Vilgrain, V., Van Beers, B. E. & Pastor, C. M. Insights into the diagnosis of hepatocellular carcinomas with hepatobiliary MRI. J. Hepatol. 64, 708–716 (2016).
Narita, M. et al. Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinoma. J. Gastroenterol. 44, 793–798 (2009).
Article CAS PubMed Google Scholar
Sourbron, S. A tracer-kinetic field theory for medical imaging. IEEE Trans. Med. Imaging 33, 935–946 (2014).
Pastor, C. M. & Brouwer, K. L. R. New pharmacokinetic parameters of imaging substrates quantified from rat liver compartments. Drug Metab. Dispos. 50, 58–64 (2022).
Article CAS PubMed Google Scholar
Pastor, C. M. & Vilgrain, V. Steatosis alters the activity of hepatocyte membrane transporters in obese rats. Cells 10, 2733 (2021).
Article CAS PubMed PubMed Central Google Scholar
Taniguchi, T. et al. Interindividual diversity in expression of organic anion uptake transporters in normal and cirrhotic human liver. Hepatol. Commun. 4, 739–752 (2020).
Article CAS PubMed PubMed Central Google Scholar
Vildhede, A., Kimoto, E., Pelis, R. M., Rodrigues, A. D. & Varma, M. V. S. Quantitative proteomics and mechanistic modeling of transporter-mediated disposition in nonalcoholic fatty liver disease. Clin. Pharmacol. Ther. 107, 1128–1137 (2020).
Article CAS PubMed Google Scholar
Hardwick, R. N., Fisher, C. D., Canet, M. J., Scheffer, G. L. & Cherrington, N. J. Variations in ATP-binding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease. Drug Metab. Dispos. 39, 2395–2402 (2011).
Article CAS PubMed PubMed Central Google Scholar
Leporq, B. et al. Quantification of hepatic perfusion and hepatocyte function with dynamic gadoxetic acid-enhanced MRI in patients with chronic liver disease. Clin. Sci. 132, 813–824 (2018).
Bastati, N. et al. Noninvasive differentiation of simple steatosis and steatohepatitis by using gadoxetic acid-enhanced MR imaging in patients with nonalcoholic fatty liver disease: a proof-of-concept study. Radiology 271, 739–747 (2014).
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