Wilt, B. A. et al. Advances in light microscopy for neuroscience. Annu. Rev. Neurosci. 32, 435–506 (2009).
Article CAS PubMed PubMed Central Google Scholar
Svoboda, K., Denk, W., Kleinfeld, D. & Tank, D. W. In vivo dendritic calcium dynamics in neocortical pyramidal neurons. Nature 385, 161–165 (1997).
Article CAS PubMed Google Scholar
Waters, J., Larkum, M., Sakmann, B. & Helmchen, F. Supralinear Ca2+ influx into dendritic tufts of layer 2/3 neocortical pyramidal neurons in vitro and in vivo. J. Neurosci. 23, 8558–8567 (2003).
Article CAS PubMed PubMed Central Google Scholar
Chen, X., Leischner, U., Rochefort, N. L., Nelken, I. & Konnerth, A. Functional mapping of single spines in cortical neurons in vivo. Nature 475, 501–505 (2011).
Article CAS PubMed Google Scholar
Trachtenberg, J. T. et al. Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex. Nature 420, 788–794 (2002).
Article CAS PubMed Google Scholar
Grutzendler, J., Kasthuri, N. & Gan, W. B. Long-term dendritic spine stability in the adult cortex. Nature 420, 812–816 (2002).
Article CAS PubMed Google Scholar
Zuo, Y., Yang, G., Kwon, E. & Gan, W.-B. Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex. Nature 436, 261–265 (2005).
Article CAS PubMed Google Scholar
Holtmaat, A., Wilbrecht, L., Knott, G. W., Welker, E. & Svoboda, K. Experience-dependent and cell-type-specific spine growth in the neocortex. Nature 441, 979–983 (2006).
Article CAS PubMed Google Scholar
Lendvai, B., Stern, E. A., Chen, B. & Svoboda, K. Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo. Nature 404, 876–881 (2000).
Article CAS PubMed Google Scholar
Tian, L. et al. Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nat. Methods 6, 875–881 (2009).
Article CAS PubMed PubMed Central Google Scholar
Chen, J. L. et al. Pathway-specific reorganization of projection neurons in somatosensory cortex during learning. Nat. Neurosci. 18, 1101–1108 (2015).
Condylis, C. et al. Dense functional and molecular readout of a circuit hub in sensory cortex. Science 375, eabl5981 (2022).
Article CAS PubMed PubMed Central Google Scholar
O’Toole, S. M., Oyibo, H. K. & Keller, G. B. Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses. Neuron 111, 2918–2928.e8 (2023).
Zuend, M. et al. Arousal-induced cortical activity triggers lactate release from astrocytes. Nat. Metab. 2, 179–191 (2020).
Article CAS PubMed Google Scholar
Helmchen, F. & Denk, W. Deep tissue two-photon microscopy. Nat. Methods 2, 932–940 (2005).
Article CAS PubMed Google Scholar
Denk, W., Strickler, J. H. & Webb, W. W. Two-photon laser scanning fluorescence microscopy. Science 248, 73–76 (1990).
Article CAS PubMed Google Scholar
Kerr, J. N. D. & Denk, W. Imaging in vivo: watching the brain in action. Nat. Rev. Neurosci. 9, 195–205 (2008).
Article CAS PubMed Google Scholar
Svoboda, K. & Yasuda, R. Principles of two-photon excitation microscopy and its applications to neuroscience. Neuron 50, 823–839 (2006).
Article CAS PubMed Google Scholar
Pologruto, T. A., Yasuda, R. & Svoboda, K. Monitoring neural activity and [Ca2+] with genetically encoded Ca2+ indicators. J. Neurosci. 24, 9572–9579 (2004).
Article CAS PubMed PubMed Central Google Scholar
Abdelfattah, A. S. et al. Bright and photostable chemigenetic indicators for extended in vivo voltage imaging. Science 365, 699–704 (2019).
Article CAS PubMed Google Scholar
Zhang, Y. et al. Fast and sensitive GCaMP calcium indicators for imaging neural populations. Nature 615, 884–891 (2023).
Article CAS PubMed PubMed Central Google Scholar
Lee, S. et al. Improving positively tuned voltage indicators for brightness and kinetics. Preprint at bioRxiv https://doi.org/10.1101/2024.06.21.599617 (2024).
Dombeck, D. A., Harvey, C. D., Tian, L., Looger, L. L. & Tank, D. W. Functional imaging of hippocampal place cells at cellular resolution during virtual navigation. Nat. Neurosci. 13, 1433–1440 (2010).
Article CAS PubMed PubMed Central Google Scholar
Barretto, R. P. J., Messerschmidt, B. & Schnitzer, M. J. In vivo fluorescence imaging with high-resolution microlenses. Nat. Methods 6, 511–512 (2009).
Article CAS PubMed PubMed Central Google Scholar
Horton, N. G. et al. In vivo three-photon microscopy of subcortical structures within an intact mouse brain. Nat. Photon. 7, 205–209 (2013). This paper three-photon microscopy for in vivo imaging of subcortical structures in an intact mouse brain, establishing the potential of the technique for deep tissue imaging.
Wang, T. & Xu, C. Three-photon neuronal imaging in deep mouse brain. Optica 7, 947 (2020).
Squier, J. A., Müller, M., Brakenhoff, G. J. & Wilson, K. R. Third harmonic generation microscopy. Opt. Express 3, 315 (1998).
Article CAS PubMed Google Scholar
Weigelin, B., Bakker, G.-J. & Friedl, P. Third harmonic generation microscopy of cells and tissue organization. J. Cell Sci. 129, 245–255 (2016).
Theer, P., Hasan, M. T. & Denk, W. Two-photon imaging to a depth of 1000 µm in living brains by use of a Ti:Al2O3 regenerative amplifier. Opt. Lett. 28, 1022–1024 (2003).
Article CAS PubMed Google Scholar
Akbari, N., Rebec, M. R., Xia, F. & Xu, C. Imaging deeper than the transport mean free path with multiphoton microscopy. Biomed. Opt. Express 13, 452 (2022).
Bakker, G. J. et al. Intravital deep-tumor single-beam 3-photon, 4-photon, and harmonic microscopy. eLife 11, e63776 (2022).
Article CAS PubMed PubMed Central Google Scholar
Wang, M. et al. Comparing the effective attenuation lengths for long wavelength in vivo imaging of the mouse brain. Biomed. Opt. Express 9, 3534 (2018).
Article CAS PubMed PubMed Central Google Scholar
Wang, M., Kim, M., Xia, F. & Xu, C. Impact of the emission wavelengths on in vivo multiphoton imaging of mouse brains. Biomed. Opt. Express 10, 1905 (2019).
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