Ghaffari A, Manafi A, Moghimi HR. Clindamycin phosphate absorption from nanoliposomal formulations through third-degree burn eschar. World J Plast Surg. 2015;4:145.
PubMed PubMed Central Google Scholar
Jeschke MG, van Baar ME, Choudhry MA, Chung KK, Gibran NS, Logsetty S. Burn injury. Nat Rev Dis Primers. 2020;6:11. https://doi.org/10.1038/s41572-020-0145-5.
Article PubMed PubMed Central Google Scholar
Hosseini M, Roberts MS, Aboofazeli R, Moghimi HR. Measurement of Hansen solubility parameters of third-degree burn eschar. Burns. 2022;48:860–71. https://doi.org/10.1016/j.burns.2021.07.017.
Gurfinkel R, Rosenberg L, Cohen S, Cohen A, Barezovsky A, Cagnano E. Histological assessment of tangentially excised burn eschars. Can J Surg. 2010;18:33–6.
Monsuur HN, Van den Broek LJ, Jhingoerie RL, Vloemans AF, Gibbs S. Burn eschar stimulates fibroblast and adipose mesenchymal stromal cell proliferation and migration but inhibits endothelial cell sprouting. Int J Mol Sci. 2017;18:1790. https://doi.org/10.3390/ijms18081790.
Article CAS PubMed PubMed Central Google Scholar
moghimi H, Manafi A. The necessity for enhancing of drugs absorption through burn eschar. Burns. 2009;6. https://doi.org/10.1016/j.burns.2008.09.010.
Cartotto R. Topical antimicrobial agents for pediatric burns. Burns Trauma. 2017;5. https://doi.org/10.1186/s41038-017-0096-6.
Yang P, Yang K, Liu L, Li C, Tao J, Ai F. Fabrication of ultra-small GSH-AgNCs with excellent eschar penetration and antibacterial properties for the healing of burn infection wounds. Res Sq. 2021. https://doi.org/10.21203/rs.3.rs-302056/v1.
Article PubMed PubMed Central Google Scholar
Zadeh BSM, Moghimi H, Santos P, Hadgraft J, Lane ME. A comparative study of the in vitro permeation characteristic of sulphadiazine across synthetic membranes and eschar tissue. Int Wound J. 2008;5:633–8. https://doi.org/10.1111/j.1742-481X.2008.00539.x.
Article PubMed PubMed Central Google Scholar
Ghaffari A, Manafi A, Moghimi HR. Enhancement effect of trypsin on permeation of clindamycin phosphate through third-degree burn eschar. Iran J Pharm Res. 2013;12:3.
CAS PubMed PubMed Central Google Scholar
Moghimi HR, Makhmalzadeh BS, Manafi A. Enhancement effect of terpenes on silver sulphadiazine permeation through third-degree burn eschar. Burns. 2009;35:1165–70. https://doi.org/10.1016/j.burns.2009.02.006.
Manafi A, Hashemlou A, Momeni P, Moghimi HR. Enhancing drugs absorption through third-degree burn wound eschar. Burns. 2008;34:698–702. https://doi.org/10.1016/j.burns.2007.07.018.
Ghaffari A. Application of sonophoresis or combination of sonophoresis with iontophoresis, chemical enhancers, and liposomes for enhancement of permeation of drugs, through third-degree burn eschar, PhD thesis (Supervisor: Moghimi, HR): PhD Thesis (Supervisor: Moghimi, HR). School of Pharmacy, Shahid Beheshti; 2011.
Escobar-Chávez JJ, Bonilla‐Martínez D, Angélica M, Molina‐Trinidad E, Casas‐Alancaster N, Revilla‐Vázquez AL. Microneedles: a valuable physical enhancer to increase transdermal drug delivery. J Clin Pharmacol. 2011;51:964–77. https://doi.org/10.1177/0091270010378859.
Article CAS PubMed Google Scholar
Rzhevskiy AS, Singh TRR, Donnelly RF, Anissimov YG. Microneedles as the technique of drug delivery enhancement in diverse organs and tissues. J Control Release. 2018;270:184–202. https://doi.org/10.1016/j.jconrel.2017.11.048.
Article CAS PubMed Google Scholar
Jung JH, Jin SG. Microneedle for transdermal drug delivery: current trends and fabrication. J Pharm Investig. 2021;1–15. https://doi.org/10.1007/s40005-021-00512-4.
Nguyen HX, Nguyen CN. Microneedle-mediated transdermal delivery of biopharmaceuticals. Pharmaceutics. 2023;15:277. https://doi.org/10.3390/pharmaceutics15010277.
Article CAS PubMed PubMed Central Google Scholar
Sartawi Z, Blackshields C, Faisal W. Dissolving microneedles: applications and growing therapeutic potential. J Control Release. 2022;348:186–205. https://doi.org/10.1016/j.jconrel.2022.05.045.[.
Article CAS PubMed Google Scholar
Daei hamedMG, Moghimi A. The effects of age, gender and anatomical site on the barrier properties of third degree burn eschar toward hydrophilic and lipophilic drugs. Res Pharm Sci. 2012;7:696.
Bennion BJ, Be NA, McNerney MW, Lao V, Carlson EM, Valdez CA. Predicting a drug’s membrane permeability: a computational model validated with in vitro permeability assay data. J Phys Chem B. 2017;121:5228–37. https://doi.org/10.1021/acs.jpcb.7b02914.
Article CAS PubMed Google Scholar
Stahl J, Wohlert M, Kietzmann M. Microneedle pretreatment enhances the percutaneous permeation of hydrophilic compounds with high melting points. BMC Pharmacol amp; Toxicol. 2012;13:1–7. https://doi.org/10.1186/2050-6511-13-5.
Badran M, Kuntsche J, Fahr A. Skin penetration enhancement by a microneedle device (Dermaroller®) in vitro: dependency on needle size and applied formulation. Eur J Pharm Sci. 2009;36:511–23. https://doi.org/10.1016/j.ejps.2008.12.008.
Article CAS PubMed Google Scholar
Frantz K, Byers CG. Thermal injury. Compend Contin Educ Vet. 2011;33:E1–6.
Richard C, Cassel S, Blanzat M. Vesicular systems for dermal and transdermal drug delivery. RSC Adv. 2021;11:442–51. https://doi.org/10.1039/D0RA09561C.
Mortazavi SM, Kobarfard F, Manafi A, Maibach HI, Moghimi HR. Terpene conjugation: a novel approach for topical peptide delivery. J Cosmet Sci. 2021;72.
Najib ON, Kirton SB, Martin GP, Botha MJ, Sallam A-S, Murnane D. Multivariate analytical approaches to identify key molecular properties of vehicles, permeants and membranes that affect permeation through membranes. Pharmaceutics. 2020;12:958. https://doi.org/10.3390/pharmaceutics12100958.
Article CAS PubMed PubMed Central Google Scholar
Mortazavi SM, Moghimi HR, Maibach HI. Chemical modification: An important and feasible method for improving peptide and protein dermal and transdermal delivery. Percutaneous Absorption2021. pp. 459 – 68.
Moghimi HR, Mortazavi SM, Maibach HI. Drug permeation through burn Eschar: possibilities and improvements. Percutaneous Absorption: CRC; 2021. pp. 929–40.
MakhmalZadeh B, Moghimi H. Effect of hydration on barrier performance of third-degree burn eschar. Iran J Pharm Res. 2006. https://doi.org/10.22037/ijpr.2010.670.
Datta D, Panchal DS, Venuganti VVK. Transdermal delivery of Vancomycin hydrochloride: influence of chemical and physical permeation enhancers. Int J Pharm. 2021;602:120663. https://doi.org/10.1016/j.ijpharm.2021.120663.
Dhote V, Bhatnagar P, Mishra PK, Mahajan SC, Mishra DK. Iontophoresis: a potential emergence of a transdermal drug delivery system. Sci Pharm. 2012;80:1–28. https://doi.org/10.3797/scipharm.1108-20.
Article CAS PubMed Google Scholar
Kalluri H, Kolli CS, Banga AK. Characterization of microchannels created by metal microneedles: formation and closure. AAPS J. 2011;13:473–81. https://doi.org/10.1208/s12248-011-9288-3.
Article PubMed PubMed Central Google Scholar
Panzade PS, Iontophoresis. A functional approach for enhancement of transdermal drug delivery. Asian j Biomed Pharm. 2012;2:1.
Nguyen HX, Banga AK. Enhanced skin delivery of vismodegib by microneedle treatment. Drug Deliv Transl Res. 2015;5:407–23. https://doi.org/10.1007/s13346-015-0241-3.
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