Association of triglyceride-glucose index and its related parameters with atherosclerotic cardiovascular disease: evidence from a 15-year follow-up of Kailuan cohort

GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of disease study 2019. Lancet. 2020;396(10258):1204–22.

Article  Google Scholar 

Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, Barengo NC, Beaton AZ, Benjamin EJ, Benziger CP, et al. Global burden of cardiovascular diseases and risk factors, 1990–2019: update from the GBD 2019 study. J Am Coll Cardiol. 2020;76(25):2982–3021.

Article  PubMed  PubMed Central  Google Scholar 

Wang W, Hu M, Liu H, Zhang X, Li H, Zhou F, Liu YM, Lei F, Qin JJ, Zhao YC, et al. Global burden of disease study 2019 suggests that metabolic risk factors are the leading drivers of the burden of ischemic heart disease. Cell Metab. 2021;33(10):1943–56 e1942.

Article  CAS  PubMed  Google Scholar 

Adeva-Andany MM, Martínez-Rodríguez J, González-Lucán M, Fernández-Fernández C, Castro-Quintela E. Insulin resistance is a cardiovascular risk factor in humans. Diabetes Metab Syndr. 2019;13(2):1449–55.

Article  PubMed  Google Scholar 

Muniyappa R, Lee S, Chen H, Quon MJ. Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab. 2008;294(1):E15–26.

Article  CAS  PubMed  Google Scholar 

Toro-Huamanchumo CJ, Urrunaga-Pastor D, Guarnizo-Poma M, Lazaro-Alcantara H, Paico-Palacios S, Pantoja-Torres B, Ranilla-Seguin VDC, Benites-Zapata VA. Triglycerides and glucose index as an insulin resistance marker in a sample of healthy adults. Diabetes Metab Syndr. 2019;13(1):272–7.

Article  PubMed  Google Scholar 

Wang A, Wang G, Liu Q, Zuo Y, Chen S, Tao B, Tian X, Wang P, Meng X, Wu S, et al. Triglyceride-glucose index and the risk of stroke and its subtypes in the general population: an 11-year follow-up. Cardiovasc Diabetol. 2021;20(1):46.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tian X, Zuo Y, Chen S, Liu Q, Tao B, Wu S, Wang A. Triglyceride-glucose index is associated with the risk of myocardial infarction: an 11-year prospective study in the Kailuan cohort. Cardiovasc Diabetol. 2021;20(1):19.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miao H, Zhou Z, Yang S, Zhang Y. The association of triglyceride-glucose index and related parameters with hypertension and cardiovascular risk: a cross-sectional study. Hypertens Res. 2023;47(4):877–86.

Article  PubMed  Google Scholar 

Schmiegelow MD, Hedlin H, Stefanick ML, Mackey RH, Allison M, Martin LW, Robinson JG, Hlatky MA. Insulin resistance and risk of cardiovascular disease in postmenopausal women: a cohort study from the women’s health initiative. Circ Cardiovasc Qual Outcomes. 2015;8(3):309–16.

Article  PubMed  Google Scholar 

Reho JJ, Rahmouni K. Oxidative and inflammatory signals in obesity-associated vascular abnormalities. Clin Sci. 2017;131(14):1689–700.

Article  CAS  Google Scholar 

Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature. 2006;444(7121):875–80.

Article  PubMed  Google Scholar 

Zhang X, Zhang T, He S, Jia S, Zhang Z, Ye R, Yang X, Chen X. Association of metabolic syndrome with TyG index and TyG-related parameters in an urban Chinese population: a 15-year prospective study. Diabetol Metab Syndr. 2022;14(1):84.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xue Y, Xu J, Li M, Gao Y. Potential screening indicators for early diagnosis of NAFLD/MAFLD and liver fibrosis: triglyceride glucose index-related parameters. Front Endocrinol (Lausanne). 2022;13:951689.

Article  PubMed  Google Scholar 

Cheng W, Kong F, Chen S. Comparison of the predictive value of four insulin resistance surrogates for the prevalence of hypertension: a population-based study. Diabetol Metab Syndr. 2022;14(1):137.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang X, Liu J, Cheng Z, Zhong Y, Chen X, Song W. Triglyceride glucose-body mass index and the risk of diabetes: a general population-based cohort study. Lipids Health Dis. 2021;20(1):99.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhao Y, Zhang J, Chen C, Qin P, Zhang M, Shi X, Yang Y, Lu J, Sun L, Hu D. Comparison of six surrogate insulin resistance indexes for predicting the risk of incident stroke: the rural Chinese cohort study. Diabetes Metab Res Rev. 2022;38(7):e3567.

Article  CAS  PubMed  Google Scholar 

Huang YC, Huang JC, Lin CI, Chien HH, Lin YY, Wang CL, Liang FW, Dai CY, Chuang HY. Comparison of Innovative and Traditional Cardiometabolic Indices in Estimating Atherosclerotic Cardiovascular Disease Risk in Adults. Diagnostics. 2021;11(4):603.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dang K, Wang X, Hu J, Zhang Y, Cheng L, Qi X, Liu L, Ming Z, Tao X, Li Y. The association between triglyceride-glucose index and its combination with obesity indicators and cardiovascular disease: NHANES 2003–2018. Cardiovasc Diabetol. 2024;23(1):8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu Z, Deng B, Huang Q, Tu R, Yu F, Xia J, Feng J. Comparison of seven surrogate insulin resistance indexes for predicting the prevalence of carotid atherosclerosis in normal-weight individuals. Front Public Health. 2023;11:1241523.

Article  PubMed  PubMed Central  Google Scholar 

Wu S, An S, Li W, Lichtenstein AH, Gao J, Kris-Etherton PM, Wu Y, Jin C, Huang S, Hu FB, et al. Association of trajectory of cardiovascular health score and incident cardiovascular disease. JAMA Netw Open. 2019;2(5):e194758.

Article  PubMed  PubMed Central  Google Scholar 

Wang C, Yuan Y, Zheng M, Pan A, Wang M, Zhao M, Li Y, Yao S, Chen S, Wu S, et al. Association of age of onset of hypertension with cardiovascular diseases and mortality. J Am Coll Cardiol. 2020;75(23):2921–30.

Article  PubMed  Google Scholar 

Zhou YF, Chen S, Wang G, Chen S, Zhang YB, Chen JX, Tu ZZ, Liu G, Wu S, Pan A. Effectiveness of a workplace-based, multicomponent hypertension management program in real-world practice: a propensity-matched analysis. Hypertension. 2022;79(1):230–40.

Article  CAS  PubMed  Google Scholar 

Li Y, Wu S, Gao J, Zhang Y, Zuo Y, Tian X, Chen S, Xing A, Wang A, He Y. Association of stroke with metabolic dysfunction-associated fatty liver disease with and without CKD. Am J Kidney Dis. 2024;83(4):477–88.

Article  CAS  PubMed  Google Scholar 

Wang YH, Wang J, Chen SH, Li JQ, Lu QD, Vitiello MV, Wang F, Tang XD, Shi J, Lu L, et al. Association of longitudinal patterns of habitual sleep duration with risk of cardiovascular events and all-cause mortality. JAMA Netw Open. 2020;3(5):e205246.

Article  PubMed  PubMed Central  Google Scholar 

Tunstall-Pedoe H, Kuulasmaa K, Amouyel P, Arveiler D, Rajakangas AM, Pajak A. Myocardial infarction and coronary deaths in the World Health Organization MONICA Project: registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents. Circulation. 1994;90(1):583–612.

Article  CAS  PubMed  Google Scholar 

Special Report from the World Health Organization. Stroke-1989: Recommendations on stroke prevention, diagnosis, and therapy---report of the WHO task force on stroke and other cerebrovascular disorders. Stroke. 1989;20(10):1407–31.

Article  Google Scholar 

PM G, TM T. Proportional hazards tests and diagnostics based on weighted residuals. Biometrika. 1994;81:515–26.

Article  Google Scholar 

Li F, Wang Y, Shi B, Sun S, Wang S, Pang S, Wu X. Association between the cumulative average triglyceride glucose-body mass index and cardiovascular disease incidence among the middle-aged and older population: a prospective nationwide cohort study in China. Cardiovasc Diabetol. 2024;23(1):16.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xu W, Zhao H, Han X, Liu J, Li H, Sun J, Xing A, Chen S, Wu S, Wu Y. Relationship between early-onset stroke and triglyceride-glucose index among young Chinese adults. Lipids Health Dis. 2023;22(1):3.

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