Giladi N, McDermott MP, Fahn S, Przedborski S, Jankovic J, Stern M, Tanner C (2001) Freezing of gait in PD: Prospective assessment in the DATATOP cohort. Neurology 56(12):1712–1721. https://doi.org/10.1212/WNL.56.12.1712

Article  CAS  PubMed  Google Scholar 

Bloem BR, Hausdorff JM, Visser JE, Giladi N (2004) Falls and freezing of gait in Parkinson’s disease: a review of two interconnected, episodic phenomena. Mov Disord 19(8):871–884. https://doi.org/10.1002/MDS.20115

Article  PubMed  Google Scholar 

Macht M, Kaussner Y, Möller JC, Stiasny-Kolster K, Eggert KM, Krüger H-P, Ellgring H (2007) Predictors of freezing in Parkinson’s disease: a survey of 6,620 patients. Mov Disord 22(7):953–956. https://doi.org/10.1002/mds.21458

Article  PubMed  Google Scholar 

Nutt JG, Bloem BR, Giladi N, Hallett M, Horak FB, Nieuwboer A (2011) Freezing of gait: moving forward on a mysterious clinical phenomenon. Lancet Neurol 10(8):734–744. https://doi.org/10.1016/S1474-4422(11)70143-0

Article  PubMed  PubMed Central  Google Scholar 

Weiss D, Schoellmann A, Fox MD, Bohnen NI, Factor SA, Nieuwboer A, Hallett M, Lewis SJG (2020) Freezing of gait: understanding the complexity of an enigmatic phenomenon. Brain 143(1):14–30. https://doi.org/10.1093/brain/awz314. (Erratum in (2020) Brain 143(3):e24. 10.1093/brain/awaa007)

Article  PubMed  Google Scholar 

Cui CK, Lewis SJG (2021) Future therapeutic strategies for freezing of gait in Parkinson’s disease. Front Hum Neurosci 15:741918. https://doi.org/10.3389/fnhum.2021.741918

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lewis SJG, Factor S, Giladi N, Nieuwboer A, Nutt J, Hallett M (2022) Stepping up to meet the challenge of freezing of gait in Parkinson’s disease. Transl Neurodegener 11:23. https://doi.org/10.1186/s40035-022-00298-x

Article  PubMed  PubMed Central  Google Scholar 

Landes RD, Glover A, Pillai L, Doerhoff S, Virmani T (2022) Levodopa ONOFF-state freezing of gait: defining the gait and non-motor phenotype. PLoS ONE 17(6):e0269227. https://doi.org/10.1371/journal.pone.0269227

Article  CAS  PubMed  PubMed Central  Google Scholar 

Forsaa EB, Larsen JP, Wentzel-Larsen T, Alves G (2015) A 12-year population-based study of freezing of gait in Parkinson’s disease. Parkinsonism Relat Disord 21(3):254–258. https://doi.org/10.1016/J.PARKRELDIS.2014.12.020

Article  CAS  PubMed  Google Scholar 

Nonnekes J, Snijders AH, Nutt JG, Deuschl G, Giladi N, Bloem BR (2015) Freezing of gait: a practical approach to management. Lancet Neurol 14(7):768–778. https://doi.org/10.1016/S1474-4422(15)00041-1

Article  PubMed  Google Scholar 

Lewis SJG, Barker RA (2009) A pathophysiological model of freezing of gait in Parkinson’s disease. Parkinsonism Relat Disord 15(5):333–338. https://doi.org/10.1016/j.parkreldis.2008.08.006

Article  PubMed  Google Scholar 

Shine JM, Naismith SL, Lewis SJG (2011) The pathophysiological mechanisms underlying freezing of gait in Parkinson’s Disease. J Clin Neurosci 18(9):1154–1157. https://doi.org/10.1016/j.jocn.2011.02.007

Article  CAS  PubMed  Google Scholar 

Ehgoetz Martens KA, Hall JM, Georgiades MJ, Gilat M, Walton CC, Matar E, Lewis SJG, Shine JM (2018) The functional network signature of heterogeneity in freezing of gait. Brain 141(4):1145–1160. https://doi.org/10.1093/brain/awy019

Article  PubMed  Google Scholar 

Ehgoetz Martens KA, Lukasik EL, Georgiades MJ, Gilat M, Hall JM, Walton CC, Lewis SJG (2018) Predicting the onset of freezing of gait: a longitudinal study. Mov Disord 33(1):128–135. https://doi.org/10.1002/MDS.27208

Article  PubMed  Google Scholar 

Zhang H, Yin X, Ouyang Z, Chen J, Zhou S, Zhang C, Pan X, Wang S, Yang J, Feng Y, Yu P, Zhang Q (2016) A prospective study of freezing of gait with early Parkinson disease in Chinese patients. Medicine 95(26):e4056. https://doi.org/10.1097/MD.0000000000004056

Article  PubMed  PubMed Central  Google Scholar 

Ou R, Wei Q, Cao B, Song W, Hou Y, Liu H, Yuan X, Zhao B, Wu Y, Shang H (2018) Predictors of freezing of gait in Chinese patients with Parkinson’s disease. Brain Behav 8(3):e00931. https://doi.org/10.1002/brb3.931

Article  PubMed  PubMed Central  Google Scholar 

Herman T, Shema-Shiratzky S, Arie L, Giladi N, Hausdorff JM (2019) Depressive symptoms may increase the risk of the future development of freezing of gait in patients with Parkinson’s disease: findings from a 5-year prospective study. Parkinsonism Relat Disord 60:98–104. https://doi.org/10.1016/j.parkreldis.2018.09.013

Article  PubMed  Google Scholar 

Zhao J, Wan Y, Song L, Wu N, Zhang Z, Liu Z, Gan J (2022) Longitudinal prediction of freezing of gait in Parkinson’s disease: a prospective cohort study. Front Neurol 12:758580. https://doi.org/10.3389/fneur.2021.758580

Article  PubMed  PubMed Central  Google Scholar 

Banks SJ, Bayram E, Shan G, LaBelle DR, Bluett B (2019) Non-motor predictors of freezing of gait in Parkinson’s disease. Gait Posture 68:311–316. https://doi.org/10.1016/J.GAITPOST.2018.12.009

Article  PubMed  Google Scholar 

Ehgoetz Martens KA, Ellard CG, Almeida QJ (2014) Does anxiety cause freezing of gait in Parkinson’s disease? PLoS ONE 9(9):e106561. https://doi.org/10.1371/journal.pone.0106561

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ehgoetz Martens KA, Silveira CRA, Intzandt BN, Almeida QJ (2018) Overload from anxiety: a non-motor cause for gait impairments in Parkinson’s disease. J Neuropsychiatry Clin Neurosci 30(1):77–80. https://doi.org/10.1176/appi.neuropsych.16110298

Article  PubMed  Google Scholar 

Lieberman A (2006) Are freezing of gait (FOG) and panic related? J Neurol Sci 248(1–2):219–222. https://doi.org/10.1016/j.jns.2006.05.023

Article  PubMed  Google Scholar 

Wang F, Pan Y, Zhang M, Hu K (2022) Predicting the onset of freezing of gait in Parkinson’s disease. BMC Neurol. https://doi.org/10.1186/s12883-022-02713-2

Article  PubMed  PubMed Central  Google Scholar 

Farhan SMK, Bartha R, Black SE, Corbett D, Finger E, Freedman M, Greenberg B, Grimes DA, Hegele RA, Hudson C, Kleinstiver PW, Lang AE, Masellis M, McIlroy WE, McLaughlin PM, Montero-Odasso M, Munoz DG, Munoz DP, Strother S, Swartz RH, Symons S, Tartaglia MC, Zinman L, Investigators ONDRI, Strong MJ (2017) The Ontario neurodegenerative disease research initiative (ONDRI). Can J Neurol Sci 44(2):196–202. https://doi.org/10.1017/cjn.2016.415

Article  PubMed  Google Scholar 

Giladi N, Shabtai H, Simon ES, Biran S, Tal J, Korczyn AD (2000) Construction of freezing of gait questionnaire for patients with Parkinsonism. Parkinsonism Relat Disord 6(3):165–170. https://doi.org/10.1016/S1353-8020(99)00062-0

Article  CAS  PubMed  Google Scholar 

Goetz CG, Tilley BC, Shaftman SR, Stebbins GT, Fahn S, Martinez-Martin P, Poewe W, Sampaio C, Stern MB, Dodel R, Dubois B, Holloway R, Jankovic J, Kulisevsky J, Lang AE, Lees A, Leurgans S, LeWitt PA, Nyenhuis D, Olanow CW, Rascol O, Schrag A, Teresi JA, van Hilten JJ, LaPelle N (2008) Movement disorder society-sponsored revision of the unified Parkinson’s disease rating scale (MDS-UPDRS): scale presentation and clinimetric testing results. Mov Disord 23(15):2129–2170. https://doi.org/10.1002/mds.22340

Article  PubMed  Google Scholar 

Stebbins GT, Goetz CG, Burn DJ, Jankovic J, Khoo TK, Tilley BC (2013) How to identify tremor dominant and postural instability/gait difficulty groups with the movement disorder society unified Parkinson’s disease rating scale: comparison with the unified Parkinson’s disease rating scale. Mov Disord 28(5):668–670. https://doi.org/10.1002/mds.25383

Article  PubMed  Google Scholar 

Spitzer RL, Kroenke K, Williams JBW, Löwe B (2006) A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med 166(10):1092–1097. https://doi.org/10.1001/archinte.166.10.1092

Article  PubMed  Google Scholar