Girardeau, G. & Lopes-Dos-Santos, V. Brain neural patterns and the memory function of sleep. Science 374, 560–564 (2021).
Article CAS PubMed PubMed Central Google Scholar
Frank, M. G. & Heller, H. C. The function(s) of sleep. Handb. Exp. Pharmacol. 253, 3–34 (2019). A very accessible and comprehensive review of current thinking and evidence concerning the functions of sleep.
Article CAS PubMed Google Scholar
Hertenstein, E., Benz, F., Schneider, C. & Baglioni, C. Insomnia—a risk factor for mental disorders. J. Sleep. Res. 22, e13930 (2023).
Wu, T. T. et al. Insomnia and multiple health outcomes: umbrella review of meta-analyses of prospective cohort studies. Public. Health 215, 66–74 (2023).
Article CAS PubMed Google Scholar
Koronowski, K. B. & Sassone-Corsi, P. Communicating clocks shape circadian homeostasis. Science 371, eabd0951 (2021). This review highlights the concept of ‘circadian homeostasis’ by putting the network of circadian circuitries present in various tissues into a homeostatic context.
Article CAS PubMed PubMed Central Google Scholar
Hastings, M. H., Maywood, E. S. & Brancaccio, M. The mammalian circadian timing system and the suprachiasmatic nucleus as its pacemaker. Biology 8, 13 (2019).
Article CAS PubMed PubMed Central Google Scholar
Tu, B. P. & McKnight, S. L. Metabolic cycles as an underlying basis of biological oscillations. Nat. Rev. Mol. Cell Biol. 7, 696–701 (2006).
Article CAS PubMed Google Scholar
Daan, S., Beersma, D. G. & Borbely, A. A. Timing of human sleep: recovery process gated by a circadian pacemaker. Am. J. Physiol. 246, R161–R183 (1984). This paper provides a quantitative exploration of how the interaction between sleep homeostasis and circadian rhythmicity explains a broad range of sleep phenomena.
Borbely, A. A. A two process model of sleep regulation. Hum. Neurobiol. 1, 195–204 (1982).
Edgar, D. M., Dement, W. C. & Fuller, C. A. Effect of SCN lesions on sleep in squirrel monkeys: evidence for opponent processes in sleep-wake regulation. J. Neurosci. 13, 1065–1079 (1993).
Article CAS PubMed PubMed Central Google Scholar
Shafer, O. T. & Keene, A. C. The regulation of Drosophila sleep. Curr. Biol. 31, R38–R49 (2021).
Article CAS PubMed Google Scholar
Chiu, C. N. & Prober, D. A. Regulation of zebrafish sleep and arousal states: current and prospective approaches. Front. Neural Circuits 7, 58 (2013).
Article PubMed PubMed Central Google Scholar
Krueger, J. M., Nguyen, J. T., Dykstra-Aiello, C. J. & Taishi, P. Local sleep. Sleep. Med. Rev. 43, 14–21 (2019).
Noya, S. B. et al. The forebrain synaptic transcriptome is organized by clocks but its proteome is driven by sleep. Science 366, eaav2642 (2019).
Article CAS PubMed Google Scholar
Delorme, J. et al. Hippocampal neurons’ cytosolic and membrane-bound ribosomal transcript profiles are differentially regulated by learning and subsequent sleep. Proc. Natl Acad. Sci. USA 118, e2108534118 (2021).
Article CAS PubMed PubMed Central Google Scholar
Bellesi, M., de Vivo, L., Tononi, G. & Cirelli, C. Effects of sleep and wake on astrocytes: clues from molecular and ultrastructural studies. BMC Biol. 13, 66 (2015).
Article PubMed PubMed Central Google Scholar
Zepelin, H. S. & Tobler, I. in Principles and Practise of Sleep Medicine, 4th edition (ed. Roth Kryger, D.) Ch. 8, 91–100 (Elsevier Saunders, 2005).
Barbato, G., Barker, C., Bender, C. & Wehr, T. A. Spontaneous sleep interruptions during extended nights. Relationships with NREM and REM sleep phases and effects on REM sleep regulation. Clin. Neurophysiol. 113, 892–900 (2002).
Simor, P., van der Wijk, G., Nobili, L. & Peigneux, P. The microstructure of REM sleep: why phasic and tonic. Sleep. Med. Rev. 52, 101305 (2020).
Stephan, A. M., Lecci, S., Cataldi, J. & Siclari, F. Conscious experiences and high-density EEG patterns predicting subjective sleep depth. Curr. Biol. 31, 5487–5500.e3 (2021).
Article CAS PubMed Google Scholar
Osorio-Forero, A. et al. Noradrenergic circuit control of non-REM sleep substates. Curr. Biol. 31, 5009–5023.e7 (2021).
Article CAS PubMed Google Scholar
Lecci, S. et al. Electroencephalographic changes associated with subjective under- and overestimation of sleep duration. Sleep 43, zsaa094 (2020).
Cajochen, C., Wyatt, J. K., Czeisler, C. A. & Dijk, D. J. Separation of circadian and wake duration-dependent modulation of EEG activation during wakefulness. Neuroscience 114, 1047–1060 (2002).
Article CAS PubMed Google Scholar
Davis, C. J., Clinton, J. M., Jewett, K. A., Zielinski, M. R. & Krueger, J. M. Delta wave power: an independent sleep phenotype or epiphenomenon? J. Clin. Sleep. Med. 7, S16–S18 (2011).
Article PubMed PubMed Central Google Scholar
Wang, D. et al. Slow wave sleep in patients with respiratory failure. Sleep. Med. 12, 378–383 (2011).
Aeschbach, D., Dijk, D. J., Trachsel, L., Brunner, D. P. & Borbely, A. A. Dynamics of slow-wave activity and spindle frequency activity in the human sleep EEG: effect of midazolam and zopiclone. Neuropsychopharmacology 11, 237–244 (1994).
Article CAS PubMed Google Scholar
Franken, P., Dijk, D. J., Tobler, I. & Borbely, A. A. Sleep deprivation in rats: effects on EEG power spectra, vigilance states, and cortical temperature. Am. J. Physiol. 261, R198–R208 (1991).
Achermann, P., Dijk, D. J., Brunner, D. P. & Borbely, A. A. A model of human sleep homeostasis based on EEG slow-wave activity: quantitative comparison of data and simulations. Brain Res. Bull. 31, 97–113 (1993).
Article CAS PubMed Google Scholar
Thomas, C. W., Guillaumin, M. C., McKillop, L. E., Achermann, P. & Vyazovskiy, V. V. Global sleep homeostasis reflects temporally and spatially integrated local cortical neuronal activity. eLife 9, e54148 (2020).
Article PubMed PubMed Central Google Scholar
Franken, P., Tobler, I. & Borbely, A. A. Sleep homeostasis in the rat: simulation of the time course of EEG slow-wave activity. Neurosci. Lett. 130, 141–144 (1991). This paper provides a quantitative account of how the distribution of sleep and wakefulness drives the time course of slow wave activity in the rat.
Article CAS PubMed Google Scholar
Franken, P., Chollet, D. & Tafti, M. The homeostatic regulation of sleep need is under genetic control. J. Neurosci. 21, 2610–2621 (2001).
Article CAS PubMed PubMed Central Google Scholar
Rusterholz, T., Durr, R. & Achermann, P. Inter-individual differences in the dynamics of sleep homeostasis. Sleep 33, 491–498 (2010).
Article PubMed PubMed Central Google Scholar
Huber, R., Tononi, G. & Cirelli, C. Exploratory behavior, cortical BDNF expression, and sleep homeostasis. Sleep 30, 129–139 (2007).
Vassalli, A. & Franken, P. Hypocretin (orexin) is critical in sustaining theta/gamma-rich waking behaviors that drive sleep need. Proc. Natl Acad. Sci. USA 114, E5464–E5473 (2017).
Article CAS PubMed PubMed Central Google Scholar
Dijk, D. J., Brunner, D. P. & Borbely, A. A. Time course of EEG power density during long sleep in humans. Am. J. Physiol. 258, R650–R661 (1990).
Hubbard, J. et al. Rapid fast-delta decay following prolonged wakefulness marks a phase of wake-inertia in NREM sleep. Nat. Commun. 11, 3130 (2020).
Article CAS PubMed PubMed Central Google Scholar
Rosenthal, L., Merlotti, L., Roehrs, T. A. & Roth, T. Enforced 24-hour recovery following sleep deprivation. Sleep 14, 448–453 (1991).
Article CAS PubMed Google Scholar
Franken, P., Malafosse, A. & Tafti, M. Genetic determinants of sleep regulation in inbred mice. Sleep 22, 155–169 (1999).
Diessler, S. et al. A systems genetics resource and analysis of sleep regulation in the mouse. PLoS Biol. 16, e2005750 (2018).
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