Schuster I. Cytochromes P450 are essential players in the vitamin D signaling system. Biochim Biophys Acta. 2011;1814:186–99.
Bikle DD, Gee E, Halloran B, Kowalski MA, Ryzen E, Haddad JG. Assessment of the free fraction of 25-hydroxyvitamin D in serum and its regulation by albumin and the vitamin D-binding protein. J Clin Endocrinol Metab. 1986;63:954–9.
Chun RF, Peercy BE, Orwoll ES, Nielson CM, Adams JS, Hewison M. Vitamin D and DBP: the free hormone hypothesis revisited. J Steroid Biochem Mol Biol. 2014;144:132–7.
Nykjaer A, Dragun D, Walther D, Vorum H, Jacobsen C, Herz J, et al. An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3. Cell. 1999;96:507–15.
Bennour I, Haroun N, Sicard F, Mounien L, Landrier JF. Recent insights into vitamin D, adipocyte, and adipose tissue biology. Obes Rev. 2022;23:e13453
Landrier JF, Karkeni E, Marcotorchino J, Bonnet L, Tourniaire F. Vitamin D modulates adipose tissue biology: possible consequences for obesity?. Proc Nutr Soc. 2016;75:38–46.
Landrier JF, Marcotorchino J, Tourniaire F. Lipophilic micronutrients and adipose tissue biology. Nutrients. 2012;4:1622–49.
Article PubMed PubMed Central Google Scholar
Carlberg C. Nutrigenomics of vitamin D. Nutrients. 2019;11:676.
Article PubMed PubMed Central Google Scholar
Marcotorchino J, Gouranton E, Romier B, Tourniaire F, Astier J, Malezet C, et al. Vitamin D reduces the inflammatory response and restores glucose uptake in adipocytes. Mol Nutr Food Res. 2012;56:1771–82.
Marcotorchino J, Tourniaire F, Astier J, Karkeni E, Canault M, Amiot MJ, et al. Vitamin D protects against diet-induced obesity by enhancing fatty acid oxidation. J Nutr Biochem. 2014;25:1077–83.
Karkeni E, Marcotorchino J, Tourniaire F, Astier J, Peiretti F, Darmon P, et al. Vitamin D limits chemokine expression in adipocytes and macrophage migration in vitro and in male mice. Endocrinology. 2015;156:1782–93.
Karkeni E, Bonnet L, Marcotorchino J, Tourniaire F, Astier J, Ye J, et al. Vitamin D limits inflammation-linked microRNA expression in adipocytes in vitro and in vivo: A new mechanism for the regulation of inflammation by vitamin D. Epigenetics. 2018;13:156–62.
Article PubMed PubMed Central Google Scholar
Marziou A, Philouze C, Couturier C, Astier J, Obert P, Landrier JF, et al. Vitamin D supplementation improves adipose tissue inflammation and reduces hepatic steatosis in obese C57BL/6J mice. Nutrients. 2020;12:342.
Article PubMed PubMed Central Google Scholar
Park CY, Han SN. The role of vitamin D in adipose tissue biology: adipocyte differentiation, energy metabolism, and inflammation. J Lipid Atheroscler. 2021;10:130–44.
Article PubMed PubMed Central Google Scholar
Marziou A, Aubert B, Couturier C, Astier J, Philouze C, Obert P, et al. Combined Beneficial Effect of Voluntary Physical Exercise and Vitamin D Supplementation in Diet-induced Obese C57BL/6J Mice. Med Sci Sports Exercise. 2021;53:1883–94.
Karkeni E, Payet T, Astier J, Sicard F, Mounien L, Landrier JF. Proposal of a bioinformatics approach to predict molecular mechanisms involved in inflammatory response: case of ATRA and 1,25(OH)(2)D in adipocytes. Epigenetics. 2023;18:2201516.
Article PubMed PubMed Central Google Scholar
Payet T, Valmori M, Astier J, Svilar L, Sicard F, Tardivel C, et al. Vitamin D modulates lipid composition of adipocyte-derived extracellular vesicles under inflammatory conditions. Mol Nutr Food Res. 2023;67:e2300374
Bennour I, Haroun N, Sicard F, Mounien L, Landrier JF. Vitamin D and obesity/adiposity-A brief overview of recent studies. Nutrients. 2022;14:2049.
Article PubMed PubMed Central Google Scholar
Seipelt EM, Tourniaire F, Couturier C, Astier J, Loriod B, Vachon H, et al. Prenatal maternal vitamin D deficiency sex-dependently programs adipose tissue metabolism and energy homeostasis in offspring. FASEB J. 2020;34:14905–19.
Haroun N, Bennour I, Seipelt E, Astier J, Couturier C, Mounien L, et al. Maternal vitamin D deficiency in mice increases white adipose tissue inflammation in offspring. Cells. 2022;11:2024.
Article PubMed PubMed Central Google Scholar
Harahap IA, Landrier JF, Suliburska J. Interrelationship between vitamin D and calcium in obesity and its comorbid conditions. Nutrients. 2022;14:3187.
Article PubMed PubMed Central Google Scholar
Haroun N, Bennour I, Seipelt E, Astier J, Sani L, Tardivel C, et al. Maternal vitamin D deficiency in mice sex-dependently affects hepatic lipid accumulation in offspring. Mol Nutr Food Res. 2024;68:e2300290.
Saidi L, Hammou H, Sicard F, Landrier JF, Mounien L. Maternal vitamin D deficiency and brain functions: a never-ending story. Food Funct. 2023;14:6290–301.
Wamberg L, Christiansen T, Paulsen SK, Fisker S, Rask P, Rejnmark L, et al. Expression of vitamin D-metabolizing enzymes in human adipose tissue-the effect of obesity and diet-induced weight loss. Int J Obes (Lond). 2013;37:651–7.
Park JM, Park CY, Han SN. High fat diet-Induced obesity alters vitamin D metabolizing enzyme expression in mice. Biofactors. 2015;41:175–82.
Bonnet L, Hachemi MA, Karkeni E, Couturier C, Astier J, Defoort C, et al. Diet induced obesity modifies vitamin D metabolism and adipose tissue storage in mice. J Steroid Biochem Mol Biol. 2019;185:39–46.
Bonnet L, Karkeni E, Couturier C, Astier J, Defoort C, Svilar L, et al. Four days high fat diet modulates vitamin D metabolite levels and enzymes in mice. J Endocrinol. 2021;248:87–93.
Bournot L, Payet T, Marcotorchino J, Awada M, Rouquet T, Breniere T, et al. Vitamin D metabolism is altered during aging alone or combined with obesity in male mice. Biofactors. 2024;50:957–66.
Bournot L, Payet T, Sicard F, Breniere T, Astier J, Roux J, et al. Aging alone or combined with obesity increases white adipose tissue inflammatory status in male mice. Sci Rep. 2024;14:16268.
Article PubMed PubMed Central Google Scholar
Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, et al. Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med. 2013;10:e1001383.
Article PubMed PubMed Central Google Scholar
Mallard SR, Howe AS, Houghton LA. Vitamin D status and weight loss: a systematic review and meta-analysis of randomized and nonrandomized controlled weight-loss trials. Am J Clin Nutr. 2016;104:1151–9.
Pannu PK, Zhao Y, Soares MJ. Reductions in body weight and percent fat mass increase the vitamin D status of obese subjects: a systematic review and metaregression analysis. Nutr Res. 2016;36:201–13.
Landrier JF, Malezet-Desmoulins C, Reboul E, Marie Lorec A, Josephe Amiot M, Borel P. Comparison of different vehicles to study the effect of tocopherols on gene expression in intestinal cells. Free Radic Res. 2008;42:523–30.
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25:402–8.
Comments (0)