Allegretta, G., Weidel, E., Empting, M., & Hartmann, R. W. (2015). Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD. European Journal of Medicinal Chemistry,90, 351–359.

Article  CAS  PubMed  Google Scholar 

Amole, K. L., Bello, I. A., & Oyewale, A. O. (2019). Synthesis, characterization and antibacterial activities of new fluorinated chalcones. Chemistry Africa,2, 47–55.

Article  CAS  Google Scholar 

Bajpai, V. K., Sharma, A., & Baek, K. H. (2013). Antibacterial mode of action of Cudrania tricuspidata fruit essential oil, affecting membrane permeability and surface characteristics of food-borne pathogens. Food Control,32, 582–590.

Article  CAS  Google Scholar 

Boopathi, S., Gopinath, S., Boopathi, T., Balamurugan, V., Rajeshkumar, R., & Sundararaman, M. (2012). Characterization and antimicrobial properties of silver and silver oxide nanoparticles synthesized by cell-free extract of a mangrove-associated Pseudomonas aeruginosa M6 using two different thermal treatments. Industrial & Engineering Chemistry Research,51, 5976–5985.

Article  CAS  Google Scholar 

Boopathi, S., Selvakumar, G., & Sivakumar, N. (2017a). Quorum quenching potentials of probiotic Enterococcus durans LAB38 against methicillin resistant Staphylococcus aureus. Asian Journal of Pharmaceutical and Clinical Research,10, 445–450.

Article  CAS  Google Scholar 

Boopathi, S., Vashisth, R., Manoharan, P., Kandasamy, R., & Sivakumar, N. (2017b). Stigmatellin Y–An anti-biofilm compound from Bacillus subtilis BR4 possibly interferes in PQS–PqsR mediated quorum sensing system in Pseudomonas aeruginosa. Bioorganic & Medicinal Chemistry Letters,27, 2113–2118.

Article  CAS  Google Scholar 

Boopathi, S., Vashisth, R., Mohanty, A. K., Jia, A. Q., Sivakumar, N., Alharbi, N. S., Khaled, J. M., Juliet, A., & Arockiaraj, J. (2022). Investigation of interspecies crosstalk between probiotic Bacillus subtilis BR4 and Pseudomonas aeruginosa using metabolomics analysis. Microbial Pathogenesis,166, 105542.

Article  CAS  PubMed  Google Scholar 

Bradford, N. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry,72, 248–254.

Article  CAS  PubMed  Google Scholar 

Cao, Y., Liu, Y., Mao, W., Chen, R., He, S., Gao, X., Zhou, Z., & Yao, B. (2014). Effect of dietary N-acyl homoserin lactonase on the immune response and the gut microbiota of zebrafish, Danio rerio, infected with Aeromonas hydrophila. Journal of the World Aquaculture Society,45, 149–162.

Article  CAS  Google Scholar 

Chatterjee, M., D’Morris, S., Paul, V., Warrier, S., Vasudevan, A. K., Vanuopadath, M., Nair, S. S., Paul-Prasanth, B., Mohan, C. G., & Biswas, R. (2017). Mechanistic understanding of Phenyllactic acid mediated inhibition of quorum sensing and biofilm development in Pseudomonas aeruginosa. Applied Microbiology and Biotechnology,101, 8223–8236.

Article  CAS  PubMed  Google Scholar 

Cheepurupalli, L., Raman, T., Rathore, S. S., & Ramakrishnan, J. (2017). Bioactive molecule from Streptomyces sp. mitigates MDR Klebsiella pneumoniae in zebrafish infection model. Frontiers in Microbiology,8, 614.

Article  PubMed  PubMed Central  Google Scholar 

Cornet, C., Dyballa, S., Terriente, J., & Di Giacomo, V. (2019). ZeOncoTest: Refining and automating the zebrafish xenograft model for drug discovery in cancer. Pharmaceuticals,13, 1.

Article  PubMed  PubMed Central  Google Scholar 

Costa, G. M., Endo, E. H., Cortez, D. A., Nakamura, T. U., Nakamura, C. V., & Dias Filho, B. P. (2016). Antimicrobial effects of Piper hispidum extract, fractions and chalcones against Candida albicans and Staphylococcus aureus. Journal De Mycologie Medicale,26, 217–226.

Article  CAS  PubMed  Google Scholar 

Dhivya, L. S., Pradeepa, B. R., & Sarvesh, S. (2022). Synthesis and in vitro studies for structure-based design of novel chalcones as antitubercular agents targeting InhA. Future Medicinal Chemistry,14, 851–866.

Article  CAS  PubMed  Google Scholar 

Di Mascio, P., Martinez, G. R., Miyamoto, S., Ronsein, G. E., Medeiros, M. H. G., & Cadet, J. (2019). Singlet Molecular oxygen reactions with nucleic acids, lipids, and proteins. Chemical Reviews,119, 2043–2086.

Article  PubMed  Google Scholar 

Dos Santos, A. T. L., de Araújo-Neto, J. B., Costa da Silva, M. M., Paulino da Silva, M. E., Carneiro, J. N. P., Fonseca, V. J. A., Coutinho, H. D. M., Bandeira, P. N., Santos, D., da Silva Mendes, H. S., et al. (2023). Synthesis of chalcones and their antimicrobial and drug potentiating activities. Microbial Pathogenesis,180, 106129.

Article  CAS  PubMed  Google Scholar 

Ferreira, C., Pereira, A. M., Pereira, M. C., Melo, L. F., & Simões, M. (2011). Physiological changes induced by the quaternary ammonium compound benzyldimethyldodecylammonium chloride on Pseudomonas fluorescens. The Journal of Antimicrobial Chemotherapy,66, 1036–1043.

Article  CAS  PubMed  Google Scholar 

Geng, Y. F., Yang, C., Zhang, Y., Tao, S. N., Mei, J., Zhang, X. C., Sun, Y. J., & Zhao, B. T. (2021). An innovative role for luteolin as a natural quorum sensing inhibitor in Pseudomonas aeruginosa. Life Sciences,274, 119325.

Article  CAS  PubMed  Google Scholar 

Ghribia, L., Ghouilaa, H., Omrib, A., Besbesb, M., & Janneta, H. B. (2014). Antioxidant and anti–acetylcholinesterase activities of extracts and secondary metabolites from Acacia cyanophylla. Asian Pacific Journal of Tropical Biomedicine,4, S417–S423.

Article  PubMed  PubMed Central  Google Scholar 

Guru, A., & Arockiaraj, J. (2023). Exposure to environmental pollutant bisphenol a causes oxidative damage and lipid accumulation in zebrafish larvae: Protective role of WL15 peptide derived from cysteine and glycine-rich protein 2. Journal of Biochemical and Molecular Toxicology,37, e23223.

Article  CAS  PubMed  Google Scholar 

Haridevamuthu, B., Manjunathan, T., Guru, A., Kumar, R. S., Rajagopal, R., Kuppusamy, P., Juliet, A., Gopinath, P., & Arockiaraj, J. (2022a). Hydroxyl containing benzo[b]thiophene analogs mitigates the acrylamide induced oxidative stress in the zebrafish larvae by stabilizing the glutathione redox cycle. Life Sciencees,298, 120507.

Article  CAS  Google Scholar 

Haridevamuthu, B., Manjunathan, T., Guru, A., Ranjith Wilson Alphonse, C., Boopathi, S., Murugan, R., Gatasheh, M. K., Hatamleh, A., Juliet, A., Gopinath, A., et al. (2022b). Amelioration of acrylamide induced neurotoxicity by benzo[b]thiophene analogs via glutathione redox dynamics in zebrafish larvae. Brain Research,1788, 147941.

Article  CAS  PubMed  Google Scholar 

Haridevamuthu, B., Seenivasan, B., Priya, P. S., Muthuraman, S., Kumar, R. S., Manikandan, K., Almutairi, B. O., Almutairi, M. H., Arokiyaraj, S., Gopinath, P., et al. (2023). Hepatoprotective effect of dihydroxy piperlongumine in high cholesterol-induced non-alcoholic fatty liver disease zebrafish via antioxidant activity. European Journal of Pharmacology,945, 175605.

Article  CAS  PubMed  Google Scholar 

Hason, M., & Bartůněk, P. (2019). Zebrafish models of cancer-new insights on modeling human cancer in a non-mammalian vertebrate. Genes,10, 935.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jakubczyk, K., Drużga, A., Katarzyna, J., & Skonieczna-Żydecka, K. (2020). Antioxidant potential of curcumin—a meta-analysis of randomized clinical trials. Antioxidants,9, 1092.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jasim, H. A., Nahar, L., Jasim, M. A., Moore, S. A., Ritchie, K. J., & Sarker, S. D. (2021). Chalcones: Synthetic chemistry follows where nature leads. Biomolecules,11, 1203.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Konai, M. M., & Haldar, J. (2015). Lysine-based small molecules that disrupt biofilms and kill both actively growing planktonic and nondividing stationary phase bacteria. ACS Infectious Diseases,1, 469–478.

Article  CAS  PubMed  Google Scholar 

Leal, A. L. A. B., da Silva, P. T., da Rocha, M. N., Marinho, E. M., Marinho, E. S., Marinho, M. M., Bandeira, P. N., Nogueira, S., Barreto, C. E., Teixeira, H. M. R., et al. (2021). Potentiating activity of Norfloxacin by synthetic chalcones against NorA overproducing Staphylococcus aureus. Microbial Pathogenesis,155, 104894.

Article  Google Scholar 

Lee, S. B., Choe, Y., Chon, T. S., & Kang, H. Y. (2015). Analysis of zebrafish (Danio rerio) behavior in response to bacterial infection using a self-organizing map. BMC Veterinary Research,11, 269.

Article  PubMed  PubMed Central  Google Scholar 

Lee, S. H., Ko, C. I., Jee, Y., Jeong, Y., Kim, M., Kim, J. S., & Jeon, Y. J. (2013). Anti-inflammatory effect of fucoidan extracted from Ecklonia cava in zebrafish model. Carbohydrate Polymers,92, 84–89.

Article  CAS  PubMed  Google Scholar 

Lite, C., Guru, A., Juliet, M., & Arockiaraj, J. (2022). Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety-like neurobehavioral response associated with oxidative stress and apoptosis in the head of zebrafish larvae. Environmental Toxicology,37, 1988–2004.

Article  CAS  PubMed  ADS  Google Scholar 

Lushchak, V. I. (2016). Contaminant-induced oxidative stress in fish: A mechanistic approach. Fish Physiology and Biochemistry,42, 711–747.

Article  CAS  PubMed  Google Scholar 

Maharajan, K., Muthulakshmi, S., Nataraj, B., Ramesh, M., & Kadirvelu, K. (2018). Toxicity assessment of pyriproxyfen in vertebrate model zebrafish embryos (Danio rerio): A multi biomarker study. Aquatic Toxicology,196, 132–145.

Article  CAS  PubMed  Google Scholar 

Molagoda, I. M. N., Jayasingha, J. A. C. C., Choi, Y. H., Jayasooriya, R. G. P. T., Kang, C. H., & Kim, G. Y. (2021). Fisetin inhibits lipopolysaccharide-induced inflammatory response by activating β-catenin, leading to a decrease in endotoxic shock. Scientific Reports,11, 8377.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Moradali, M. F., Ghods, S., &