Cystatin C-derived estimated glomerular filtration rate in children with sickle cell anaemia

Chakravorty S, Williams TN. Sickle cell Disease: a neglected chronic Disease of increasing global health importance. Arch Dis Child. 2015;100:48–53.

Article  PubMed  Google Scholar 

Kato GJ, Piel FB, Reid CD, Gaston MH, Ohene-Frempong K, Krishnamurti L, et al. Sickle cell Disease. Nat Rev Dis Prim. 2018;4:1–24.

Google Scholar 

Piel FB, Patil AP, Howes RE, Nyangiri OA, Gething PW, Williams TN, et al. Global distribution of the sickle cell gene and geographical confirmation of the Malaria hypothesis. Nat Commun. 2010;1. https://doi.org/10.1038/ncomms1104.

Piel FB, Hay SI, Gupta S, Weatherall DJ, Williams TN. Global burden of sickle cell anaemia in children under five, 2010–2050: modelling based on demographics, excess mortality, and interventions. PLoS Med. 2013;10:e1001484.

Article  PubMed  PubMed Central  Google Scholar 

Weatherall DJ. The inherited Diseases of hemoglobin are an emerging global health burden. Blood. 2010;115:4331–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Federal Ministry of Health Nigeria. National Guideline for the Contol and Management of Sickle Cell Disease. Fed Ministry Health Nigeria: Abuja. 2014. https://doi.org/10.1039/c7dt00953d. 1st ed.

Article  Google Scholar 

Nath KA, Hebbel RP. Sickle cell Disease: renal manifestations and mechanisms. Nat Rev Nephrol. 2015;11:161–71.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Knight EL, Verhave JC, Spiegelman D, Hillege HL, De Zeeuw D, Curhan GC, et al. Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement. Kidney Int. 2004;65:1416–21.

Article  CAS  PubMed  Google Scholar 

Langlois V. Laboratory evaluation at different ages. Comprehensive Pediatric Nephrology. Elsevier Inc.; 2008. pp. 39–54.

Sundaram N, Bennett M, Wilhelm J, Kim M-O, Atweh G, Devarajan P, et al. Biomarkers for early detection of sickle Nephropathy. Am J Hematol. 2011;86:559–66.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ibitoye P, Jiya N, Airede K, Ugege M, Jiya F, Isezuo K. Glomerular filtration rate in steady state children with sickle cell anaemia in Sokoto, North-Western Nigeria. Afr J Paediatr Nephrol. 2016;3:21–5.

Google Scholar 

Flynn JT, Falkner BE. New clinical practice guideline for the management of High Blood Pressure in children and adolescents. Hypertension. 2017;70:683–6.

Article  CAS  PubMed  Google Scholar 

WHO. BMI-for-age. WHO Growth Ref 2007;1–7.

Oyedeji G. Socio-economic and cultural background of hospitalized children in Ilesha. Niger J Paediatr. 1985;12(4):111–7.

Google Scholar 

Filler G, Lepage N. Should the Schwartz formula for estimation of GFR be replaced by cystatin C formula? Pediatr Nephrol. 2003;18:981–5.

Article  PubMed  Google Scholar 

CKD Work Group. Kidney Disease: improving Global Outcome (KDIGO) Clinical Practice Guideline for the evaluation and management of chronic Kidney Disease. Kidney Int Suppl. 2013;3:1–150.

Google Scholar 

Farouk AG, Elechi AH, Yauba MS, Mustapha MG, Ibrahim BA, Ibrahim HA, et al. Assessment of renal function in children with sickle cell anaemia in University of Maiduguri Teaching Hospital. Afr J Paediatr Nephrol. 2017;4:1–9.

Google Scholar 

Alvarez O, Zilleruelo G, Wright D, Montane B, Lopez-Mitnik G. Serum cystatin C levels in children with sickle cell Disease. Pediatr Nephrol. 2006;21:533–7.

Article  PubMed  Google Scholar 

Ware RE, Rees RC, Sarnaik SA, Iyer RV, Alvarez OA, Casella JF, et al. Renal function in infants with sickle cell anemia: baseline data from the BABY HUG trial. J Pediatr. 2010;156:66–70.

Article  PubMed  PubMed Central  Google Scholar 

Da Silva Junior GB, Libório AB, De Francesco Daher E. New insights on pathophysiology, clinical manifestations, diagnosis, and treatment of sickle cell Nephropathy. Ann Hematol. 2011;90:1371–9.

Article  Google Scholar 

Afangbedji N, Jerebtsova M. Glomerular filtration rate abnormalities in sickle cell Disease. Front Med. 2022;9:1029224.

Article  Google Scholar 

Olowu W, Taiwo O, Oyelami A, Durosinmi M, Adeodu O, Akinsola A, et al. Glomerular filtration rate in Nigerian children with homozygous sickle cell Disease. Niger J Med. 2002;11:23–5.

CAS  PubMed  Google Scholar 

Unal S, Kotan C, Delibas A, Oztas Y, Cystatin C. Beta2 microglobulin, N-acetyl-beta-D-glucosaminidase, retinol-binding protein, and endothelin 1 levels in the evaluation of sickle cell Disease Nephropathy. Pediatr Hematol Oncol. 2015;32:250–7.

Article  CAS  PubMed  Google Scholar 

Shahriari M, Fallahzadeh M-H, Malekmakan L, Mojtahedi S-Y. Renal Complications of sickle cell syndrome in southern Iran. Iran J Pediatr. 2017;27:e11016.

Article  Google Scholar 

Aygun B, Mortier NA, Smeltzer MP, Hankins JS, Ware RE. Glomerular hyperfiltration and albuminuria in children with sickle cell anemia. Pediatr Nephrol. 2011;26:1285–90.

Article  PubMed  PubMed Central  Google Scholar 

Lebensburger JD, Aban I, Pernell B, Kasztan M, Feig DI, Hilliard LM, et al. Hyperfiltration during early childhood precedes albuminuria in pediatric sickle cell Nephropathy. Am J Hematol. 2019;94:417–23.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alvarez O, Zilleruelo G, Wright D, Montane B, Lopez-Mitnik G, Saraf SL, et al. The pattern of blood pressure and renal function among children with sickle cell anaemia presenting in a tertiary health institution in Nigeria. Pediatr Nephrol. 2003;14:083–92.

Google Scholar 

Mcpherson Yee M, Jabbar SF, Osunkwo I, Clement L, Lane PA, Eckman JR, et al. Chronic Kidney Disease and albuminuria in children with sickle cell Disease. Clin J Am Soc Nephrol. 2011;6:2628–33.

Article  PubMed  PubMed Central  Google Scholar 

Ephraim RKD, Osakunor DNM, Cudjoe O, Oduro EA, Asante-Asamani L, Mitchell J, et al. Chronic Kidney Disease is common in sickle cell Disease: a cross-sectional study in the Tema Metropolis, Ghana. BMC Nephrol. 2015;16:10–2.

Article  Google Scholar 

Schwartz GJ, Furth S, Cole SR, Warady B, Mũoz A. Glomerular filtration rate via plasma iohexol disappearance: pilot study for chronic Kidney Disease in children. Kidney Int. 2006;69:2070–7.

Article  CAS  PubMed  Google Scholar 

Schmitt F, Martinez F, Brillet G, Giatras I, Choukroun G, Girot R, et al. Early glomerular dysfunction in patients with sickle cell anemia. Am J Kidney Dis. 1998;32:208–14.

Article  CAS  PubMed  Google Scholar 

Ekure EN, Onifade E, Esezobor CI, Banwo T. Systolic blood pressure of Nigerian children with sickle cell Disease. Niger J Paediatr. 2012;39:105–9.

Google Scholar 

Hatch FE, Crowe LR, Miles DE, Young JP, Portner ME. Altered vascular reactivity in Sickle Hemoglobinopathy: a possible protective factor from Hypertension. Am J Hypertens. 1989;2:2–8.

Article  CAS  PubMed  Google Scholar 

Usmani A, Machado RF. Vascular Complications of sickle cell Disease. Clin Hemorheol Microcirc. 2018;68:205–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Johnson CS, Giorgio AJ. Arterial blood pressure in adults with sickle cell Disease. Arch Intern Med. 1981;141:891–3.

Article  CAS  PubMed  Google Scholar 

Bodas P, Huang A, O’Riordan MA, Sedor JR, Dell KM. The prevalence of Hypertension and abnormal kidney function in children with sickle cell disease- a cross sectional review. BMC Nephrol. 2013;14:237–42.

Article  PubMed  PubMed Central  Google Scholar 

Inusa BPD, Mariachiara L, Giovanni P, Ataga KI. Sickle cell Nephropathy: current understanding of the presentation, diagnostic and therapeutic challenges. In: Guenova M, Balatzenko G, editors. Hematology- latest research and clinical advances [Internet]. IntechOpen: London; 2018. pp. 155–85.

Google Scholar 

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