Our sincere thanks to the Dr Anand Srinivasan, Additional Professor, Department of Pharmacology, AIIMS Bhubaneswar for his valuable suggestions on the study design. We also like to thank the technical staffs of the Biochemistry Hospital Laboratory, Department of Biochemistry, AIIMS Bhubaneswar for their cooperation and support in the study. We are grateful to Mr.Balabhadra Kar for consenting and volunteering to donate urine sample for this study.