Hilkens NA, Casolla B, Leung TW, de Leeuw F-E (2024) Stroke. Lancet Lond Engl 403:2820–2836. https://doi.org/10.1016/S0140-6736(24)00642-1
Powers WJ, Rabinstein AA, Ackerson T, et al (2019) Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. https://doi.org/10.1161/STR.0000000000000211
Berge E, Whiteley W, Audebert H, et al (2021) European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke. Eur Stroke J 6:I–LXII. https://doi.org/10.1177/2396987321989865
Wang C, Yi X, Zhang B et al (2015) Clopidogrel plus aspirin prevents early neurologic deterioration and improves 6-month outcome in patients with acute large artery atherosclerosis stroke. Clin Appl Thromb Off J Int Acad Clin Appl Thromb 21:453–461. https://doi.org/10.1177/1076029614551823
Guo Z-N, Zhang K-J, Zhang P et al (2024) Early tirofiban administration after intravenous thrombolysis in acute ischemic stroke (ADVENT): Study protocol of a multicenter, randomized, double-blind, placebo-controlled clinical trial. Eur Stroke J 9:510–514. https://doi.org/10.1177/23969873231225069
Article PubMed PubMed Central Google Scholar
Liu R, Liang Z, Li W et al (2024) Adding tirofiban on top of recombinant tissue plasminogen activator may improve clinical outcome in acute stroke patients. J Stroke 26:121–124. https://doi.org/10.5853/jos.2023.02250
Article PubMed PubMed Central Google Scholar
Liang Z, Zhang J, Huang S et al (2022) Safety and efficacy of low-dose rt-PA with tirofiban to treat acute non-cardiogenic stroke: a single-center randomized controlled study. BMC Neurol 22:280. https://doi.org/10.1186/s12883-022-02808-w
Article CAS PubMed PubMed Central Google Scholar
Trial Investigators RESCUEBT (2022) Effect of intravenous tirofiban vs placebo before endovascular thrombectomy on functional outcomes in large vessel occlusion stroke: the RESCUE BT randomized clinical trial. JAMA 328:543–553. https://doi.org/10.1001/jama.2022.12584
Jiao Y, Wang X, Guan Y et al (2024) Therapeutic efficacy of tirofiban combined with thrombus aspiration and stent thrombectomy in the treatment of large vessel occlusion ischemic stroke. Neurologist. https://doi.org/10.1097/NRL.0000000000000603
Zhang Y, Zhang Q-Q, Fu C et al (2019) Clinical efficacy of tirofiban combined with a solitaire stent in treating acute ischemic stroke. Braz J Med Biol Res 52:e8396. https://doi.org/10.1590/1414-431X20198396
Article PubMed PubMed Central Google Scholar
Higgins JPT, Thomas J, Chandler J, et al (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.4 (updated August 2023). Cochrane, 2023. Available from www.training.cochrane.org/handbook.
Moher D, Liberati A, Tetzlaff J et al (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 6:e1000097. https://doi.org/10.1371/journal.pmed.1000097
Article PubMed PubMed Central Google Scholar
Zhang Y, Wang J, Ma Z et al (2022) Prospective pilot study of tirofiban in progressive stroke after intravenous thrombolysis. Front Neurol. https://doi.org/10.3389/fneur.2022.982684
Article PubMed PubMed Central Google Scholar
Sterne JAC, Savović J, Page MJ et al (2019) RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ 366:l4898. https://doi.org/10.1136/bmj.l4898
Liu J, Shi Q, Sun Y et al (2019) Efficacy of tirofiban administered at different time points after intravenous thrombolytic therapy with alteplase in patients with acute ischemic stroke. J Stroke Cerebrovasc Dis Off J Natl Stroke Assoc 28:1126–1132. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.12.044
Han B, Ma T, Liu Z et al (2022) Efficacy and safety of tirofiban in clinical patients with acute ischemic stroke. Front Neurol. https://doi.org/10.3389/fneur.2021.785836
Article PubMed PubMed Central Google Scholar
Zi W, Song J, Qiu Z et al (2023) RESCUE BT 2, a multicenter, randomized, double-blind, double-dummy trial of intravenous tirofiban in acute ischemic stroke: Study rationale and design. Int J Stroke Off J Int Stroke Soc 18:620–625. https://doi.org/10.1177/17474930221122681
Zhao W, Li S, Li C et al (2024) Effects of tirofiban on neurological deterioration in patients with acute ischemic stroke: a randomized clinical trial. JAMA Neurol. https://doi.org/10.1001/jamaneurol.2024.0868
Article PubMed PubMed Central Google Scholar
Siebler M, Hennerici MG, Schneider D et al (2011) Safety of tirofiban in acute ischemic stroke. Stroke 42:2388–2392. https://doi.org/10.1161/STROKEAHA.110.599662
Article CAS PubMed Google Scholar
Zhao H, Zhang J, Gu D et al (2017) Tirofiban facilitates the reperfusion process during endovascular thrombectomy in ICAS. Exp Ther Med 14:3314–3318. https://doi.org/10.3892/etm.2017.4856
Article CAS PubMed PubMed Central Google Scholar
Torgano G, Zecca B, Monzani V et al (2010) Effect of intravenous tirofiban and aspirin in reducing short-term and long-term neurologic deficit in patients with ischemic stroke: a double-blind randomized trial. Cerebrovasc Dis 29:275–281. https://doi.org/10.1159/000275503
Article CAS PubMed Google Scholar
Wang K, Huang K, Xia M et al (2024) Clinical efficacy of tirofiban in the endovascular therapy of patients with acute ischaemic stroke due to intracranial atherosclerotic disease: A meta-analysis. Clin Neurol Neurosurg 247:108599. https://doi.org/10.1016/j.clineuro.2024.108599
Sun Z, Huang S, Li W et al (2024) Preoperative and intraoperative tirofiban during endovascular thrombectomy in large vessel occlusion stroke due to large artery atherosclerosis. Eur J Neurol 31:e16419. https://doi.org/10.1111/ene.16419
Article PubMed PubMed Central Google Scholar
Al-Salihi MM, Ayyad A, Al-Jebur MS et al (2023) Safety and efficacy of tirofiban in the management of stroke: A systematic review and meta-analysis of randomized controlled trials. Clin Neurol Neurosurg 232:107867. https://doi.org/10.1016/j.clineuro.2023.107867
Nakagawara J, Minematsu K, Okada Y et al (2010) Thrombolysis with 0.6 mg/kg intravenous alteplase for acute ischemic stroke in routine clinical practice: the Japan post-Marketing Alteplase Registration Study (J-MARS). Stroke 41:1984–1989. https://doi.org/10.1161/STROKEAHA.110.589606
Article CAS PubMed Google Scholar
Kim BJ, Han M-K, Park TH et al (2015) Low-versus standard-dose alteplase for ischemic strokes within 4.5 hours. Stroke 46:2541–2548. https://doi.org/10.1161/STROKEAHA.115.010180
Comments (0)