Nattel S, Guasch E, Savelieva I, et al. Early management of atrial fibrillation to prevent cardiovascular complications. Eur Heart J. 2014;35(22):1448–56. https://doi.org/10.1093/eurheartj/ehu028.
January CT, Wann LS, Alpert JS, et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014;64(21):e1–76. https://doi.org/10.1016/j.jacc.2014.03.022.
Lip GY, Nieuwlaat R, Pisters R, Lane DA, Crijns HJ. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation. Chest. 2010;137(2):263–72. https://doi.org/10.1378/chest.09-1584.
Pisters R, Lane DA, Nieuwlaat R, de Vos CB, Crijns HJ, Lip GY. A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest. 2010;138(5):1093–100. https://doi.org/10.1378/chest.10-0134.
Hamatani Y, Ogawa H, Uozumi R, et al. Low body weight is associated with the incidence of stroke in atrial fibrillation patients - insight from the Fushimi AF Registry. Circ J. 2015;79(5):1009–17. https://doi.org/10.1253/circj.CJ-14-1245.
Kodani E, Atarashi H, Inoue H, et al. Impact of creatinine clearance on outcomes in patients with non-valvular atrial fibrillation: a subanalysis of the J-RHYTHM Registry. Eur Heart J Qual Care Clin Outcomes. 2018;4(1):59–68. https://doi.org/10.1093/ehjqcco/qcx032.
Abe M, Ogawa H, Ishii M, et al. Relation of stroke and major bleeding to creatinine clearance in patients with atrial fibrillation (from the Fushimi AF Registry). Am J Cardiol. 2017;119(8):1229–37. https://doi.org/10.1016/j.amjcard.2017.01.005.
Article PubMed CAS Google Scholar
Apostolakis S, Lane DA, Guo Y, Buller H, Lip GY. Performance of the HEMORR(2)HAGES, ATRIA, and HAS-BLED bleeding risk-prediction scores in patients with atrial fibrillation undergoing anticoagulation: the AMADEUS (evaluating the use of SR34006 compared to warfarin or acenocoumarol in patients with atrial fibrillation) study. J Am Coll Cardiol. 2012;60(9):861–7. https://doi.org/10.1016/j.jacc.2012.06.019.
Fang MC, Go AS, Chang Y, et al. A new risk scheme to predict warfarin-associated hemorrhage: the ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) study. J Am Coll Cardiol. 2011;58(4):395–401. https://doi.org/10.1016/j.jacc.2011.03.031.
Article PubMed PubMed Central Google Scholar
O’Brien EC, Simon DN, Thomas LE, et al. The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation. Eur Heart J. 2015;36(46):3258–64. https://doi.org/10.1093/eurheartj/ehv476.
Article PubMed PubMed Central CAS Google Scholar
Goodman SG, Wojdyla DM, Piccini JP, et al. Factors associated with major bleeding events: insights from the ROCKET AF trial (rivaroxaban once-daily oral direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation). J Am Coll Cardiol. 2014;63(9):891–900. https://doi.org/10.1016/j.jacc.2013.11.013.
Westenbrink BD, Kleijn L, de Boer RA, et al. Sustained postoperative anaemia is associated with an impaired outcome after coronary artery bypass graft surgery: insights from the IMAGINE trial. Heart. 2011;97(19):1590–6. https://doi.org/10.1136/heartjnl-2011-300118.
Article PubMed CAS Google Scholar
Reinecke H, Trey T, Wellmann J, et al. Haemoglobin-related mortality in patients undergoing percutaneous coronary interventions. Eur Heart J. 2003;24(23):2142–50. https://doi.org/10.1016/j.ehj.2003.09.008.
Article PubMed CAS Google Scholar
Sabatine MS, Morrow DA, Giugliano RP, et al. Association of hemoglobin levels with clinical outcomes in acute coronary syndromes. Circulation. 2005;111(16):2042–9. https://doi.org/10.1161/01.CIR.0000162477.70955.5F.
Article PubMed CAS Google Scholar
Westenbrink BD, Alings M, Connolly SJ, et al. Anemia predicts thromboembolic events, bleeding complications and mortality in patients with atrial fibrillation: insights from the RE-LY trial. J Thromb Haemost. 2015;13(5):699–707. https://doi.org/10.1111/jth.12874.
Article PubMed CAS Google Scholar
Yeh YH, Chan YH, Chen SW, et al. Oral anticoagulant use for patients with atrial fibrillation with concomitant anemia and/or thrombocytopenia. Am J Med. 2022;135(8):e248–56. https://doi.org/10.1016/j.amjmed.2022.03.011.
Article PubMed CAS Google Scholar
Bonde AN, Blanche P, Staerk L, et al. Oral anticoagulation among atrial fibrillation patients with anaemia: an observational cohort study. Eur Heart J. 2019;40(46):3782–90. https://doi.org/10.1093/eurheartj/ehz155.
Article PubMed CAS Google Scholar
Kodani E, Inoue H, Atarashi H, et al. Impact of hemoglobin concentration and platelet count on outcomes of patients with non-valvular atrial fibrillation: a subanalysis of the J-RHYTHM Registry. Int J Cardiol. 2020;302:81–7. https://doi.org/10.1016/j.ijcard.2019.11.127.
Park J, Cha MJ, Choi YJ, et al. Prognostic efficacy of platelet count in patients with nonvalvular atrial fibrillation. Heart Rhythm. 2019;16(2):197–203. https://doi.org/10.1016/j.hrthm.2018.08.023.
Members AF, Kirchhof P, Benussi S, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: the task force for the management of atrial fibrillation of the European Society of Cardiology (ESC) developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESCEndorsed by the European Stroke Organisation (ESO). Eur Heart J. 2016;74(12):1359.
Ruff CT, Giugliano RP, Braunwald E, et al. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet. 2014;383(9921):955–62. https://doi.org/10.1016/S0140-6736(13)62343-0.
Article PubMed CAS Google Scholar
Xu W, Lv M, Wu S, et al. Severe bleeding risk of direct oral anticoagulants versus vitamin k antagonists for stroke prevention and treatment in patients with atrial fibrillation: a systematic review and network meta-analysis. Cardiovasc Drugs Ther. 2023;37(2):363–77. https://doi.org/10.1007/s10557-021-07232-9.
Article PubMed CAS Google Scholar
Patel MR, Mahaffey KW, Garg J, et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. 2011;365(10):883–91. https://doi.org/10.1056/NEJMoa1009638.
Article PubMed CAS Google Scholar
Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009;361(12):1139–51. https://doi.org/10.1056/NEJMoa0905561.
Article PubMed CAS Google Scholar
Granger CB, Alexander JH, McMurray JJ, et al. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2011;365(11):981–92. https://doi.org/10.1056/NEJMoa1107039.
Article PubMed CAS Google Scholar
Giugliano RP, Ruff CT, Braunwald E, et al. Edoxaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2013;369(22):2093–104. https://doi.org/10.1056/NEJMoa1310907.
Article PubMed CAS Google Scholar
Wang CL, Wu VC, Huang YT, et al. Safety and effectiveness of non-vitamin k antagonist oral anticoagulants for stroke prevention in patients with atrial fibrillation and anemia: a retrospective cohort study. J Am Heart Assoc. 2019;8(9):e012029. https://doi.org/10.1161/JAHA.119.012029.
Article PubMed PubMed Central Google Scholar
Wang CL, Wu VC, Lee CH, et al. Effectiveness and safety of non-vitamin-K antagonist oral anticoagulants versus warfarin in atrial fibrillation patients with thrombocytopenia. J Thromb Thrombolysis. 2019;47(4):512–9. https://doi.org/10.1007/s11239-018-1792-1.
Article PubMed CAS Google Scholar
Nutritional anaemias. Report of a WHO scientific group. World Health Organ Tech Rep Ser. 1968;405:5–37.
Schulman S, Kearon C, Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. J Thromb Haemost. 2005;3(4):692–4. https://doi.org/10.1111/j.1538-7836.2005.01204.x.
Article PubMed CAS Google Scholar
Westenbrink BD, Alings M, Granger CB, et al. Anemia is associated with bleeding and mortality, but not stroke, in patients with atrial fibrillation: Insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial. Am Heart J. 2017;185:140–9. https://doi.org/10.1016/j.ahj.2016.12.008.
Spann AP, Campbell JE, Fitzgibbon SR, et al. The effect of hematocrit on platelet adhesion: experiments and simulations. Biophys J. 2016;111(3):577–88. https://doi.org/10.1016/j.bpj.2016.06.024.
Article PubMed PubMed Central CAS Google Scholar
Mayda-Domaç F, Misirli H, Yilmaz M. Prognostic role of mean platelet volume and platelet count in ischemic and hemorrhagic stroke. J Stroke Cerebrovasc Dis. 2010;19(1):66–72. https://doi.org/10.1016/j.jstrokecerebrovasdis.2009.03.003.
Du J, Wang Q, He B, et al. Association of mean platelet volume and platelet count with the development and prognosis of ischemic and hemorrhagic stroke. Int J Lab Hematol. 2016;38(3):233–9. https://doi.org/10.1111/ijlh.12474.
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