Raman R, Sasisekharan V, Sasisekharan R. Structural insights into biological roles of protein-glycosaminoglycan interactions. Chem Biol. 2005;12(3):267–77.

Article  CAS  PubMed  Google Scholar 

Farndale RW, Buttle DJ, Barrett AJ. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta. 1986;883(2):173–7.

Article  CAS  PubMed  Google Scholar 

Templeton DM. The basis and applicability of the dimethylmethylene blue binding assay for sulfated glycosaminoglycans. Connect Tissue Res. 1988;17(1):23–32.

Article  CAS  PubMed  Google Scholar 

Stone JE, Akhtar N, Botchway S, Pennock CA. Interaction of 1,9-dimethylmethylene blue with glycosaminoglycans. Ann Clin Biochem. 1994;31(Pt 2):147–52.

Article  CAS  PubMed  Google Scholar 

de Jong JG, Wevers RA, Laarakkers C, Poorthuis BJ. Dimethylmethylene blue-based spectrophotometry of glycosaminoglycans in untreated urine: a rapid screening procedure for mucopolysaccharidoses. Clin Chem. 1989;35(7):1472–7.

Article  PubMed  Google Scholar 

de Jong JG, Wevers RA, Liebrand-van Sambeek R. Measuring urinary glycosaminoglycans in the presence of protein: an improved screening procedure for mucopolysaccharidoses based on dimethylmethylene blue. Clin Chem. 1992;38(6):803–7.

Article  PubMed  Google Scholar 

Indika N-LR, Jasinge E, Wijetunge S, Peiris H, Engelen MP, Deutz NE et al. Comparison of urine glycosaminoglycan excretion between children with autism spectrum disorder and typically developed children. 2023.

Han X, Sanderson P, Nesheiwat S, Lin L, Yu Y, Zhang F, et al. Structural analysis of urinary glycosaminoglycans from healthy human subjects. Glycobiology. 2020;30(3):143–51.

Article  CAS  PubMed  Google Scholar 

Mason KE, Meikle PJ, Hopwood JJ, Fuller M. Characterization of sulfated oligosaccharides in mucopolysaccharidosis type IIIA by electrospray ionization mass spectrometry. Anal Chem. 2006;78(13):4534–42.

Article  CAS  PubMed  Google Scholar 

Zheng CH, Levenston ME. Fact versus artifact: avoiding erroneous estimates of sulfated glycosaminoglycan content using the dimethylmethylene blue colorimetric assay for tissue-engineered constructs. Eur Cell Mater. 2015;29:224–36 (discussion 36).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Andrade F, Prieto JA, Elorz J, Martin S, Sanjurjo P, Aldamiz-Echevarria L. Stability of urinary glycosaminoglycans in patients with mucopolysaccharidoses. Clin Chim Acta. 2008;388(1–2):73–7.

Article  CAS  PubMed  Google Scholar 

Gray G, Claridge P, Jenkinson L, Green A. Quantitation of urinary glycosaminoglycans using dimethylene blue as a screening technique for the diagnosis of mucopolysaccharidoses-an evaluation. Ann Clin Biochem. 2007;44(4):360–3.

Article  CAS  PubMed  Google Scholar 

Dave M, Chawla P, Dherai A, Ashavaid T. Urinary glycosaminoglycan estimation as a routine clinical service. Indian J Clin Biochem. 2015;30(3):293–7.

Article  CAS  PubMed  Google Scholar 

Pandey SK, Polipalli SK, Kapoor S. Dimethylmethylene blue: a tool for MPS screening. Int J Bioassays. 2015;4:4269–71.

CAS  Google Scholar 

Whitley CB, Draper KA, Dutton CM, Brown PA, Severson SL, France LA. Diagnostic test for mucopolysaccharidosis. II. Rapid quantification of glycosaminoglycan in urine samples collected on a paper matrix. Clin Chem. 1989;35(10):2074–81.

Article  CAS  PubMed  Google Scholar 

Mitra A, Nath RK, Biswas S, Chakraborty AK, Panda AK. A comparative study on the physico-chemical properties of bacterial capsular polysaccharides from different serotypes of Klebsiella. J Photochem Photobiol A Chem. 2006;178(1):98–105.

Article  CAS  Google Scholar 

Volpi N. Analytical aspects of pharmaceutical grade chondroitin sulfates. J Pharm Sci. 2007;96(12):3168–80.

Article  CAS  PubMed  Google Scholar 

Coulson-Thomas VJ, Gesteira TFJB. Dimethylmethylene blue assay (DMMB). Bio Protoc. 2014;4(18):e1236.

Article  Google Scholar 

Mehta D, Purushothama S, Stevenson L. Parallelism: the foundation of biomarker assay development and validation. Bioanalysis. 2018;10(12):897–9.

Article  CAS  PubMed  Google Scholar 

de Lima CR, Baccarin RY, Michelacci YM. Reliability of 1,9-dimethylmethylene blue tests in comparison to agarose gel electrophoresis for quantification of urinary glycosaminoglycans. Clin Chim Acta. 2007;378(1–2):206–15.

Article  PubMed  Google Scholar 

Miller WG, Tate JR, Barth JH, Jones GR. Harmonization: the sample, the measurement, and the report. Ann Lab Med. 2014;34(3):187–97.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schlotawa L, Adang LA, Radhakrishnan K, Ahrens-Nicklas RC. Multiple sulfatase deficiency: a disease comprising mucopolysaccharidosis, sphingolipidosis, and more caused by a defect in posttranslational modification. Int J Mol Sci. 2020;21(10):3448.

Article  CAS  PubMed  PubMed Central  Google Scholar