Hersh AL, Stefanick ML, Stafford RS. National use of postmenopausal hormone therapy: annual trends and response to recent evidence. JAMA. 2004;291(1):47–53.
Article PubMed CAS Google Scholar
Beral V, Banks E, Reeves G, Bull D. Breast cancer and hormone-replacement therapy: the million women study. Lancet. 2003;362(9392):1330–1.
Støer NC, Vangen S, Singh D, Fortner RT, Hofvind S, Ursin G, et al. Menopausal hormone therapy and breast cancer risk: a population-based cohort study of 1.3 million women in Norway. Br J Cancer. 2024;131(1):126–37.
Article PubMed PubMed Central Google Scholar
Collaborative Group on Hormonal Factors in Breast C. Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence. Lancet. 2019;394(10204):1159–68.
Beral V, Peto R, Pirie K, Reeves G. Menopausal hormone therapy and 20-year breast cancer mortality. Lancet. 2019;394(10204):1139.
Anderson GL, Chlebowsk RT, Aragaki AK, Kuller LH, et al. Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: extended follow-up of the Women’s Health Initiative randomised placebo-controlled trial. Lancet Oncol. 2012;13(5):476–86.
Article PubMed PubMed Central CAS Google Scholar
Chlebowski RT, Anderson GL, Aragaki AK, Manson JE, Stefanick ML, Pan K, et al. Association of menopausal hormone therapy with breast Cancer incidence and mortality during Long-Term follow-up of the women’s Health Initiative Randomized clinical trials. JAMA. 2020;324(4):369–80.
Article PubMed PubMed Central CAS Google Scholar
Chlebowski RT, Anderson GL, Gass M, Lane DS, Aragaki AK, Kuller LH, et al. Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA. 2010;304(15):1684–92.
Article PubMed PubMed Central CAS Google Scholar
Pinkerton JV. Hormone therapy for Postmenopausal Women. N Engl J Med. 2020;382(5):446–55.
Crandall CJ, Mehta JM, Manson JE. Management of Menopausal Symptoms: A Review. Jama. 2023;329(5):405–20.
Article PubMed CAS Google Scholar
Faubion SS, Crandall CJ, Davis L, et al. The 2022 hormone therapy position statement of The North American. Menopause Soc Menopause. 2022;29(7):767–94.
Lederman S, Ottery FD, Cano A, Santoro N, Shapiro M, Stute P, et al. Fezolinetant for treatment of moderate-to-severe vasomotor symptoms associated with menopause (SKYLIGHT 1): a phase 3 randomised controlled study. Lancet. 2023;401(10382):1091–102.
Article PubMed CAS Google Scholar
Pinkerton JV, Simon JA, Joffe H, Maki PM, Nappi RE, Panay N, et al. Elinzanetant for the Treatment of Vasomotor Symptoms Associated With Menopause: OASIS 1 and 2 Randomized Clinical Trials. JAMA. 2024;332(16):1343–54.
Article PubMed CAS Google Scholar
Faubion SS, Shufelt CL, Stefanick ML, Stafford RS. A New Era in Menopause Management? JAMA. 2004;332(16):1335.
Anderson GL, Chlebowski RT, Aragaki AK, Kuller LH, Manson JE, Gass M, et al. Effects of estrogen plus progestin on gynecologic cancers and associated diagnostic procedures: the Women’s Health Initiative randomized trial. JAMA. 2012;290(13):1739–48.
Rich-Edwards JW, Corsano KA, Stampfer MJ. Test of the National Death Index and Equifax Nationwide Death Search. Am J Epidemiol. 1994;140(11):1016–9.
Article PubMed CAS Google Scholar
Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women’s Health Initiative randomized controlled trial. JAMA. 2002;288(3):321–33.
Article PubMed CAS Google Scholar
Anderson GL, Limacher M, Assaf AR, Bassford T, Beresford SA, Black H, et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the women’s Health Initiative randomized controlled trial. JAMA. 2004;291(14):1701–12.
Article PubMed CAS Google Scholar
Chlebowski RT, Anderson G, Manson JE, Pettinger M, Yasmeen S, Lane D, et al. Estrogen alone in postmenopausal women and breast cancer detection by means of mammography and breast biopsy. J Clin Oncol. 2010;28(16):2690–7.
Article PubMed PubMed Central Google Scholar
Dauphine C, Moazzez A, Neal JC, Chlebowski RT, Ozao-Choy J. Single hormone receptor-positive breast cancers have distinct characteristics and survival. Ann Surg Oncol. 2020;27(12):4687–94.
Chlebowski RT, Aragaki AK, Pan K, Haque R, Rohan TE, Song M, et al. Menopausal Hormone Therapy and Ovarian and Endometrial Cancers: Long-Term Follow-Up of the Women’s Health Initiative Randomized Trials. J Clin Oncol 2024 Aug. 2024;42(30):3537–49.
McTiernan A, Martin CF, Peck JD, Aragaki AK, Chlebowski RT, Pisano ED, et al. Estrogen-plus-progestin use and mammographic density in postmenopausal women: women’s Health Initiative randomized trial. J Natl Cancer Inst. 2005;97(18):1366–76.
Article PubMed CAS Google Scholar
Chlebowski RT, Anderson G, Pettinger M, Lane D, Langer RD, Gilligan MA, et al. Estrogen plus progestin and breast cancer detection by means of mammography and breast biopsy. Arch Intern Med. 2008;168(4):370–7. quiz 45.
Article PubMed CAS Google Scholar
Manson JE, Aragaki AK, Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, et al. Menopausal hormone therapy and long-term all-cause and cause-specific mortality: the women’s. Health Initiative Randomized Trials JAMA. 2017;318(10):927–38.
Pan K, Lavasani S, Aragaki AK, Chlebowski RT. Estrogen therapy and breast cancer in randomized clinical trials: a narrative review. Menopause. 2022;29(9):1086–92.
Chlebowski R, Aragaki AK, Pan K, Mortimer JE, Johnson KC, Wactawski-Wende J, et al. Randomized trials of estrogen-alone and breast cancer incidence: a meta-analysis. Breast Cancer Res Treat. 2024;206(1):177–84.
Article PubMed CAS Google Scholar
Harman SM, Brinton EA, Cedars M, Lobo R, Manson JE, Merriam GR, et al. KEEPS: the Kronos Early Estrogen Prevention Study. Climacteric. 2005;8(1):3–12.
Article PubMed CAS Google Scholar
Prentice RL, Aragaki AK, Chlebowski RT, Rossouw JE, Anderson GL, Stefanick ML, et al. Randomized trial evaluation of the benefits and risks of menopausal hormone therapy among women 50–59 years of age. Am J Epidemiol. 2021;190(3):365–75.
Chlebowski RT, Hendrix SL, Langer RD, Stefanick ML, Gass M, Lane D, et al. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the women’s Health Initiative Randomized Trial. JAMA. 2003;289(24):3243–53.
Article PubMed CAS Google Scholar
Vickers MR, MacLennan AH, Lawton B, Ford D, Martin J, Meredith SK, et al. Main morbidities recorded in the women’s international study of long duration oestrogen after menopause (WISDOM): a randomised controlled trial of hormone replacement therapy in postmenopausal women. BMJ. 2007;335(7613):239.
Article PubMed PubMed Central CAS Google Scholar
Bluming AZ, Tavris C. Hormone replacement therapy: real concerns and false alarms. Cancer J. 2009;15(2):93–104.
Tan DA, Dayu ARB. Menopausal hormone therapy: why we should no longer be afraid of the breast cancer risk. Climacteric. 2022;25(4):362–8.
Article PubMed CAS Google Scholar
Chlebowski RT, Aragaki AK. Long-term breast cancer incidence trends by mammography, obesity, and menopausal hormone therapy. Breast Cancer Res Treat. 2024;203(1):121–4.
Comments (0)