Characterization of primary cilia in different epithelial cells of thyroid gland

Amack JD (2022) Structures and functions of cilia during vertebrate embryo development. Mol Reprod Devel 89:579–596. https://doi.org/10.1002/mrd.23650

Article  CAS  PubMed  Google Scholar 

Colin IM, Denef J-F, Lengelé B et al (2013) Recent insights into the cell biology of thyroid angiofollicular units. Endocr Rev 34:209–238. https://doi.org/10.1210/er.2012-1015

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fernández-Santos JM, Morillo-Bernal J, García-Marín R, et al (2012) Paracrine Regulation of Thyroid-Hormone Synthesis by C Cells. In: Agrawal NK (ed) Thyroid Hormone. InTech

Fernández-Santos JM, Utrilla JC, Vázquez-Román V et al (2019) primary cilium in the human thyrocyte: changes in frequency and length in relation to the functional pathology of the thyroid gland. Thyroid 29:595–606. https://doi.org/10.1089/thy.2018.0401

Article  CAS  PubMed  Google Scholar 

Gérard A-C, Many M-C, Daumerie C et al (2002) Structural changes in the angiofollicular units between active and hypofunctioning follicles align with differences in the epithelial expression of newly discovered proteins involved in iodine transport and organification. J Clin Endocrinol Metab 87:1291–1299. https://doi.org/10.1210/jcem.87.3.8278

Article  PubMed  Google Scholar 

Iwanaga T, Miki T, Takahashi-Iwanaga H (2011) Restricted expression of somatostatin receptor 3 to primary cilia in the pancreatic islets and adenohypophysis of mice. Biomed Res 32:73–81. https://doi.org/10.2220/biomedres.32.73

Article  CAS  PubMed  Google Scholar 

Johansson E, Andersson L, Örnros J et al (2015) Revising the embryonic origin of thyroid C cells. Development. https://doi.org/10.1242/dev.126581

Article  PubMed  PubMed Central  Google Scholar 

Kameda Y (2016) Cellular and molecular events on the development of mammalian thyroid C cells. Dev Dynam 245:323–341. https://doi.org/10.1002/dvdy.24377

Article  CAS  Google Scholar 

Lee J, Yi S, Kang YE et al (2016a) Morphological and functional changes in the thyroid follicles of the aged murine and humans. J Pathol Transl Med 50:426–435. https://doi.org/10.4132/jptm.2016.07.19

Article  PubMed  PubMed Central  Google Scholar 

Lee J, Yi S, Kang YE et al (2016) Defective ciliogenesis in thyroid hürthle cell tumors is associated with increased autophagy. Oncotarget 7:79117–79130. https://doi.org/10.18632/oncotarget.12997

Article  PubMed  PubMed Central  Google Scholar 

Lee J, Yi S, Chang JY et al (2019) Loss of primary cilia results in the development of cancer in the murine thyroid gland. Mol Cells 42:113–122

CAS  PubMed  PubMed Central  Google Scholar 

Lee J, Park KC, Sul HJ et al (2021a) Loss of primary cilia promotes mitochondria-dependent apoptosis in thyroid cancer. Sci Rep 11:4181. https://doi.org/10.1038/s41598-021-83418-3

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee J, Sul HJ, Kim K-H et al (2021b) Primary cilia mediate TSH-regulated thyroglobulin endocytic pathways. Front Endocrinol 12:700083. https://doi.org/10.3389/fendo.2021.700083

Article  Google Scholar 

Li X, Yang S, Deepak V et al (2021) Identification of cilia in different mouse tissues. Cells 10:1623. https://doi.org/10.3390/cells10071623

Article  CAS  PubMed  PubMed Central  Google Scholar 

Martin A, Hedinger C, Häberlin-Jakob M, Walt H (1988) Structure and motility of primary cilia in the follicular epithelium of the human thyroid. Virchows Archiv B Cell Pathol 55:159–166. https://doi.org/10.1007/BF02896572

Article  CAS  Google Scholar 

Martin V, Martin L, Viennet G et al (2000) Ultrastructural features of “‘solid cell nest’” of the human thyroid gland: a study of 8 cases. Ultrastruc Pathol 24:1–8. https://doi.org/10.1080/019131200281255

Article  CAS  Google Scholar 

Nunez EA, Gershon MD (1978) Cytophysiology of thyroid parafollicular cells. Int Rev Cytol 52:1–80. https://doi.org/10.1016/s0074-7696(08)60753-6

Article  CAS  PubMed  Google Scholar 

Qatato M, Venugopalan V, Al-Hashimi A et al (2021) Trace amine-associated receptor 1 trafficking to cilia of thyroid epithelial cells. Cells 10:1518. https://doi.org/10.3390/cells10061518

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ríos Moreno MJ, Galera-Ruiz H, De Miguel M et al (2011) Inmunohistochemical profile of solid cell nest of thyroid gland. Endocr Pathol 22:35–39. https://doi.org/10.1007/s12022-010-9145-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Satir P (2017) CILIA: before and after. Cilia 6:1. https://doi.org/10.1186/s13630-017-0046-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sobrinho-Simões M, Johannessen JV (1981) Scanning electron microscopy of the normal human thyroid. J Submicrosc Cytol 13:209–222

PubMed  Google Scholar 

Spasic M, Jacobs CR (2017) Primary cilia: cell and molecular mechanosensors directing whole tissue function. Semin Cell Dev Biol 71:42–52. https://doi.org/10.1016/j.semcdb.2017.08.036

Article  CAS  PubMed  PubMed Central  Google Scholar 

Spiegel C, Bestetti G, Rossi G, Blum JW (1993) Feeding of rapeseed presscake meal to pigs: effects on thyroid morphology and function and on thyroid hormone blood levels, on liver and on growth performance*. J Vet Med A 40:45–57. https://doi.org/10.1111/j.1439-0442.1993.tb00599.x

Article  CAS  Google Scholar 

Suzuki K, Lavaroni S, Mori A et al (1998) Autoregulation of thyroid-specific gene transcription by thyroglobulin. Proc Natl Acad Sci USA 95(14):8251–8256. https://doi.org/10.1073/pnas.95.14.8251

Article  CAS  PubMed  PubMed Central  Google Scholar 

Suzuki K, Kawashima A, Yoshihara A et al (2011) Role of thyroglobulin on negative feedback autoregulation of thyroid follicular function and growth. J Endocrinol 209:169–174. https://doi.org/10.1530/JOE-10-0486

Article  CAS  PubMed  Google Scholar 

Szumska J, Batool Z, Al-Hashimi A et al (2019) Treatment of rat thyrocytes in vitro with cathepsin B and L inhibitors results in disruption of primary cilia leading to redistribution of the trace amine associated receptor 1 to the endoplasmic reticulum. Biochimie 166:270–285. https://doi.org/10.1016/j.biochi.2019.07.010

Article  CAS  PubMed  Google Scholar 

Utrilla JC, Gordillo-Martínez F, Gómez-Pascual A et al (2015) Comparative study of the primary cilia in thyrocytes of adult mammals. J Anat 227:550–560. https://doi.org/10.1111/joa.12360

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vázquez-Román V, Utrilla JC, Fernández-Santos JM et al (2013) Postnatal fate of the ultimobranchial remnants in the rat thyroid gland. J Morphol 274:725–732. https://doi.org/10.1002/jmor.20126

Article  PubMed  Google Scholar 

Vázquez-Román V, Utrilla JC, Fernández-Santos JM, Martín-Lacave I (2017) Immunohistochemical profiling of the ultimobranchial remnants in the rat postnatal thyroid gland. J Morphol 278:1114–1124. https://doi.org/10.1002/jmor.20698

Article  CAS  PubMed  Google Scholar 

Vázquez-Román V, Cameselle-Teijeiro JM, Fernández-Santos JM et al (2022) Histopathological features of pendred syndrome thyroids align with differences in the expression of thyroid-specific markers, apical iodide transporters, and ciliogenesis process. Endocr Pathol 33:484–493. https://doi.org/10.1007/s12022-022-09732-2

Article  CAS  PubMed  PubMed

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