google Scholar 

Taywade SK, Damle NA, Bal C. PSMA expression in papillary thyroid carcinoma: opening a new horizon in management of thyroid cancer? Clin Nucl Med. 2016;41:e263-265.

Article  PubMed  Google Scholar 

Verburg FA, Krohn T, Heinzel A, Mottaghy FM, Behrendt FF. First evidence of PSMA expression in differentiated thyroid cancer using [68Ga]PSMA-HBED-CC PET/CT. Eur J Nucl Med Mol Imaging. 2015;42:1622–3.

Article  PubMed  Google Scholar 

Moore M, Panjwani S, Mathew R, Crowley M, Liu Y-F, Aronova A, et al. Well-differentiated thyroid cancer neovasculature expresses prostate-specific membrane antigen-a possible novel therapeutic target. Endocr Pathol. 2017;28:339–44.

Article  CAS  PubMed  Google Scholar 

Sollini M, di Tommaso L, Kirienko M, Piombo C, Erreni M, Lania AG, et al. PSMA expression level predicts differentiated thyroid cancer aggressiveness and patient outcome. EJNMMI Res. 2019;9:93.

Article  PubMed  PubMed Central  Google Scholar 

Ryu YJ, Lim SY, Na YM, Park MH, Kwon SY, Lee JS. Prostate-specific membrane antigen expression predicts recurrence of papillary thyroid carcinoma after total thyroidectomy. BMC Cancer. 2022;22:1278.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lütje S, Gomez B, Cohnen J, Umutlu L, Gotthardt M, Poeppel TD, et al. Imaging of prostate-specific membrane antigen expression in metastatic differentiated thyroid cancer using 68Ga-HBED-CC-PSMA PET/CT. Clin Nucl Med. 2017;42:20–5.

Article  PubMed  Google Scholar 

Lawhn-Heath C, Yom SS, Liu C, Villanueva-Meyer JE, Aslam M, Smith R, et al. Gallium-68 prostate-specific membrane antigen ([68Ga]Ga-PSMA-11) PET for imaging of thyroid cancer: a feasibility study. EJNMMI Res. 2020;10:128.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Verma P, Malhotra G, Meshram V, Chandak A, Sonavane S, Lila AR, et al. Prostate-specific membrane antigen expression in patients with differentiated thyroid cancer with thyroglobulin elevation and negative iodine scintigraphy using 68Ga-PSMA-HBED-CC PET/CT. Clin Nucl Med. 2021;46:e406–9.

Article  PubMed  Google Scholar 

Verma P, Malhotra G, Agrawal R, Sonavane S, Meshram V, Asopa RV. Evidence of prostate-specific membrane antigen expression in metastatic differentiated thyroid cancer using 68Ga-PSMA-HBED-CC PET/CT. Clin Nucl Med. 2018;43:e265–8.

Article  PubMed  Google Scholar 

Santhanam P, Russell J, Rooper LM, Ladenson PW, Pomper MG, Rowe SP. The prostate-specific membrane antigen (PSMA)-targeted radiotracer 18F-DCFPyL detects tumor neovasculature in metastatic, advanced, radioiodine-refractory, differentiated thyroid cancer. Med Oncol Northwood Lond Engl. 2020;37:98.

Article  CAS 

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