Kim H.Y., Kim C.J., Rho T.H., Youn H.J., Jin S.W., Rhim H.Y., Park J.W., Jeon H.K., Chae J.S., Kim J.H., Hong S.J., Choi K.B. 1999. Transesophageal echocardiographic detection of thoracic aortic plaque could noninvasively predict significant obstructive coronary artery disease. Korean J. Intern. Med. 14 (2), 20‒26.
Article CAS PubMed PubMed Central Google Scholar
Hung A., Zafar M., Mukherjee S., Tranquilli M., Scoutt L.M., Elefteriades J.A. 2012. Carotid intima-media thickness provides evidence that ascending aortic aneurysm protects against systemic atherosclerosis. Cardiology. 123 (2), 71–77.
Achneck H., Modi B., Shaw C., Rizzo J., Albornoz G., Fusco D., Elefteriades J. 2005. Ascending thoracic aneurysms are associated with decreased systemic atherosclerosis. Chest. 128 (3), 1580–1586.
Curtis A., Smith T., Ziganshin B.A., Elefteriades J.A. 2015. Ascending aortic proaneurysmal genetic mutations with antiatherogenic effects. Int. J. Angiol. 24 (3), 189–197.
Article PubMed PubMed Central Google Scholar
Prakash S.K., LeMaire S.A., Guo D.C., Russell L., Regalado E.S., Golabbakhsh H., Johnson R.J., Safi H.J., Estrera A.L., Coselli J.S., Bray M.S., Leal S.M., Milewicz D.M., Belmont J.W. 2010. Rare copy number variants disrupt genes regulating vascular smooth muscle cell adhesion and contractility in sporadic thoracic aortic aneurysms and dissections. Am. J. Hum. Genet. 87 (6), 743‒756.
Article CAS PubMed PubMed Central Google Scholar
Sleptsov A.A., Nazarenko M.S., Lebedev I.N., Skryabin N.A., Frolov A.V., Popov V.A., Barbarash O.L., Barbarash L.S., Puzyrev V.P. 2014. Somatic genome variations in vascular tissues and peripheral blood leukocytes in patients with atherosclerosis. Russ. J. Genet. 50 (8), 870–878.
Prakash S., Kuang S.Q., GenTAC Registry Investigators, Regalado E., Guo D., Milewicz D. 2016. Recurrent rare genomic copy number variants and bicuspid aortic valve are enriched in early onset thoracic aortic aneurysms and dissections. PLoS One. 11 (4), e0153543.
Article PubMed PubMed Central Google Scholar
Overwater E., Marsili L., Baars M.J.H., Baas A.F., van de Beek I., Dulfer E., van Hagen J.M., Hilhorst-Hofstee Y., Kempers M., Krapels I.P., Menke L.A., Verhagen J.M.A., Yeung K.K., Zwijnenburg P.J.G., Groenink M., van Rijn P., Weiss M.M., Voorhoeve E., van Tintelen J.P., Houweling A.C., Maugeri A. 2018. Results of next-generation sequencing gene panel diagnostics including copy-number variation analysis in 810 patients suspected of heritable thoracic aortic disorders. Hum. Mutat. 39 (9), 1173–1192.
Article CAS PubMed PubMed Central Google Scholar
Ostberg N.P., Zafar M.A., Ziganshin B.A., Elefteriades J.A. 2020. The genetics of thoracic aortic aneurysms and dissection: a clinical perspective. Biomolecules. 10 (2), 182.
Article CAS PubMed PubMed Central Google Scholar
Nazarenko M.S., Markov A.V., Lebedev I.N., Freidin M.B., Sleptcov A.A., Koroleva I.A., Frolov A.V., Popov V.A., Barbarash O.L., Puzyrev V.P. 2015. A comparison of genome-wide DNA methylation patterns between different vascular tissues from patients with coronary heart disease. PLoS One. 10 (4), e0122601.
Article PubMed PubMed Central Google Scholar
Krolevets M., Cate V.T., Prochaska J.H., Schulz A., Rapp S., Tenzer S., Andrade-Navarro M.A., Horvath S., Niehrs C., Wild P.S. 2023. DNA methylation and cardiovascular disease in humans: A systematic review and database of known CpG methylation sites. Clin. Epigenet. 15 (1), 56.
Shah A.A., Gregory S.G., Krupp D., Feng S., Dorogi A., Haynes C., Grass E., Lin S.S., Hauser E.R., Kraus W.E., Shah S.H., Hughes G.C. 2015. Epigenetic profiling identifies novel genes for ascending aortic aneurysm formation with bicuspid aortic valves. Heart Surg. Forum. 18 (4), E134–E139.
Pan S., Lai H., Shen Y., Breeze C., Beck S., Hong T., Wang C., Teschendorff A.E. 2017. DNA methylome analysis reveals distinct epigenetic patterns of ascending aortic dissection and bicuspid aortic valve. Cardiovasc. Res. 113 (6), 692–704.
Article CAS PubMed Google Scholar
Chen Y., Xu X., Chen Z., Huang B., Wang X., Fan X. 2022. DNA methylation alternation in Stanford-A acute aortic dissection. BMC Cardiovasc. Disord. 22 (1), 455.
Article CAS PubMed PubMed Central Google Scholar
Björck H.M., Du L., Pulignani S., Paloschi V., Lundströmer K., Kostina A.S., Österholm C., Malashicheva A., Kostareva A., Evangelista A., Teixidó-Tura G., Maleki S., Franco-Cereceda A., Eriksson P.; Mechanistic interrogation of bicuspid aortic valve associated aortopathy (MIBAVA) Leducq Consortium. 2018. altered DNA methylation indicates an oscillatory flow mediated epithelial-to-mesenchymal transition signature in ascending aorta of patients with bicuspid aortic valve. Sci. Rep. 8 (1), 2777.
Liu P., Zhang J., Du D., Zhang D., Jin Z., Qiu W., Zhou X., Dong S., Zhou M., Zhao H., Zhang W., Ma J., Sun S., Fu W., Liu Y., Wang L. 2021. Altered DNA methylation pattern reveals epigenetic regulation of Hox genes in thoracic aortic dissection and serves as a biomarker in disease diagnosis. Clin. Epigenet. 13 (1), 124.
Maredia A., Guzzardi D., Aleinati M., Iqbal F., Khaira A., Madhu A., Wang X., Barker A.J., McCarthy P.M., Fedak P.W.M., Greenway S.C. 2021. Aorta-specific DNA methylation patterns in cell-free DNA from patients with bicuspid aortic valve-associated aortopathy. Clin. Epigenet. 13 (1), 147.
Zhang H., Liu B., Shi X., Sun X. 2021. Long noncoding RNAs: potential therapeutic targets in cardiocerebrovascular diseases. Pharmacol. Ther. 221, 107744.
Article CAS PubMed Google Scholar
Sun J., Chen G., Jing Y., He X., Dong J., Zheng J., Zou M., Li H., Wang S., Sun Y., Liao W., Liao Y., Feng L., Bin J. 2018. LncRNA expression profile of human thoracic aortic dissection by high-throughput sequencing. Cell Physiol. Biochem. 46 (3), 1027–1041.
Article CAS PubMed Google Scholar
Lim Y.H., Ryu J., Kook H., Kim Y.K. 2020. Identification of long noncoding RNAs involved in differentiation and survival of vascular smooth muscle cells. Mol. Ther. Nucleic Acids. 22, 209–221.
Article CAS PubMed PubMed Central Google Scholar
Du L., Li X., Gao Q., Yuan P., Sun Y., Chen Y., Huang B., Deng Y., Wang B. 2022. LncRNA nuclear receptor subfamily 2 group F member 1 antisense RNA 1 (NR2F1-AS1) aggravates nucleus pulposus cell apoptosis and extracellular matrix degradation. Bioengineered. 13 (2), 2746–2762.
Article CAS PubMed PubMed Central Google Scholar
Fasolo F., Di Gregoli K., Maegdefessel L., Johnson J.L. 2019). Non-coding RNAs in cardiovascular cell biology and atherosclerosis. Cardiovascular Res. 115 (12), 1732–1756.
Nazarenko M.S., Markov A.V., Koroleva Yu.A., Sleptsov A.A., Kazantsev A.N., Barbarash O.L., Puzyrev V.P. 2017. Identification of differently metylated genes potentially related to human atherosclerosis. Ross. Kardiol. Zh. 10, 42‒48. https://doi.org/10.15829/1560-4071-2017-10-42-48
Cassandri M., Smirnov A., Novelli F., Pitolli C., Agostini M., Malewicz M., Melino G., Raschellà G. 2017. Zinc-finger proteins in health and disease. Cell Death Discovery 3, 17071.
Article PubMed PubMed Central Google Scholar
Dhaouadi N., Li J.Y., Feugier P., Gustin M.P., Dab H., Kacem K., Bricca G., Cerutti C. 2014. Computational identification of potential transcriptional regulators of TGF-β1 in human atherosclerotic arteries. Genomics. 103 (5–6), 357–370.
Article CAS PubMed Google Scholar
Albrecht C., Preusch M.R., Hofmann G., Morris-Rosenfeld S., Blessing E., Rosenfeld M.E., Katus H.A., Bea F. 2010. Egr-1 deficiency in bone marrow-derived cells reduces atherosclerotic lesion formation in a hyperlipidaemic mouse model. Cardiovasc. Res. 86 (2), 321–329.
Article CAS PubMed Google Scholar
Karunakaran D., Thrush A.B., Nguyen M.A., Richards L., Geoffrion M., Singaravelu R., Ramphos E., Shangari P., Ouimet M., Pezacki J.P., Moore K.J., Perisic L., Maegdefessel L., Hedin U., Harper M.E., Rayner K.J. 2015. Macrophage mitochondrial energy status regulates cholesterol efflux and is enhanced by anti-mir33 in atherosclerosis. Circ. Res. 117 (3), 266–278.
Article CAS PubMed PubMed Central Google Scholar
Nurnberg S.T., Cheng K., Raiesdana A., Kundu R., Miller C.L., Kim J.B., Arora K., Carcamo-Oribe I., Xiong Y., Tellakula N., Nanda V., Murthy N., Boisvert W.A., Hedin U., Perisic L., Aldi S., Maegdefessel L., Pjanic M., Owens G.K., Tallquist M.D., Quertermous T. 2015. Coronary artery disease associated transcription factor TCF21 regulates smooth muscle precursor cells that contribute to the fibrous cap. PLoS Genet. 11 (5), e1005155.
Article PubMed PubMed Central Google Scholar
Haldar S.M., Lu Y., Jeyaraj D., Kawanami D., Cui Y., Eapen S.J., Hao C., Li Y., Doughman Y.Q., Watana-be M., Shimizu K., Kuivaniemi H., Sadoshima J., Margulies K.B., Cappola T.P., Jain M.K. 2010. Klf15 deficiency is a molecular link between heart failure and aortic aneurysm formation. Sci. Transl. Med. 2 (26), 26ra26.
Comments (0)