Lugner M, Rawshani A, Helleryd E, Eliasson B. Identifying top ten predictors of type 2 diabetes through machine learning analysis of UK biobank data. Sci Rep. 2024;14(1):2102.
CAS PubMed PubMed Central Google Scholar
Zhou B, Lu Y, Hajifathalian K, Bentham J, Di Cesare M, Danaei G, et al. Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4· 4 million participants. Lancet. 2016;387(10027):1513–30.
Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the international diabetes federation diabetes atlas. Diabetes Res Clin Pract. 2019;157:107843.
Ong KL, Stafford LK, McLaughlin SA, Boyko EJ, Vollset SE, Smith AE, et al. Global, regional, and National burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the global burden of disease study 2021. Lancet. 2023;402(10397):203–34.
Karimi M, Vakili K, Rashidian P, Razavi-Amoli SK, Akhbari M, Kazemi K. Effect of boswellia (Boswellia Serrata L.) supplementation on glycemic markers and lipid profile in type 2 diabetic patients: a systematic review and meta-analysis. Front Clin Diabetes Healthc. 2024;5:1466408.
PubMed PubMed Central Google Scholar
Karim M, Pirzad S, Shirsalimi N, Hosseini MH, Ebrahimi P, Khoshdooz S, et al. Effects of saffron (Crocus sativus L.) supplementation on cardiometabolic indices in diabetic and prediabetic overweight patients: a systematic review and meta-analysis of RCTs. Diabetol Metab Syndr. 2024;16(1):286.
CAS PubMed PubMed Central Google Scholar
Karimi M, Pirzad S, Pourfaraji SMA, Sedgi FM, Darouei B, Amani-Beni R, et al. Effects of black seed (Nigella sativa L.) on cardiometabolic indices in type 2 diabetic patients: A systematic review and meta-analysis of RCTs. Complement Ther Med. 2025;90:103174.
Karimi M, Pirzad S, Shirsalimi N, Ahmadizad S, Hashemi SM, Karami S, et al. Effects of Chia seed (Salvia Hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs. Nutr Metab (Lond). 2024;21(1):74.
Wagh VD. Propolis: a Wonder bees product and its Pharmacological potentials. Adv Pharmacol Pharm Sci. 2013;2013(1):308249.
Kılıç ZGK, Erdem S, Kabakcı D, Akdeniz G. Recent studies in the use of propolis as a traditional medicine: A review. Bee Stud. 2020;12(1):13–7.
Salatino A, Salatino MLF. Scientific note: often quoted, but not factual data about propolis composition. Apidologie. 2021;52:312–4.
Ghisalberti E. Propolis: a review. Bee World. 1979;60(2):59–84.
Park YK, Alencar SM, Aguiar CL. Botanical origin and chemical composition of Brazilian propolis. J Agric Food Chem. 2002;50(9):2502–6.
Sahinler N, Kaftanoglu O. Natural product propolis: chemical composition. Nat Prod Res. 2005;19(2):183–8.
Gheflati A, Dehnavi Z, Yazdi AG, Khorasanchi Z, Raeisi-Dehkordi H, Ranjbar G. The effects of propolis supplementation on metabolic parameters: A systematic review and meta-analysis of randomized controlled clinical trials. Avicenna J Phytomedicine. 2021;11(6):551.
Adeli S, Maroofi M, Tabrizi FPF, Alipour B, Heidari M, Vajdi M et al. Effects of Propolis consumption on glycemic indices and liver enzymes in adults: A grading of recommendations assessment, development, and valuation-assessed systematic review and Dose-Response Meta-analysis. Clin Ther. 2024.
Balica G, Vostinaru O, Stefanescu C, Mogosan C, Iaru I, Cristina A, et al. Potential role of propolis in the prevention and treatment of metabolic diseases. Plants. 2021;10(5):883.
CAS PubMed PubMed Central Google Scholar
Zakerkish M, Jenabi M, Zaeemzadeh N, Hemmati AA, Neisi N. The effect of Iranian propolis on glucose metabolism, lipid profile, insulin resistance, renal function and inflammatory biomarkers in patients with type 2 diabetes mellitus: A randomized double-blind clinical trial. Sci Rep. 2019;9(1):7289.
PubMed PubMed Central Google Scholar
Sarkis-Onofre R, Catalá-López F, Aromataris E, Lockwood C. How to properly use the PRISMA statement. Syst Reviews. 2021;10:1–3.
Amir-Behghadami M, Janati A, Population. Intervention, comparison, outcomes and study (PICOS) design as a framework to formulate eligibility criteria in systematic reviews. Emerg Med J. 2020.
Flemyng E, Moore TH, Boutron I, Higgins JP, Hróbjartsson A, Nejstgaard CH, et al. Using risk of Bias 2 to assess results from randomised controlled trials: guidance from Cochrane. BMJ Evidence-Based Med. 2023;28(4):260–6.
Prasad M. Introduction to the GRADE tool for rating certainty in evidence and recommendations. Clin Epidemiol Global Health. 2024;25:101484.
DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177–88.
Borenstein M, Hedges LV, Higgins JP, Rothstein HR. Introduction to meta-analysis: Wiley; 2011.
Hozo SP, Djulbegovic B, Hozo I. Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol. 2005;5(1):1–10.
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ (Clinical Res ed). 2003;327(7414):557–60.
Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539–58.
Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ (Clinical Res ed). 1997;315(7109):629–34.
Fukuda T, Fukui M, Tanaka M, Senmaru T, Iwase H, Yamazaki M, et al. Effect of Brazilian green propolis in patients with type 2 diabetes: A double-blind randomized placebo-controlled study. Biomedical Rep. 2015;3(3):355–60.
El-Sharkawy HM, Anees MM, Van Dyke TE. Propolis improves periodontal status and glycemic control in patients with type 2 diabetes mellitus and chronic periodontitis: a randomized clinical trial. J Periodontol. 2016;87(12):1418–26.
Zhao L, Pu L, Wei J, Li J, Wu J, Xin Z, et al. Brazilian green propolis improves antioxidant function in patients with type 2 diabetes mellitus. Int J Environ Res Public Health. 2016;13(5):498.
PubMed PubMed Central Google Scholar
Gao W, Pu L, Wei J, Yao Z, Wang Y, Shi T, et al. Serum antioxidant parameters are significantly increased in patients with type 2 diabetes mellitus after consumption of Chinese propolis: A randomized controlled trial based on fasting serum glucose level. Diabetes Therapy. 2018;9:101–11.
Afsharpour F, Javadi M, Hashemipour S, Koushan Y. Propolis supplementation improves glycemic and antioxidant status in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled study. Complement Ther Med. 2019;43:283–8.
Afsharpour F, Javadi M, Hashemipour S, Koushan Y, Haghighian HK. Changes in lipid profile, liver enzymes and inflammatory factors following oral supplementation with Propolis in patients with type 2 diabetes. Clin Diabetol. 2022;11(4):224–31.
Hesami S, Hashemipour S, Shiri-Shahsavar MR, Koushan Y, Haghighian HK. Administration of Iranian Propolis attenuates oxidative stress and blood glucose in type II diabetic patients: A randomized, double-blind, placebo-controlled, clinical trial. Caspian J Intern Med. 2019;10(1):48.
PubMed PubMed Central Google Scholar
Yousefi M, Hashemipour S, Shiri-Shahsavar MR, Koushan Y, Haghighian HK. Reducing the inflammatory interleukins with Anti-Inflammatory and antioxidant effects of Propolis in patients with type 2 diabetes: Double-Blind, randomized controlled, clinical trial. Clin Diabetol. 2023;12(6).
Ochoa-Morales PD, González-Ortiz M, Martínez-Abundis E, Pérez-Rubio KG, Patiño-Laguna AD. Anti-hyperglycemic effects of propolis or Metformin in type 2 diabetes mellitus. International Journal for Vitamin and Nutrition Research; 2022.
Afsharpour F, Hashemipour S, Khadem-Haghighian H, Koushan Y. Effects of Iranian propolis on glycemic status, inflammatory factors, and liver enzyme levels in type 2 diabetic patients: a randomized, double-blind, placebo-controlled, clinical trial. J Nutritional Sci Dietetics. 2017:9–14.
Moayedi F, Taghian F, Jalali Dehkordi K, Hosseini SA. Cumulative effects of exercise training and consumption of propolis on managing diabetic dyslipidemia in adult women: a single-blind, randomized, controlled trial with pre–post-intervention assessments. J Physiological Sci. 2023;73(1):17.
Samadi N, Mozaffari-Khosravi H, Rahmanian M, Askarishahi M. Effects of bee propolis supplementation on glycemic control, lipid profile and insulin resistance indices in patients with type 2 diabetes: a randomized, double-blind clinical trial. J Integr Med. 2017;15(2):124–34.
Karimian J, Hadi A, Pourmasoumi M, Najafgholizadeh A, Ghavami A. The efficacy of propolis on markers of glycemic control in adults with type 2 diabetes mellitus: A systematic review and meta-analysis. Phytother Res. 2019;33(6):1616–26.
Hallajzadeh J, Milajerdi A, Amirani E, Attari VE, Maghsoudi H, Mirhashemi SM. Effects of propolis supplementation on glycemic status, lipid profiles, inflammation and oxidative stress, liver enzymes, and body weight: A systematic review and meta-analysis of randomized controlled clinical trials. J Diabetes Metabolic Disorders. 2021;20:831–43.
Kang LJ, Lee HB, Bae HJ, Lee SG. Antidiabetic effect of propolis: reduction of expression of glucose-6‐phosphatase through Inhibition of Y279 and Y216 autophosphorylation of GSK‐3α/β in HepG2 cells. Phytother Res. 2010;24(10):1554–61.
Ueda M, Hayashibara K, Ashida H. Propolis extract promotes translocation of glucose transporter 4 and glucose uptake through both PI3K-and AMPK‐dependent pathways in skeletal muscle. BioFactors. 2013;39(4):457–66.
Mujica V, Orrego R, Pérez J, Romero P, Ovalle P, Zúñiga-Hernández J, et al. The role of propolis in oxidative stress and lipid metabolism: a randomized controlled trial. Evidence-Based Complement Altern Med. 2017;2017(1):4272940.
Pahlavani N, Malekahmadi M, Firouzi S, Rostami D, Sedaghat A, Moghaddam AB, et al. Molecular and cellular mechanisms of the effects of Propolis in inflammation, oxidative stress and glycemic control in chronic diseases. Nutr Metabolism. 2020;17:1–12.
Salehi-Sahlabadi A, Chhabra M, Rahmani J, Momeni A, Karam G, Nattagh-Eshtivani E, et al. The effect of propolis on anthropometric indices and lipid profile: A systematic review and meta-analysis of randomized controlled trials. J Diabetes Metabolic Disorders. 2020;19:1835–43.
Comments (0)