Hoffman LM, Veldhuijzen van Zanten SEM, Colditz N et al (2018) Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries. J Clin Oncol 36:1963–1972
Article CAS PubMed PubMed Central Google Scholar
Cooney T, Lane A, Bartels U et al (2017) Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study. Neuro Oncol 19:1279–1280
Article PubMed PubMed Central Google Scholar
Hargrave D, Bartels U, Bouffet E (2006) Diffuse brainstem glioma in children: critical review of clinical trials. Lancet Oncol 7:241–248
El-Khouly FE, Veldhuijzen van Zanten SEM, Santa-Maria Lopez V et al (2019) Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand? J Neurooncol 145:177–184
Article PubMed PubMed Central Google Scholar
Panditharatna E, Yaeger K, Kilburn LB, Packer RJ, Nazarian J (2015) Clinicopathology of diffuse intrinsic pontine glioma and its redefined genomic and epigenomic landscape. Cancer Genet 208:367–373
Louis DN, Perry A, Reifenberger G et al (2016) The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol 131:803–820
Louis DN, Perry A, Wesseling P et al (2021) The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol 23:1231–1251
Article CAS PubMed PubMed Central Google Scholar
Leach JL, Roebker J, Schafer A et al (2020) MR imaging features of diffuse intrinsic pontine glioma and relationship to overall survival: report from the International DIPG Registry. Neuro Oncol 22:1647–1657
Article PubMed PubMed Central Google Scholar
Kim HJ, Lee JH, Kim Y et al (2023) Suggestions for escaping the dark ages for pediatric diffuse intrinsic pontine glioma treated with radiotherapy: analysis of prognostic factors from the national multicenter study. Cancer Res Treat 55:41–49
Article CAS PubMed Google Scholar
Poussaint TY, Kocak M, Vajapeyam S et al (2011) MRI as a central component of clinical trials analysis in brainstem glioma: a report from the Pediatric Brain Tumor Consortium (PBTC). Neuro Oncol 13:417–427
Article PubMed PubMed Central Google Scholar
Morana G, Tortora D, Bottoni G et al (2020) Correlation of multimodal (18)F-DOPA PET and conventional MRI with treatment response and survival in children with diffuse intrinsic pontine gliomas. Theranostics 10:11881–11891
Article CAS PubMed PubMed Central Google Scholar
Jackson ER, Duchatel RJ, Staudt DE et al (2023) ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma. Cancer Res. https://doi.org/10.1158/0008-5472.CAN-23-0186:OF1-OF17
Venneti S, Kawakibi AR, Ji S et al (2023) Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways. Cancer Discov 13:2370–2393
Article CAS PubMed Google Scholar
El-Khouly FE, Veldhuijzen van Zanten SEM, Jansen MHA et al (2021) A phase I/II study of bevacizumab, irinotecan and erlotinib in children with progressive diffuse intrinsic pontine glioma. J Neurooncol 153:263–271
Article CAS PubMed Google Scholar
Gallego Perez-Larraya J, Garcia-Moure M, Labiano S et al (2022) Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma. N Engl J Med 386:2471–2481
Yamasaki F, Nishibuchi I, Karakawa S et al (2021) T2-FLAIR Mismatch Sign and Response to Radiotherapy in Diffuse Intrinsic Pontine Glioma. Pediatr Neurosurg 56:1–9
Janssens GO, Gandola L, Bolle S et al (2017) Survival benefit for patients with diffuse intrinsic pontine glioma (DIPG) undergoing re-irradiation at first progression: A matched-cohort analysis on behalf of the SIOP-E-HGG/DIPG working group. Eur J Cancer 73:38–47
Werbrouck C, Evangelista CCS, Lobon-Iglesias MJ et al (2019) TP53 Pathway Alterations Drive Radioresistance in Diffuse Intrinsic Pontine Gliomas (DIPG). Clin Cancer Res 25:6788–6800
Article CAS PubMed Google Scholar
Harward S, Harrison Farber S, Malinzak M, Becher O, Thompson EM (2018) T2-weighted images are superior to other MR image types for the determination of diffuse intrinsic pontine glioma intratumoral heterogeneity. Childs Nerv Syst 34:449–455
Cooney TM, Cohen KJ, Guimaraes CV et al (2020) Response assessment in diffuse intrinsic pontine glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group. Lancet Oncol 21:e330–e336
Makepeace L, Scoggins M, Mitrea B et al (2020) MRI Patterns of Extrapontine Lesion Extension in Diffuse Intrinsic Pontine Gliomas. AJNR Am J Neuroradiol 41:323–330
Article CAS PubMed PubMed Central Google Scholar
Lasocki A, Gaillard F, Gorelik A, Gonzales M (2018) MRI Features Can Predict 1p/19q Status in Intracranial Gliomas. AJNR Am J Neuroradiol 39:687–692
Article CAS PubMed PubMed Central Google Scholar
Carceller F, Fowkes LA, Khabra K et al (2016) Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma. J Neurooncol 129:109–121
Chassot A, Canale S, Varlet P et al (2012) Radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma. J Neurooncol 106:399–407
Article CAS PubMed Google Scholar
Vajapeyam S, Brown D, Billups C et al (2020) Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium. AJNR Am J Neuroradiol 41:718–724
Article CAS PubMed PubMed Central Google Scholar
Mackay A, Burford A, Carvalho D et al (2017) Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. Cancer Cell 32:520–537.e525
Article CAS PubMed PubMed Central Google Scholar
Qazi MA, Vora P, Venugopal C et al (2017) Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma. Ann Oncol 28:1448–1456
Article CAS PubMed Google Scholar
Binder H, Willscher E, Loeffler-Wirth H et al (2019) DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development. Acta Neuropathol Commun 7:59
Article CAS PubMed PubMed Central Google Scholar
Lobel U, Sedlacik J, Reddick WE et al (2011) Quantitative diffusion-weighted and dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging analysis of T2 hypointense lesion components in pediatric diffuse intrinsic pontine glioma. AJNR Am J Neuroradiol 32:315–322
Article CAS PubMed PubMed Central Google Scholar
Conway AE, Reddick WE, Li Y et al (2014) Occult” post-contrast signal enhancement in pediatric diffuse intrinsic pontine glioma is the MRI marker of angiogenesis? Neuroradiology 56:405–412
Article PubMed PubMed Central Google Scholar
Clerk-Lamalice O, Reddick WE, Li X et al (2016) MRI Evaluation of Non-Necrotic T2-Hyperintense Foci in Pediatric Diffuse Intrinsic Pontine Glioma. AJNR Am J Neuroradiol 37:1930–1937
Comments (0)