Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E et al (2019) Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nat Genet 51(1):63–75

Article  CAS  PubMed  Google Scholar 

Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H et al (2019) Identification of common genetic risk variants for autism spectrum disorder. Nat Genet 51(3):431–444

Article  CAS  PubMed  PubMed Central  Google Scholar 

Genomic Dissection of Bipolar Disorder and Schizophrenia (2018) Including 28 Subphenotypes. Cell 173(7):1705-1715.e1716

Google Scholar 

Mullins N, Forstner AJ, O’Connell KS, Coombes B, Coleman JRI, Qiao Z et al (2021) Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nat Genet 53(6):817–829

Article  CAS  PubMed  PubMed Central  Google Scholar 

Howard DM, Adams MJ, Clarke TK, Hafferty JD, Gibson J, Shirali M et al (2019) Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. Nat Neurosci 22(3):343–352

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cui Y, Peng F, Wang D, Li Y, Li JS, Li L et al (2022) 3’aQTL-atlas: an atlas of 3’UTR alternative polyadenylation quantitative trait loci across human normal tissues. Nucleic Acids Res 50(D1):D39–D45

Article  CAS  PubMed  Google Scholar 

Battle DE (2013) Diagnostic and Statistical Manual of Mental Disorders (DSM). Codas 25(2):191–192

PubMed  Google Scholar 

Costello EJ, Egger H, Angold A (2005) 10-Year research update review: the epidemiology of child and adolescent psychiatric disorders: I. Methods and public health burden. J Am Acad Child Adolesc Psychiatry 44(10):972–986

Article  PubMed  Google Scholar 

Saha S, Chant D, Welham J, McGrath J (2005) A systematic review of the prevalence of schizophrenia. PLoS Med 2(5):e141

Article  PubMed  PubMed Central  Google Scholar 

Gonda X, Petschner P, Eszlari N, Baksa D, Edes A, Antal P et al (2019) Genetic variants in major depressive disorder: From pathophysiology to therapy. Pharmacol Ther 194:22–43

Article  CAS  PubMed  Google Scholar 

Kessler RC, Bromet EJ The epidemiology of depression across cultures. (1545–2093 (Electronic)).

Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA (2007) The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry 164(6):942–948

Article  PubMed  Google Scholar 

Holt R, Barnby G, Maestrini E, Bacchelli E, Brocklebank D, Sousa I et al (2010) Linkage and candidate gene studies of autism spectrum disorders in European populations. Eur J Human Genet EJHG 18(9):1013–1019

Article  CAS  PubMed  Google Scholar 

Baird G, Simonoff E, Pickles A, Chandler S, Loucas T, Meldrum D et al (2006) Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP). The Lancet 368(9531):210–215

Article  Google Scholar 

Müller JK, Leweke FM (2016) Bipolar disorder: clinical overview. Med Monatsschr Pharm 39(9):363–369

PubMed  Google Scholar 

Plomin R, Owen MJ, McGuffin P (1994) The genetic basis of complex human behaviors. Science 264(5166):1733–1739

Article  CAS  PubMed  ADS  Google Scholar 

Arango C, Dragioti E, Solmi M, Cortese S, Domschke K, Murray RM et al (2021) Risk and protective factors for mental disorders beyond genetics: an evidence-based atlas. World Psychiatry 20(3):417–436

Article  PubMed  PubMed Central  Google Scholar 

Eubig PA, Aguiar A, Schantz SL (2010) Lead and PCBs as risk factors for attention deficit/hyperactivity disorder. Environ Health Perspect 118(12):1654–1667

Article  CAS  PubMed  PubMed Central  Google Scholar 

Keil KP, Lein PJ. DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum disorders? Environ Epigenet 2016; 2(1).

Lichtenstein P, Yip BH, Björk C, Pawitan Y, Cannon TD, Sullivan PF et al (2009) Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. The Lancet 373(9659):234–239

Article  CAS  Google Scholar 

Grimm O, Kranz TM, Reif A (2020) Genetics of ADHD: what should the clinician know? Curr Psychiatry Rep 22(4):18–18

Article  PubMed  PubMed Central  Google Scholar 

Colvert E, Tick B, McEwen F, Stewart C, Curran SR, Woodhouse E et al (2015) Heritability of autism spectrum disorder in a UK population-based twin sample. JAMA Psychiat 72(5):415–423

Article  Google Scholar 

Cheng S, Guan F, Ma M, Zhang L, Cheng B, Qi X et al (2020) An atlas of genetic correlations between psychiatric disorders and human blood plasma proteome. Eur Psychiatry 63(1):e17

Article  PubMed  PubMed Central  Google Scholar 

Zheng Z-H, Tu J-L, Li X-H, Hua Q, Liu W-Z, Liu Y et al (2021) Neuroinflammation induces anxiety- and depressive-like behavior by modulating neuronal plasticity in the basolateral amygdala. Brain Behav Immun 91:505–518

Article  CAS  PubMed  Google Scholar 

Konarski JZ, McIntyre RS, Grupp LA, Kennedy SH (2005) Is the cerebellum relevant in the circuitry of neuropsychiatric disorders? J Psychiatry Neurosci JPN 30(3):178–186

PubMed  Google Scholar 

Ellison-Wright I, Bullmore E (2010) Anatomy of bipolar disorder and schizophrenia: a meta-analysis. Schizophr Res 117(1):1–12

Article  PubMed  Google Scholar 

Li L, Huang K-L, Gao Y, Cui Y, Wang G, Elrod ND et al (2021) An atlas of alternative polyadenylation quantitative trait loci contributing to complex trait and disease heritability. Nat Genet 53(7):994–1005

Article  CAS  PubMed  Google Scholar 

Sheng G, dos Reis M, Stern CD (2003) Churchill, a zinc finger transcriptional activator, regulates the transition between gastrulation and neurulation. Cell 115(5):603–613

Article  CAS  PubMed  Google Scholar 

Human genomics (2015) The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science 348(6235):648–660

Article  Google Scholar 

Li H, Durbin R (2009) Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25(14):1754–1760

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lindenbaum P, Redon R (2018) bioalcidae, samjs and vcffilterjs: object-oriented formatters and filters for bioinformatics files. Bioinformatics 34(7):1224–1225

Article  CAS  PubMed  Google Scholar 

Shabalin AA (2012) Matrix eQTL: ultra fast eQTL analysis via large matrix operations. Bioinformatics 28(10):1353–1358

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stegle O, Parts L, Piipari M, Winn J, Durbin R (2012) Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses. Nat Protoc 7(3):500–507

Article  CAS  PubMed  PubMed Central  Google Scholar 

Storey JD, Tibshirani R (2003) Statistical significance for genomewide studies. Proc Natl Acad Sci U S A 100(16):9440–9445

Article  MathSciNet  CAS  PubMed  PubMed Central  ADS  Google Scholar 

de Leeuw CA, Mooij JM, Heskes T, Posthuma D (2015) MAGMA: generalized gene-set analysis of GWAS data. PLoS Comput Biol 11(4):e1004219

Article  PubMed  PubMed Central  Google Scholar 

de Leeuw CA, Neale BM, Heskes T, Posthuma D (2016) The statistical properties of gene-set analysis. Nat Rev Genet 17(6):353–364

Article  PubMed  Google Scholar 

de Leeuw CA, Stringer S, Dekkers IA, Heskes T, Posthuma D (2018) Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure. Nat Commun 9(1):3768

Article  PubMed  PubMed Central  ADS  Google Scholar 

Subramanian A, Tamayo P Fau - Mootha VK, Mootha Vk Fau - Mukherjee S, Mukherjee S, Fau-Ebert BL, Ebert Bl Fau-Gillette MA, Gillette Ma Fau - Paulovich A, et al Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. (0027–8424 (Print)).

Davis AP, Grondin CJ, Johnson RJ, Sciaky D, Wiegers J, Wiegers TC et al (2021) Comparative Toxicogenomics Database (CTD): update 2021. Nucleic Acids Res 49(D1):D1138-d1143

Article  CAS  PubMed  Google Scholar 

Davis AP, Grondin CJ, Lennon-Hopkins K, Saraceni-Richards C, Sciaky D, King BL et al (2015) The Comparative Toxicogenomics Database’s 10th year anniversary: update 2015. Nucleic Acids Res 43(Database issue):D914-920

Article  CAS  PubMed  Google Scholar