COL1A1, mediated by m6A methylation of METTL3, facilitates oral squamous cell carcinoma cell growth and metastasis

Bugshan, A. and I. Farooq, Oral squamous cell carcinoma: metastasis, potentially associated malignant disorders, etiology and recent advancements in diagnosis. F1000Res. 2020;9:229.

Chamoli A, et al. Overview of oral cavity squamous cell carcinoma: risk factors, mechanisms, and diagnostics. Oral Oncol. 2021;121:105451.

Article  PubMed  Google Scholar 

Howard A, Agrawal N, Gooi Z. Lip and oral cavity squamous cell carcinoma. Hematol Oncol Clin North Am. 2021;35(5):895–911.

Article  PubMed  Google Scholar 

Jiang M, Li B. STAT3 and its targeting inhibitors in oral squamous cell carcinoma. Cells. 2022;11(19):3131.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pollaers K, et al. The economic burden of oral squamous cell carcinoma in Australia. J Oral Pathol Med. 2019;48(7):588–94.

Article  PubMed  Google Scholar 

Panarese I, et al. Oral and Oropharyngeal squamous cell carcinoma: prognostic and predictive parameters in the etiopathogenetic route. Expert Rev Anticancer Ther. 2019;19(2):105–19.

Article  CAS  PubMed  Google Scholar 

Chen SH, Li D, Xu C. Downregulation of Col1a1 induces differentiation in mouse spermatogonia. Asian J Androl. 2012;14(6):842–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Turecek C, et al. Collagen cross-linking influences osteoblastic differentiation. Calcif Tissue Int. 2008;82(5):392–400.

Article  CAS  PubMed  Google Scholar 

Li X, et al. COL1A1: A novel oncogenic gene and therapeutic target in malignancies. Pathol Res Pract. 2022;236: 154013.

Article  CAS  PubMed  Google Scholar 

Ma HP, et al. Collagen 1A1 (COL1A1) is a reliable biomarker and putative therapeutic target for hepatocellular carcinogenesis and metastasis. Cancers (Basel). 2019;11(6):786.

Article  CAS  PubMed  Google Scholar 

Liu J, et al. Collagen 1A1 (COL1A1) promotes metastasis of breast cancer and is a potential therapeutic target. Discov Med. 2018;25(139):211–23.

CAS  PubMed  Google Scholar 

Wang Q, Yu J. MiR-129-5p suppresses gastric cancer cell invasion and proliferation by inhibiting COL1A1. Biochem Cell Biol. 2018;96(1):19–25.

Article  CAS  PubMed  Google Scholar 

Cui Z, et al. Construction of the miRNA-mRNA regulatory network and analysis of hub genes in oral squamous cell carcinoma. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022;166(3):280–9.

Article  PubMed  Google Scholar 

Peng Y, et al. Integration of transcriptomics and metabolomics reveals a novel gene signature guided by FN1 associated with immune response in oral squamous cell carcinoma tumorigenesis. J Cancer Res Clin Oncol. 2023;149(9):6097–113.

Article  CAS  PubMed  Google Scholar 

Garbo S, Zwergel C, Battistelli C. m6A RNA methylation and beyond - the epigenetic machinery and potential treatment options. Drug Discov Today. 2021;26(11):2559–74.

Article  CAS  PubMed  Google Scholar 

Sun Y, et al. N6-methyladenosine (m6A) methylation in kidney diseases: mechanisms and therapeutic potential. Biochim Biophys Acta Gene Regul Mech. 2023;1866(4):194967.

Article  CAS  PubMed  Google Scholar 

Chen L, et al. METTL3-mediated m6A modification stabilizes TERRA and maintains telomere stability. Nucleic Acids Res. 2022;50(20):11619–34.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wen L, et al. The m6A methyltransferase METTL3 promotes LPS-induced microglia inflammation through TRAF6/NF-kappaB pathway. NeuroReport. 2022;33(6):243–51.

Article  CAS  PubMed  Google Scholar 

Liang H, Fang C, Zhang L. Methyltransferase-like 3 facilitates the stem cell properties of esophageal cancer by upregulating patched homolog 1 via N6-methyladenosine methylation. Am J Physiol Cell Physiol. 2023;325(3):C770–9.

Article  CAS  PubMed  Google Scholar 

Xu Y, et al. METTL3 promotes proliferation and migration of colorectal cancer cells by increasing SNHG1 stability. Mol Med Rep. 2023. https://doi.org/10.3892/mmr.2023.13104.

Article  PubMed  PubMed Central  Google Scholar 

Xu L, et al. m(6)A methyltransferase METTL3 promotes oral squamous cell carcinoma progression through enhancement of IGF2BP2-mediated SLC7A11 mRNA stability. Am J Cancer Res. 2021;11(11):5282–98.

CAS  PubMed  PubMed Central  Google Scholar 

Wu S, et al. Overexpression of methyltransferase-like 3 and 14 in oral squamous cell carcinoma. J Oral Pathol Med. 2022;51(2):134–45.

Article  CAS  PubMed  Google Scholar 

Keshani F, et al. Screening of oral squamous cell carcinoma by serum changes: a systematic review and meta-analysis. Dent Res J (Isfahan). 2021;18:88.

Article  PubMed  Google Scholar 

Li H, et al. The p38 signaling pathway mediates the TGF-beta1-induced increase in type I collagen deposition in human granulosa cells. FASEB J. 2020;34(11):15591–604.

Article  CAS  PubMed  Google Scholar 

Alpogan O. Association of osteogenesis imperfecta and glaucoma: case report. Ophthalmic Genet. 2023;44(5):475–9.

Article  CAS  PubMed  Google Scholar 

Pan TT, et al. A novel mutation in COL1A1 causing osteogenesis imperfecta/hearing loss. Braz J Otorhinolaryngol. 2023;89(5): 101312.

Article  PubMed  PubMed Central  Google Scholar 

Peris P, et al. Collagen type Ialpha1 gene polymorphism in idiopathic osteoporosis in men. Rheumatology (Oxford). 2000;39(11):1222–5.

Article  CAS  PubMed  Google Scholar 

Huang X, et al. LncRNA FBXL19-AS1 promotes proliferation and metastasis of cervical cancer through upregulating COL1A1 as a sponge of miR-193a-5p. J Biol Res (Thessalon). 2021;28(1):20.

Article  CAS  PubMed  Google Scholar 

Chen X, et al. CircRNA circ_0004370 promotes cell proliferation, migration, and invasion and inhibits cell apoptosis of esophageal cancer via miR-1301-3p/COL1A1 axis. Open Med (Wars). 2021;16(1):104–16.

Article  PubMed  Google Scholar 

He B, et al. MiR-133a-3p inhibits oral squamous cell carcinoma (Oscc) proliferation and invasion by suppressing COL1A1. J Cell Biochem. 2018;119(1):338–46.

Article  CAS  PubMed  Google Scholar 

Zhao Y, Yao R. Long non-coding RNA HOXA-AS3 promotes cell proliferation of oral squamous cell carcinoma through sponging microRNA miR-218-5p. Bioengineered. 2021;12(1):8724–37.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Han YK, et al. Promoter methylation of cancer stem cell surface markers as an epigenetic biomarker for prognosis of oral squamous cell carcinoma. Int J Mol Sci. 2022;23(23):14624.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang X, et al. The role of m6A modification in the biological functions and diseases. Signal Transduct Target Ther. 2021;6(1):74.

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