Hutson TH, Di Giovanni S. The translational landscape in spinal cord injury: focus on neuroplasticity and regeneration. Nat Rev Neurol. 2019;15(12):732–45.
Li C, Li X, Zhao B, Wang C. Exosomes derived from miR-544-modified mesenchymal stem cells promote recovery after spinal cord injury. Arch Physiol Biochem. 2020;126(4):369–75.
Article CAS PubMed Google Scholar
Furlan JC, Craven BC, Fehlings MG. Surgical management of the elderly with traumatic cervical spinal cord injury: a cost-utility analysis. Neurosurgery. 2016;79(3):418–25.
Bal S, Landau HJ. Solid organ transplantation. Hematol Oncol Clin North Am. 2020;34(6):1161–75.
Vanholder R, Dominguez-Gil B, Busic M, Cortez-Pinto H, Craig JC, Jager KJ, et al. Organ donation and transplantation: a multi-stakeholder call to action. Nat Rev Nephrol. 2021;17(8):554–68.
Article PubMed PubMed Central Google Scholar
Hoogduijn MJ, Issa F, Casiraghi F, Reinders MEJ. Cellular therapies in organ transplantation. Transpl Int. 2021;34(2):233–44.
Hu XC, Lu YB, Yang YN, Kang XW, Wang YG, Ma B, et al. Progress in clinical trials of cell transplantation for the treatment of spinal cord injury: how many questions remain unanswered? Neural Regen Res. 2021;16(3):405–13.
Yamazaki K, Kawabori M, Seki T, Houkin K. Clinical trials of stem cell treatment for spinal cord injury. Int J Mol Sci. 2020;21(11):3994.
Article CAS PubMed PubMed Central Google Scholar
Yang Y, Pang M, Du C, Liu ZY, Chen ZH, Wang NX, et al. Repeated subarachnoid administrations of allogeneic human umbilical cord mesenchymal stem cells for spinal cord injury: a phase 1/2 pilot study. Cytotherapy. 2021;23(1):57–64.
Article CAS PubMed Google Scholar
Marino L, Castaldi MA, Rosamilio R, Ragni E, Vitolo R, Fulgione C, et al. Mesenchymal stem cells from the Wharton’s Jelly of the human umbilical cord: biological properties and therapeutic potential. Int J Stem Cells. 2019;12(2):218–26.
Article CAS PubMed PubMed Central Google Scholar
Mushahary D, Spittler A, Kasper C, Weber V, Charwat V. Isolation, cultivation, and characterization of human mesenchymal stem cells. Cytometry A. 2018;93(1):19–31.
Article CAS PubMed Google Scholar
Xie Q, Liu R, Jiang J, Peng J, Yang C, Zhang W, et al. What is the impact of human umbilical cord mesenchymal stem cell transplantation on clinical treatment? Stem Cell Res Ther. 2020;11(1):519.
Article PubMed PubMed Central Google Scholar
Guan YT, Xie Y, Li DS, Zhu YY, Zhang XL, Feng YL, et al. Comparison of biological characteristics of mesenchymal stem cells derived from the human umbilical cord and decidua parietalis. Mol Med Rep. 2019;20(1):633–9.
CAS PubMed PubMed Central Google Scholar
Bharti D, Shivakumar SB, Park JK, Ullah I, Subbarao RB, Park JS, et al. Comparative analysis of human Wharton’s jelly mesenchymal stem cells derived from different parts of the same umbilical cord. Cell Tissue Res. 2018;372(1):51–65.
Article CAS PubMed Google Scholar
Markov A, Thangavelu L, Aravindhan S, Zekiy AO, Jarahian M, Chartrand MS, et al. Mesenchymal stem/stromal cells as a valuable source for the treatment of immune-mediated disorders. Stem Cell Res Ther. 2021;12(1):192.
Article CAS PubMed PubMed Central Google Scholar
Yao J, Zheng J, Cai J, Zeng K, Zhou C, Zhang J, et al. Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate rat hepatic ischemia-reperfusion injury by suppressing oxidative stress and neutrophil inflammatory response. FASEB J. 2019;33(2):1695–710.
Article CAS PubMed Google Scholar
Zhou S, Lei Y, Wang P, Chen J, Zeng L, Qu T, et al. Human umbilical cord mesenchymal stem cells encapsulated with pluronic F-127 enhance the regeneration and angiogenesis of thin endometrium in rat via local IL-1beta stimulation. Stem Cells Int. 2022;2022:7819234.
Article PubMed PubMed Central Google Scholar
Ren X, Zhong W, Li W, Tang M, Zhang K, Zhou F, et al. Human umbilical cord-derived mesenchymal stem cells alleviate psoriasis through TNF-alpha/NF-kappaB/MMP13 pathway. Inflammation. 2023;46(3):987–1001.
Article CAS PubMed Google Scholar
Blot M, Jacquier M, Pauchard LA, Rebaud C, Marlin C, Hamelle C, et al. Adverse mechanical ventilation and pneumococcal pneumonia induce immune and mitochondrial dysfunctions mitigated by mesenchymal stem cells in rabbits. Anesthesiology. 2022;136(2):293–313.
Article CAS PubMed Google Scholar
Chen H, Luo Y, Zhu Y, Ye Y, Chen D, Song X, et al. Enhanced secretion of hepatocyte growth factor in human umbilical cord mesenchymal stem cells ameliorates pulmonary fibrosis induced by bleomycin in rats. Front Pharmacol. 2022;13:1070736.
Article CAS PubMed Google Scholar
Hou L, Zhu Z, Jiang F, Zhao J, Jia Q, Jiang Q, et al. Human umbilical cord mesenchymal stem cell-derived extracellular vesicles alleviated silica induced lung inflammation and fibrosis in mice via circPWWP2A/miR-223-3p/NLRP3 axis. Ecotoxicol Environ Saf. 2023;251:114537.
Article CAS PubMed Google Scholar
Zhou Q, Rong C, Gu T, Li H, Wu L, Zhuansun X, et al. Mesenchymal stem cells improve liver fibrosis and protect hepatocytes by promoting microRNA-148a-5p-mediated inhibition of notch signaling pathway. Stem Cell Res Ther. 2022;13(1):354.
Article CAS PubMed PubMed Central Google Scholar
Wu J, Song D, Li Z, Guo B, Xiao Y, Liu W, et al. Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis. Cell Res. 2020;30(9):794–809.
Article CAS PubMed Google Scholar
Su WH, Wang CJ, Hung YY, Lu CW, Ou CY, Tseng SH, et al. MicroRNA-29a exhibited pro-angiogenic and anti-fibrotic features to intensify human umbilical cord mesenchymal stem cells-renovated perfusion recovery and preventing against fibrosis from skeletal muscle ischemic injury. Int J Mol Sci. 2019;20(23):5859.
Article CAS PubMed PubMed Central Google Scholar
Xu Y, Hong Y, Xu M, Ma K, Fu X, Zhang M, et al. Role of keratinocyte growth factor in the differentiation of sweat gland-like cells from human umbilical cord-derived mesenchymal stem cells. Stem Cells Transl Med. 2016;5(1):106–16.
Article CAS PubMed Google Scholar
Jung N, Kong T, Yu Y, Park H, Lee E, Yoo S, et al. Immunomodulatory effect of epidermal growth factor secreted by human umbilical cord blood-derived mesenchymal stem cells on atopic dermatitis. Int J Stem Cells. 2022;15(3):311–23.
Article CAS PubMed PubMed Central Google Scholar
Xiang E, Han B, Zhang Q, Rao W, Wang Z, Chang C, et al. Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis. Stem Cell Res Ther. 2020;11(1):336.
Article CAS PubMed PubMed Central Google Scholar
Praveen Kumar L, Kandoi S, Misra R, Vijayalakshmi S, Rajagopal K, Verma RS. The mesenchymal stem cell secretome: A new paradigm towards cell-free therapeutic mode in regenerative medicine. Cytokine Growth Factor Rev. 2019;46:1–9.
Ruan ZB, Chen GC, Zhang R, Zhu L. Circular RNA expression profiles during the differentiation of human umbilical cord-derived mesenchymal stem cells into cardiomyocyte-like cells. J Cell Physiol. 2019;234(9):16412–23.
Comments (0)