Smith EMD, Lythgoe H, Midgley A, Beresford MW, Hedrich CM. Juvenile-onset systemic lupus erythematosus: update on clinical presentation, pathophysiology and treatment options. Clin Immunol. 2019;209: 108274.

Article  CAS  PubMed  Google Scholar 

Silva CA, Avcin T, Brunner HI. Taxonomy for systemic lupus erythematosus with onset before adulthood. Arthritis Care Res (Hoboken). 2012;64(12):1787–93.

Article  PubMed  PubMed Central  Google Scholar 

Ambrose N, Morgan TA, Galloway J, Ionnoau Y, Beresford MW, Isenberg DA, UK JSLE Study Group. Differences in disease phenotype and severity in SLE across age groups. Lupus. 2016;25(14):1542–50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hedrich CM, Smith EM, Beresford MW. Juvenile-onset systemic lupus erythematosus (jSLE)–Pathophysiological concepts and treatment options. Best Pract Res Clin Rheumatol. 2017;31(4):488–504.

Article  PubMed  Google Scholar 

Rees F, Doherty M, Grainge M, Davenport G, Lanyon P, Zhang W. The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012. Ann Rheum Dis. 2016;75(1):136–41.

Article  PubMed  Google Scholar 

Muscal E, Brey RL. Neurologic manifestations of systemic lupus erythematosus in children and adults. Neurol Clin. 2010;28(1):61–73.

Article  PubMed  PubMed Central  Google Scholar 

Giani T, Smith EM, Al-Abadi E, Armon K, Bailey K, Ciurtin C, et al. Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: data from the UK Juvenile-onset systemic lupus erythematosus cohort study. Lupus. 2021;30(12):1955–65.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Unterman A, Nolte JE, Boaz M, Abady M, Shoenfeld Y, Zandman-Goddard G. Neuropsychiatric syndromes in systemic lupus erythematosus: a meta-analysis. Semin Arthritis Rheum. 2011;41(1):1–11.

Article  PubMed  Google Scholar 

Maritsi D, Al-Obadi M, Melo-Gomes S, Edelsten C, Pilkington C. Systemic lupus erythematosus (SLE) complicated by neuromyelitis optica: case series from a Tertiary Paediatric Rheumatology Centre. Pediatr Res. 2011;70(5):190.

Article  Google Scholar 

Baisya R, Kumar Devarasetti P, Narayanan R, Rajasekhar L. Posterior reversible encephalopathy syndrome in juvenile lupus-a case series and literature review. Lupus. 2022;31(5):606–12.

Article  PubMed  Google Scholar 

Theisen A, Bose P, Knight C, Oliver M. Leukoencephalopathy and cerebral edema as the presenting manifestations of SLE in an ANA-negative adolescent female: a case report and review of literature. Pediatr Rheumatol. 2020;18:1–9.

Article  Google Scholar 

Vina ER, Fang AJ, Wallace DJ, Weisman MH. Chronic inflammatory demyelinating polyneuropathy in patients with systemic lupus erythematosus: prognosis and outcome. Semin Arthritis Rheum. 2005;35(3):175–84.

Article  CAS  PubMed  Google Scholar 

Singh S, Gupta MK, Ahluwalia J, Singh P, Malhi P. Neuropsychiatric manifestations and antiphospholipid antibodies in pediatric onset lupus: 14 years of experience from a tertiary center of North India. Rheumatol Int. 2009;29(12):1455–61.

Article  CAS  PubMed  Google Scholar 

Kısaarslan AP, Çiçek S, Batu ED, Şahin S, Gürgöze MK, Çetinkaya SB, et al. Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: a multicenter study. Jt Bone Spine. 2023;90(4): 105559.

Article  Google Scholar 

Ambrose N, Morgan T, Galloway J, Ionnoau Y, Beresford M, Isenberg D. Differences in disease phenotype and severity in SLE across age groups. Lupus. 2016;25(14):1542–50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Amaral B, Murphy G, Ioannou Y, Isenberg DA. A comparison of the outcome of adolescent and adult-onset systemic lupus erythematosus. Rheumatology. 2014;53(6):1130–5.

Article  PubMed  Google Scholar 

Choi J, Park D, Kang J, Yim Y, Lee K, Lee J, et al. Comparison of clinical and serological differences among juvenile-, adult-, and late-onset systemic lupus erythematosus in Korean patients. Lupus. 2015;24(12):1342–9.

Article  CAS  PubMed  Google Scholar 

Govoni M, Hanly JG. The management of neuropsychiatric lupus in the 21st century: still so many unmet needs? Rheumatology. 2020;59(Supplement 5):v52–62.

Article  PubMed  PubMed Central  Google Scholar 

Hanly JG, McCurdy G, Fougere L, Douglas J-A, Thompson K. Neuropsychiatric events in systemic lupus erythematosus: attribution and clinical significance. J Rheumatol. 2004;31(11):2156–62.

PubMed  Google Scholar 

Tucker L, Uribe A, Fernandez M, Vila L, McGwin G, Apte M, et al. Adolescent onset of lupus results in more aggressive disease and worse outcomes: results of a nested matched case–control study within LUMINA, a multiethnic US cohort (LUMINA LVII). Lupus. 2008;17(4):314–22.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Torrente-Segarra V, Salman Monte TC, Rúa-Figueroa I, Sánchez-Alonso F, López-Longo FJ, Galindo-Izquierdo M, et al. Juvenile-and adult-onset systemic lupus erythematosus: a comparative study in a large cohort from the Spanish Society of Rheumatology Lupus Registry (RELESSER). Clin Exp Rheumatol. 2017;35(6):1047–55.

PubMed  Google Scholar 

Bortoluzzi A, Scire CA, Bombardieri S, Caniatti L, Conti F, De Vita S, et al. Development and validation of a new algorithm for attribution of neuropsychiatric events in systemic lupus erythematosus. Rheumatology. 2015;54(5):891–8.

Article  CAS  PubMed  Google Scholar 

Brunner HI, Gladman DD, Ibañez D, Urowitz MD, Silverman ED. Difference in disease features between childhood-onset and adult-onset systemic lupus erythematosus. Arthritis Rheum. 2008;58(2):556–62.

Article  PubMed  Google Scholar 

Soybilgic A. Neuropsychiatric systemic lupus erythematosus in children. Pediatr Ann. 2015;44(6):e153–8.

Article  PubMed  Google Scholar 

Khajezadeh M-A, Zamani G, Moazzami B, Nagahi Z, Mousavi-Torshizi M, Ziaee V. Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus. Neurol Res Int. 2018;2018:1–7.

Article  Google Scholar 

Yu H, Lee J, Wang L, Yang Y, Chiang BL. Neuropsychiatric manifestations in pediatric systemic lupus erythematosus: a 20-year study. Lupus. 2006;15(10):651–7.

Article  CAS  PubMed  Google Scholar 

Zambrano YCZ, Ramos JDG, Vargas NEP, Ramirez DCB, Rodriguez SMR, Niño ACV, et al. Risk factors for neuropsychiatric manifestations in children with systemic lupus erythematosus: case-control study. Pediatr Neurol. 2014;51(3):403–9.

Article  Google Scholar 

Appenzeller S, Pereira DR, Julio PR, Reis F, Rittner L, Marini R. Neuropsychiatric manifestations in childhood-onset systemic lupus erythematosus. Lancet Child Adolesc Health. 2022;6(8):571–81.

Article  PubMed  Google Scholar 

Santos FPST, Nascimento BR, Calderaro DC, Ferreira GA, Correa H. Neuropsychiatric syndromes in childhood-onset systemic lupus erythematosus: a systematic review and meta-analysis. JCR J Clin Rheumatol. 2021;27(5):206–14.

Article  PubMed  Google Scholar 

Harel L, Sandborg C, Lee T, von Scheven E. Neuropsychiatric manifestations in pediatric systemic lupus erythematosus and association with antiphospholipid antibodies. J Rheumatol. 2006;33(9):1873–7.

CAS  PubMed  Google Scholar 

Lim LSH, Lefebvre A, Benseler S, Peralta M, Silverman ED. Psychiatric illness of systemic lupus erythematosus in childhood: spectrum of clinically important manifestations. J Rheumatol. 2013;40(4):506–12.

Article  PubMed  Google Scholar 

Olfat MO, Al-Mayouf SM, Muzaffer MA. Pattern of neuropsychiatric manifestations and outcome in juvenile systemic lupus erythematosus. Clin Rheumatol. 2004;23:395–9.

Article  PubMed  Google Scholar 

Abu-Arafeh I, Razak S, Sivaraman B, Graham C. Prevalence of headache and migraine in children and adolescents: a systematic review of population-based studies. Dev Med Child Neurol. 2010;52(12):1088–97.

Article  PubMed