Anca Adam-Raileanu, Lorenza Forna, Gabriela Stoleriu, Elena Jechel, Ana Maria Laura Buga, Leonard Pertea, Alice Azoicai, Manuel Florin Rosu, Alin Horatiu Nedelcu

DOI : 10.62610/RJOR.2025.2.17.10

ABSTRACT

Due to growing understanding and awareness among medical practitioners as well as the extensive use of novel sensitive and specific diagnostic tests for celiac disease, its prevalence has rose dramatically throughout the past thirty years. However, up to 95% of celiac patients remain undiagnosed as its symptomatology acquired more often extra-digestive features.

Celiac disease is associated with an increased risk of developing several mental health problems in both children and adults, a decline in the quality of life and the need to mentally adapt to a chronic health condition. Consequently, within this review, we highlight the importance of screening for mental health diseases and psychosocial events as a vital component of celiac patients’ clinical approach Without question, due to the significant psychological and economic burden associated with this condition, it is necessary to gain a deeper comprehension of the intricate pathophysiological mechanisms that can shed light on the connection between psychiatric disorders and pediatric celiac disease, in order to assure an appropriate management of the patient. Nevertheless, we explore the potential of a gluten free diet as a therapeutic intervention not only for celiac disease itself, but for alleviating psychiatric symptoms in association to providing psychological support.