Kamar N, Dalton HR, Abravanel F, Izopet J (2014) Hepatitis E Virus Infection. Clin Microbiol Rev 27(1):116–138. https://doi.org/10.1128/CMR.00057-13

Article  CAS  PubMed  PubMed Central  Google Scholar 

Purdy MA et al (2022) ICTV Virus Taxonomy Profile: Hepeviridae 2022. J Gen Virol 103(9):001778. https://doi.org/10.1099/jgv.0.001778

Article  CAS  Google Scholar 

Rein DB, Stevens GA, Theaker J, Wittenborn JS, and Wiersma ST (2012) ‘The global burden of hepatitis E virus genotypes 1 and 2 in 2005’. Hepatol. Baltim Md 55(4) https://doi.org/10.1002/hep.25505.

WHO, ‘Hepatitis E’. Accessed: 07, 2025. [Online]. Available: https://www.who.int/news-room/fact-sheets/detail/hepatitis-e

Li P et al (2020) ‘The global epidemiology of hepatitis E virus infection: A systematic review and meta-analysis’, Liver Int. Off J Int Assoc Study Liver 40(7):1516–1528. https://doi.org/10.1111/liv.14468

Article  Google Scholar 

Primadharsini PP, Nagashima S, Okamoto H (2019) Genetic Variability and Evolution of Hepatitis E Virus. Viruses 11(5):456. https://doi.org/10.3390/v11050456

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yin X, Ambardekar C, Lu Y, Feng Z (2016) Distinct Entry Mechanisms for Nonenveloped and Quasi-Enveloped Hepatitis E Viruses. J Virol 90(8):4232–4242. https://doi.org/10.1128/jvi.02804-15

Article  CAS  PubMed  PubMed Central  Google Scholar 

Grange ZL et al (2021) Ranking the risk of animal-to-human spillover for newly discovered viruses. Proc Natl Acad Sci U S A 118(15):e2002324118. https://doi.org/10.1073/pnas.2002324118

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu T et al (2011) RNA interference induces effective inhibition of mRNA accumulation and protein expression of SHEV ORF3 gene in vitro. Curr Microbiol 62(5):1355–1362. https://doi.org/10.1007/s00284-010-9863-3

Article  CAS  PubMed  Google Scholar 

Kamar N et al (2008) Hepatitis E Virus and Chronic Hepatitis in Organ-Transplant Recipients. N Engl J Med 358(8):811–817. https://doi.org/10.1056/NEJMoa0706992

Article  CAS  PubMed  Google Scholar 

Krain LJ, Nelson KE, Labrique AB (2014) Host immune status and response to hepatitis E virus infection. Clin Microbiol Rev 27(1):139–165. https://doi.org/10.1128/CMR.00062-13

Article  CAS  PubMed  PubMed Central  Google Scholar 

Labrique AB et al (2012) Hepatitis E, a vaccine-preventable cause of maternal deaths. Emerg Infect Dis 18(9):1401–1404. https://doi.org/10.3201/eid1809.120241

Article  PubMed  PubMed Central  Google Scholar 

Pérez-Gracia MT, Suay-García B, Mateos-Lindemann ML (2017) Hepatitis E and pregnancy: current state. Rev Med Virol 27(3):e1929. https://doi.org/10.1002/rmv.1929

Article  PubMed  Google Scholar 

Khuroo MS, Khuroo MS (2016) Hepatitis E: an emerging global disease - from discovery towards control and cure. J Viral Hepat 23(2):68–79. https://doi.org/10.1111/jvh.12445

Article  CAS  PubMed  Google Scholar 

Friedman RC, Farh KK-H, Burge CB, Bartel DP (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19(1):92–105. https://doi.org/10.1101/gr.082701.108

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shrivastava S, Steele R, Ray R, Ray RB (2015) MicroRNAs: Role in Hepatitis C Virus pathogenesis. Genes Dis 2(1):35–45. https://doi.org/10.1016/j.gendis.2015.01.001

Article  PubMed  PubMed Central  Google Scholar 

Calin GA, Croce CM (2006) MicroRNA signatures in human cancers. Nat Rev Cancer 6(11):857–866. https://doi.org/10.1038/nrc1997

Article  CAS  PubMed  Google Scholar 

Ciccacci C et al (2013) MicroRNA genetic variations: association with type 2 diabetes. Acta Diabetol 50(6):867–872. https://doi.org/10.1007/s00592-013-0469-7

Article  CAS  PubMed  Google Scholar 

Newman MA, Hammond SM (2010) Emerging paradigms of regulated microRNA processing. Genes Dev 24(11):1086–1092. https://doi.org/10.1101/gad.1919710

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhao Y et al (2007) Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking miRNA-1-2. Cell 129(2):303–317. https://doi.org/10.1016/j.cell.2007.03.030

Article  CAS  PubMed  Google Scholar 

Fan B et al (2015) Heterogeneous Ribonucleoprotein K (hnRNP K) Binds miR-122, a Mature Liver-Specific MicroRNA Required for Hepatitis C Virus Replication. Mol Cell Proteomics MCP 14(11):2878–2886. https://doi.org/10.1074/mcp.M115.050344

Article  CAS  PubMed  Google Scholar 

Patil R, Salunke P, Karpe YA (2023) Unravelling the Tripartite Interactions Among Hepatitis E Virus RNA, miR-140 and hnRNP K. J Mol Biol 435(10):168050. https://doi.org/10.1016/j.jmb.2023.168050

Article  CAS  PubMed  Google Scholar 

Patil RN, Karpe YA (2020) Uncovering the Roles of miR-214 in Hepatitis E Virus Replication. J Mol Biol 432(19):5322–5342. https://doi.org/10.1016/j.jmb.2020.07.015

Article  CAS  PubMed  Google Scholar 

Hu J, Xu Y, Hao J, Wang S, Li C, Meng S (2012) MiR-122 in hepatic function and liver diseases. Protein Cell 3(5):364–371. https://doi.org/10.1007/s13238-012-2036-3

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kunden RD, Ghezelbash S, Khan JQ, Wilson JA (2020) Location specific annealing of miR-122 and other small RNAs defines an Hepatitis C Virus 5′ UTR regulatory element with distinct impacts on virus translation and genome stability. Nucleic Acids Res 48(16):9235–9249. https://doi.org/10.1093/nar/gkaa664

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang X et al (2017) Hepatitis B Virus-Encoded MicroRNA Controls Viral Replication. J Virol 91(10):e01919-e2016. https://doi.org/10.1128/JVI.01919-16

Article  PubMed  PubMed Central  Google Scholar 

Shi J, Sun J, Wu M, Hu N, Hu Y (2016) Hepatitis A virus-encoded miRNAs attenuate the accumulation of viral genomic RNAs in infected cells. Virus Genes 52(3):317–324. https://doi.org/10.1007/s11262-016-1306-1

Article  CAS  PubMed  Google Scholar 

Qian Z et al (2022) Hepatitis E virus-encoded microRNA promotes viral replication by inhibiting type I interferon. FASEB J 36(1):e22104. https://doi.org/10.1096/fj.202101042R

Article  CAS  PubMed  Google Scholar 

Baruah V, Bose S (2019) Computational identification of hepatitis E virus-encoded microRNAs and their targets in human. J Med Virol 91(8):1545–1552. https://doi.org/10.1002/jmv.25471

Article  CAS  PubMed  Google Scholar 

Haldipur B, Bhukya PL, Arankalle V, Lole K (2018) Positive Regulation of Hepatitis E Virus Replication by MicroRNA-122. J Virol 92(11):e01999-e2017. https://doi.org/10.1128/JVI.01999-17

Article  CAS  PubMed