Al-Suhaimi E, Aljafary M, Alkhulaifi F (2021) Thymus gland: a double edge sword for coronaviruses. Vaccines 9:1119. https://doi.org/10.3390/vaccines9101119

Article  CAS  PubMed  PubMed Central  Google Scholar 

Antachopoulos C, Katragkou A, Roilides E (2012) Immunotherapy against invasive mold infections. Immunother 4:107–120. https://doi.org/10.2217/imt.11.159

Article  CAS  Google Scholar 

Artym J, Zimecki M (2021) Tymozyna i inne hormony grasicze—mechanizm działania, właściwości i zastosowanie kliniczne [Thymosin and other thymic hormones—mechanism of action, properties and clinical application]. Medycyna Funkcjonalna i Estetyka Lekarska 1:300–318

Google Scholar 

Artym J, Zimecki M (2022) An overview on immunological activity of calf thymus extract (TFX®) and its therapeutic benefits. J Biomed Res Ther. 1:2–20. https://doi.org/10.53156/JZYE7166

Article  Google Scholar 

Audhya T, Scheid MP, Goldstein G (1984) Contrasting biological activities of thymopoietin and splenin, two closely related polypeptide products of thymus and spleen. Proc Natl Acad Sci U S A 81:2847–2849. https://doi.org/10.1073/pnas.81.9.2847

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bach JF (1983) 6 Thymulin (FTS-Zn). Clin Immunol Allergy 3(1):133–156. https://doi.org/10.1016/S0260-4639(22)00263-8

Article  CAS  Google Scholar 

Bach JF, Dardenne M, Pleau JM (1975) Isolation, biochemical characteristics, and biological activity of a circulating thymic hormone in the mouse and in the human. Ann N Y Acad Sci 249:186–210. https://doi.org/10.1111/j.1749-6632.1975.tb29068.x

Article  CAS  PubMed  Google Scholar 

Bach J, Bach M, Charreire J et al (1979) The mode of action of thymic hormones. Ann N Y Acad Sci 332:23–32. https://doi.org/10.1111/j.1749-6632.1979.tb47094.x

Article  CAS  PubMed  Google Scholar 

Badamchian M, Damavandy AA et al (2007) Identification and quantification of thymosin β4 in human saliva and tears. Ann N Y Acad Sci 1112:458–465. https://doi.org/10.1196/annals.1415.046

Article  CAS  PubMed  Google Scholar 

Barrett DJ, Wara DW, Ammann AJ et al (1980) Thymosin therapy in the DiGeorge syndrome. J Pediatr 97:66–71. https://doi.org/10.1016/S0022-3476(80)80132-6

Article  CAS  PubMed  Google Scholar 

Belizário JE, Brandão W, Rossato C et al (2016) Thymic and postthymic regulation of Naïve CD4(+) T-cell lineage fates in humans and mice models. Mediators Inflamm 2016:9523628. https://doi.org/10.1155/2016/9523628

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bene MC, Faure G, Bordigoni P et al (1982) In vitro induction of monoclonal antibody-defined T-cell markers in lymphocytes from immunodeficient children by synthetic serum thymic factor (FTS). Clin Exp Immunol 48:423–428

CAS  PubMed  PubMed Central  Google Scholar 

Blain EJ, Mason DJ, Duance VC (2002) The effect of thymosin beta4 on articular cartilage chondrocyte matrix metalloproteinase expression. Biochem Soc Trans 30:879–882. https://doi.org/10.1042/bst0300879

Article  CAS  PubMed  Google Scholar 

Bock-Marquette I, Maar K, Maar S et al (2023) Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies. Int Immunopharmacol 116:109741. https://doi.org/10.1016/j.intimp.2023.109741

Article  CAS  PubMed  Google Scholar 

Brown MA, Su MA (2019) An inconvenient variable: sex hormones and their impact on T cell responses. J Immunol 202:1927–1933. https://doi.org/10.4049/jimmunol.1801403

Article  CAS  PubMed  Google Scholar 

Brown OA, Sosa YE, Bolognani F et al (1988) Thymulin stimulates prolactin and thyrotropin release in an age-related manner. Mech Ageing Dev 104:249–262. https://doi.org/10.1016/S0047-6374(98)00072-4

Article  Google Scholar 

Brown OA, Sosa YE, Dardenne M et al (2000) Studies on the gonadotropin-releasing activity of thymulin: changes with age. J Gerontol A Biol Sci Med Sci 55:B170–B176. https://doi.org/10.1093/gerona/55.4.B170

Article  CAS  PubMed  Google Scholar 

Camerini R, Garaci E (2015) Historical review of thymosin α 1 in infectious diseases. Expert Opin Biol Ther 15:117–127. https://doi.org/10.1517/14712598.2015.1033393

Article  CAS  Google Scholar 

Carraro G, Naso A, Montomoli E et al (2012) Thymosin-alpha 1 (Zadaxin™) enhances the immunogenicity of an adjuvated pandemic H1N1v influenza vaccine (Focetria™) in hemodialyzed patients: a pilot study. Vaccine 30:1170–1180. https://doi.org/10.1016/j.vaccine.2011.12.014

Article  CAS  PubMed  Google Scholar 

Chandramouli N, Bhargava KK, Incefy GS et al (1986) Solid phase synthesis of thymosin beta 9. Int J Pept Protein Res 28:536–541. https://doi.org/10.1111/j.1399-3011.1986.tb03289.x

Article  CAS  PubMed  Google Scholar 

Chen F, Chen XM, Chen Z et al (2005) Construction and application of a yeast expression system for thymosin a1. Biocell 29:253–259

Article  PubMed  Google Scholar 

Chen Y, Wang A, Zhao L et al (2009) Expression of thymosin 6 alpha1 concatemer in transgenic tomato (Solanum lycopersicum) fruits. Appl Biochem Biotechnol 52:303–312. https://doi.org/10.1042/BA20080054

Article  CAS  Google Scholar 

Cillari E, Milano S, Perego R et al (1992) Modulation of IL-2, IFN-γ, TNF-α and IL-4 production in mice of different ages by thymopentin. Internal J Immunopharmacol 14:1029–1035. https://doi.org/10.1016/0192-0561(92)90147-D

Article  CAS  Google Scholar 

Cordero OJ, Nogueira M, Maurer HR (1997) Novel approaches to immunotherapy using thymic peptides. Immunol Today 18:10–13. https://doi.org/10.1016/S0167-5699(97)80007-2

Article  CAS  PubMed  Google Scholar 

Cordero O, Pineiro A, Nogueira M (1999) Thymic peptides and preparations: an update. Arch Immunol Ther Exp 47:77–82

CAS  Google Scholar 

Costantini C, Bellet MM, Pariano M et al (2019) A reappraisal of thymosin alpha1 in cancer therapy. Front Oncol 9:873. https://doi.org/10.3389/fonc.2019.00873

Article  PubMed  PubMed Central  Google Scholar 

Czarnecki J, Jaskólski B (1978) Preparation TFX-Polfa Jelenia Góra. Arch Immunol Ther Exp 26:475

Google Scholar 

Dąbrowski MP (2006). Grasica, odporność, zdrowie. Podstawy immunokorekcji hormonami grasicy [Thymus, immunity, health: Basics of immunocorrection with thymic hormones]. Wrocław : Triangulum.

Dąbrowski MP, Dąbrowski MI, Stankiewicz W (2011) Review paper the thymus in neuro-endocrine-immune network. Eur J Immunol 36:188–192

Google Scholar 

Danielli R, Cisternino F, Giannarelli D et al (2018) Long-term follow up of metastatic melanoma patients treated with Thymosin alpha-1: investigating immune checkpoints synergy. Expert Opin Biol Ther 18:77–83. https://doi.org/10.1080/14712598.2018.1494717

Article  CAS  PubMed  Google Scholar 

Dardenne M, Papiernik M, Bach JF et al (1974) Studies on thymus products: III. Epithelial origin of the serum thymic factor. Immunology 27:299–304

CAS  PubMed  PubMed Central  Google Scholar 

Dardenne M, Pleau JM, Lefrancier P et al (1981) Role du zinc et d’autres métaux dans l’activité biologique du FTS (thymuline) [role of zinc and other metals in the biological activity of the serum thymic factor (thymulin)]. C R Seances Acad Sci III 292:793–796

CAS  PubMed  Google Scholar 

Davis SL, Safieh-Garabedian B, Khosraviani M (1994) Concentrations of thymulin in unextracted serum from pigs, sheep and cattle as measured by ELISA. J Immunoassay Immunochem 15:191–211. https://doi.org/10.1080/15321819408013947

Article  CAS  Google Scholar 

Dinetz E, Saleeby Y (2023) Borrelia burgdorferi, a root cause of inflammatory bowel disease: a case report of successful treatment and remission. Altern Ther Health Med 29:86–89