Association of Oral Health with Frailty, Malnutrition Risk and Functional Decline in Hospitalized Older Adults: A Cross-Sectional Study

Peres MA, Macpherson LMD, Weyant RJ, et al. Oral diseases: a global public health challenge. Lancet. 2019;394(10194):249–260. doi:https://doi.org/10.1016/S0140-6736(19)31146-8

Article  PubMed  Google Scholar 

Global oral health status report: towards universal health coverage for oral health by 2030. Geneva: World Health Organization; 2022. https://www.who.int/publications/i/item/9789240061484. Accessed May 10, 2023.

Centers for Disease Control and Prevention. Oral Health Surveillance Report: Trends in Dental Caries and Sealants, Tooth Retention, and Edentulism, United States, 1999–2004 to 2011–2016. Atlanta, GA: Centers for Disease Control and Prevention, US Dept of Health and Human Services; 2019. https://www.cdc.gov/oralhealth/publications/OHSR-2019-dental-carries-adults.html. Accessed May 11, 2023.

Google Scholar 

Kassebaum NJ, Bernabé E, Dahiya M, Bhandari B, Murray CJL, Marcenes W. Global burden of severe periodontitis in 1990–2010: a systematic review and metaregression. J Dent Res. 2014;93(11):1045–1053. doi:https://doi.org/10.1177/0022034514552491

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cassolato SF, Turnbull RS. Xerostomia: clinical aspects and treatment. Gerodontology. 2003;20(2):64–77. doi:https://doi.org/10.1111/j.1741-2358.2003.00064.x

Article  PubMed  Google Scholar 

Kim H, Lee E, Lee SW. Association between oral health and frailty: results from the Korea National Health and Nutrition Examination Survey. BMC Geriatr. 2022;22(1):369. doi:https://doi.org/10.1186/s12877-022-02968-x

Article  PubMed  PubMed Central  Google Scholar 

Kimble R, Papacosta AO, Lennon LT, et al. The Relationship of Oral Health with Progression of Physical Frailty among Older Adults: A Longitudinal Study Composed of Two Cohorts of Older Adults from the United Kingdom and United States. J Am Med Dir Assoc. December 2022:S1525–8610(22)00919–7. doi:https://doi.org/10.1016/j.jamda.2022.11.022

Google Scholar 

Dent E, Lien C, Lim WS, et al. The Asia-Pacific Clinical Practice Guidelines for the Management of Frailty. J Am Med Dir Assoc. 2017 Jul 1;18(7):564–575. doi: https://doi.org/10.1016/j.jamda.2017.04.018.

Article  PubMed  Google Scholar 

Hakeem FF, Bernabé E, Sabbah W. Association Between Oral Health and Frailty Among American Older Adults. J Am Med Dir Assoc. 2021;22(3):559–563.e2. doi:https://doi.org/10.1016/j.jamda.2020.07.023

Article  PubMed  Google Scholar 

Watanabe Y, Hirano H, Arai H, et al. Relationship Between Frailty and Oral Function in Community-Dwelling Elderly Adults. J Am Geriatr Soc. 2017;65(1):66–76. doi:https://doi.org/10.1111/jgs.14355

Article  PubMed  Google Scholar 

Castrejón-Pérez RC, Jiménez-Corona A, Bernabé E, et al. Oral Disease and 3-Year Incidence of Frailty in Mexican Older Adults. J Gerontol A Biol Sci Med Sci. 2017;72(7):951–957. doi:https://doi.org/10.1093/gerona/glw201

PubMed  Google Scholar 

Dibello V, Zupo R, Sardone R, et al. Oral frailty and its determinants in older age: a systematic review. Lancet Healthy Longev. 2021;2(8):e507–e520. doi:https://doi.org/10.1016/S2666-7568(21)00143-4

Article  PubMed  Google Scholar 

Shiraishi A, Yoshimura Y, Wakabayashi H, Tsuji Y, Shimazu S, Jeong S. Impaired oral health status on admission is associated with poor clinical outcomes in post-acute inpatients: A prospective cohort study. Clin Nutr. 2019;38(6):2677–2683. doi:https://doi.org/10.1016/j.clnu.2018.11.020

Article  PubMed  Google Scholar 

Shwe PS, Ward SA, Thein PM, Junckerstorff R. Frailty, oral health and nutrition in geriatrics inpatients: A cross-sectional study. Gerodontology. 2019;36(3):223–228. doi:https://doi.org/10.1111/ger.12397

Article  PubMed  Google Scholar 

Taboza ZA, Costa KL, Silveira VR, et al. Periodontitis, edentulism and glycemic control in patients with type 2 diabetes: a cross-sectional study. BMJ Open Diabetes Res Care. 2018;6(1):e000453. doi:https://doi.org/10.1136/bmjdrc-2017-000453

Article  PubMed  PubMed Central  Google Scholar 

Akar H, Akar GC, Carrero JJ, Stenvinkel P, Lindholm B. Systemic consequences of poor oral health in chronic kidney disease patients. Clin J Am Soc Nephrol. 2011;6(1):218–226. doi:https://doi.org/10.2215/CJN.05470610

Article  PubMed  Google Scholar 

Lewis IK, Hanlon JT, Hobbins MJ, Beck JD. Use of medications with potential oral adverse drug reactions in community-dwelling elderly. Spec Care Dent. 1993;13(4):171–176. doi:https://doi.org/10.1111/j.1754-4505.1993.tb01470.x

Article  CAS  Google Scholar 

Chen X, Kistler CE. Oral Health Care for Older Adults with Serious Illness: When and How? J Am Geriatr Soc. 2015;63(2):375–378. doi:https://doi.org/10.1111/jgs.13240

Article  PubMed  PubMed Central  Google Scholar 

Gibney JM, Wright C, Sharma A, D’Souza M, Naganathan V. The oral health status of older patients in acute care on admission and Day 7 in two Australian hospitals. Age Ageing. 2017;46(5):852–856. doi:https://doi.org/10.1093/ageing/afx085

Article  PubMed  Google Scholar 

Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–383. doi:https://doi.org/10.1016/0021-9681(87)90171-8

Article  CAS  PubMed  Google Scholar 

Wong WC, Sahadevan S, Ding YY, Tan HN, Chan SP. Resource consumption in hospitalised, frail older patients. Ann Acad Med Singapore. 2010;39(11):830–836.

Article  PubMed  Google Scholar 

Rockwood K, Song X, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005;173(5):489–495. doi:https://doi.org/10.1503/cmaj.050051

Article  PubMed  PubMed Central  Google Scholar 

Malnutrition and clinical outcomes in elderly patients from a Singapore acute hospital ❘ QUT ePrints. https://eprints.qut.edu.au/44143/. Accessed October 24, 2021.

Eilers J, Berger AM, Petersen MC. Development, testing, and application of the oral assessment guide. Oncol Nurs Forum. 1988;15(3):325–330.

CAS  PubMed  Google Scholar 

Chong E, Tham A, Chew J, et al. Brief Aids to Guide Clinical Frailty Scale Scoring at the Front Door of Acute Hospitals. J Am Med Dir Assoc. 2021;22(5):1116–1117.e2. doi:https://doi.org/10.1016/j.jamda.2021.02.005

Article  PubMed  Google Scholar 

Katz S. Assessing self-maintenance: activities of daily living, mobility, and instrumental activities of daily living. J Am Geriatr Soc. 1983;31(12):721–727. doi:https://doi.org/10.1111/j.1532-5415.1983.tb03391.x

Article  CAS  PubMed  Google Scholar 

Hakeem FF, Bernabé E, Sabbah W. Association between oral health and frailty: A systematic review of longitudinal studies. Gerodontology. 2019;36(3):205–215. doi:https://doi.org/10.1111/ger.12406

Article  PubMed  Google Scholar 

Yun J, Lee Y. Association between oral health status and handgrip strength in older Korean adults. Eur Geriatr Med. 2020;11(3):459–464. doi:https://doi.org/10.1007/s41999-020-00318-x

Article  PubMed  Google Scholar 

Takeuchi N, Sawada N, Ekuni D, Morita M. Oral Factors as Predictors of Frailty in Community-Dwelling Older People: A Prospective Cohort Study. Int J Environ Res Public Health. 2022;19(3):1145. doi:https://doi.org/10.3390/ijerph19031145

Article  PubMed  PubMed Central  Google Scholar 

Clark D, Kotronia E, Ramsay SE. Frailty, aging, and periodontal disease: Basic biologic considerations. Periodontol 2000. 2021 Oct;87(1):143–156. doi: https://doi.org/10.1111/prd.12380.

Article  PubMed  PubMed Central  Google Scholar 

Tanaka T, Takahashi K, Hirano H, et al. Oral Frailty as a Risk Factor for Physical Frailty and Mortality in Community-Dwelling Elderly. J Gerontol A Biol Sci Med Sci. 2018;73(12):1661–1667. doi:https://doi.org/10.1093/gerona/glx225

Article  PubMed  Google Scholar 

Castrejón-Pérez RC, Borges-Yáñez SA, Gutiérrez-Robledo LM, Avila-Funes JA. Oral health conditions and frailty in Mexican community-dwelling elderly: a cross sectional analysis. BMC Public Health. 2012;12:773. doi:https://doi.org/10.1186/1471-2458-12-773

Article  PubMed  PubMed Central  Google Scholar 

Azzolino D, Passarelli PC, De Angelis P, Piccirillo GB, D’Addona A, Cesari M. Poor Oral Health as a Determinant of Malnutrition and Sarcopenia. Nutrients. 2019;11(12):2898. doi:https://doi.org/10.3390/nu11122898

Article  PubMed  PubMed Central  Google Scholar 

Bellanti F, lo Buglio A, Quiete S, Vendemiale G. Malnutrition in Hospitalized Old Patients: Screening and Diagnosis, Clinical Outcomes, and Management. Nutrients. 2022;14(4):910. doi:https://doi.org/10.3390/nu14040910

Article  PubMed  PubMed Central  Google Scholar 

Wakabayashi H, Kishima M, Itoda M, et al. Diagnosis and Treatment of Sarcopenic Dysphagia: A Scoping Review. Dysphagia. 2021;36(3):523–531. doi:https://doi.org/10.1007/s00455-021-10266-8

Article  PubMed  Google Scholar 

Kojima G, Taniguchi Y, Iwasaki M, Aoyama R, Urano T. Associations between self-reported masticatory dysfunction and frailty: A systematic review and meta-analysis. PLoS ONE. 2022;17(9):e0273812. doi:https://doi.org/10.1371/journal.pone.0273812

Article  CAS  PubMed  PubMed Central  Google Scholar 

Leibovitz A, Plotnikov G, Habot B, Rosenberg M, Segal R. Pathogenic colonization of oral flora in frail elderly patients fed by nasogastric tube or percutaneous enterogastric tube. J Gerontol A Biol Sci Med Sci. 2003;58(1):52–55. doi:https://doi.org/10.1093/gerona/58.1.m52

Article  PubMed  Google Scholar 

Robison R, Focht Garand KL, Affoo R, et al. New horizons in understanding oral health and swallowing function within the context of frailty. Age Ageing. 2023;52(2):afac276. doi:https://doi.org/10.1093/ageing/afac276

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