SFRP1 Expression is Inversely Associated With Metastasis Formation in Canine Mammary Tumours

Sleeckx N, de Rooster H, Veldhuis Kroeze E, et al. Canine Mammary Tumours, an Overview. Reprod Domes Anim. 2011;46(6):1112–31.

Article  CAS  Google Scholar 

Canadas A, Franca M, Pereira C, et al. Canine Mammary Tumors: Comparison of Classification and Grading Methods in a Survival Study. Vet Pathol. 2019;56(2):208–19.

Article  PubMed  Google Scholar 

Kaszak I, Ruszczak A, Kanafa S, et al. Current Biomarkers of Canine Mammary Tumors. Acta Vet Scand. 2018;60(1):66.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Goldschmidt M, Pena L, Rasotto R, et al. Classification and Grading of Canine Mammary Tumors. Vet Pathol. 2011;48(1):117–31.

Article  CAS  PubMed  Google Scholar 

DantasCassali G, CavalheiroBertagnolli A, Ferreira E, et al. Canine Mammary Mixed Tumours: A Review. Vet Med Int. 2012;2012:274608.

Google Scholar 

Nunes FC, Damasceno KA, de Campos CB, et al. Mixed Tumors of the Canine Mammary Glands: Evaluation of Prognostic Factors, Treatment, and Overall Survival. Vet Anim Sci. 2019;7:100039.

Article  PubMed  Google Scholar 

Rasotto R, Berlato D, Goldschmidt MH, et al. Prognostic Significance of Canine Mammary Tumor Histologic Subtypes: An Observational Cohort Study of 229 Cases. Vet Pathol. 2017;54(4):571–8.

Article  PubMed  Google Scholar 

Varallo GR, Gelaleti GB, Maschio-Signorini LB, et al. Prognostic Phenotypic Classification for Canine Mammary Tumors. Oncol Lett. 2019;18(6):6545–53.

CAS  PubMed  PubMed Central  Google Scholar 

Valdivia G, Alonso-Diez Á, Pérez-Alenza D, et al. From Conventional to Precision Therapy in Canine Mammary Cancer: A Comprehensive Review. Frontiers Vet Sci. 2021;8:623800.

Article  Google Scholar 

Kaszak I, Witkowska-Pilaszewicz O, Domrazek K, et al. The Novel Diagnostic Techniques and Biomarkers of Canine Mammary Tumors. Vet Sci. 2022;9(10):526.

Article  PubMed  PubMed Central  Google Scholar 

Howard B, Ashworth A. Signalling Pathways Implicated in Early Mammary Gland Morphogenesis and Breast Cancer. PLoS Genet. 2006;2(8):e112.

Article  PubMed  PubMed Central  Google Scholar 

Lanigan F, O’Connor D, Martin F, et al. Molecular Links Between Mammary Gland Development and Breast Cancer. Cell Mol Life Sci. 2007;64(24):3159–84.

Article  CAS  PubMed  Google Scholar 

Stein T, Price KN, Morris JS, et al. Annexin A8 is Up-regulated During Mouse Mammary Gland Involution and Predicts Poor Survival in Breast Cancer. Clin Cancer Res. 2005;11(19 Pt 1):6872–9.

Article  CAS  PubMed  Google Scholar 

Stein T, Salomonis N, Nuyten DSA, et al. A Mouse Mammary Gland Involution mRNA Signature Identifies Biological Pathways Potentially Associated with Breast Cancer Metastasis. J Mammary Gland Biol Neoplasia. 2009;14(2):99–116.

Article  PubMed  Google Scholar 

Ibrahim AM, Sabet S, El-Ghor AA, et al. Fibulin-2 is Required for Basement Membrane Integrity of Mammary Epithelium. Sci Rep. 2018;8(1):14139.

Article  PubMed  PubMed Central  Google Scholar 

Fata JE, Werb Z, Bissell MJ. Regulation of Mammary Gland Branching Morphogenesis By the Extracellular Matrix and Its Remodeling Enzymes. Breast Cancer Res. 2004;6(1):1–11.

Article  CAS  PubMed  Google Scholar 

Ibrahim AM, Bilsland A, Rickelt S, et al. A Matrisome RNA Signature From Early-pregnancy Mouse Mammary Fibroblasts Predicts Distant Metastasis-free Breast Cancer Survival in Humans. Breast Cancer Res. 2021;23(1):90.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ringnér M, Fredlund E, Häkkinen J, et al. GOBO: Gene Expression-Based Outcome for Breast Cancer Online. PLoS ONE. 2011;6(3):e17911–e17911.

Article  PubMed  PubMed Central  Google Scholar 

Klopfleisch R, Lenze D, Hummel M, et al. Metastatic Canine Mammary Carcinomas Can Be Identified By a Gene Expression Profile That Partly Overlaps With Human Breast Cancer Profiles. BMC Cancer. 2010;10(1):618.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Firth D. Bias Reduction of Maximum-likelihood-estimates. Biometrika. 1993;80(1):27–38.

Article  Google Scholar 

Heinze G, Schemper M. A Solution to the Problem of Separation in Logistic Regression. Stat Med. 2002;21(16):2409–19.

Article  PubMed  Google Scholar 

Detre S, SaclaniJotti G, Dowsett M. A “quickscore” Method for Immunohistochemical Semiquantitation: Validation for Oestrogen Receptor in Breast Carcinomas. J Clin Pathol. 1995;48(9):876–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stoltzfus JC. Logistic Regression: A Brief Primer. Acad Emerg Med. 2011;18(10):1099–104.

Article  PubMed  Google Scholar 

Mansournia MA, Geroldinger A, Greenland S, et al. Separation in Logistic Regression: Causes, Consequences, and Control. Am J Epidemiol. 2018;187(4):864–70.

Article  PubMed  Google Scholar 

Kim T-M, Yang IS, Seung B-J, et al. Cross-species Oncogenic Signatures of Breast Cancer in Canine Mammary Tumors. Nat Commun. 2020;11(1):3616.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Geyer FC, Lacroix-Triki M, Savage K, et al. Beta-Catenin Pathway Activation in Breast Cancer is Associated With Triple-negative Phenotype But Not With CTNNB1 Mutation. Mod Pathol. 2011;24(2):209–31.

Article  CAS  PubMed  Google Scholar 

van der Wal T, van Amerongen R. Walking the Tight Wire Between Cell Adhesion and WNT Signalling: A Balancing Act for Beta-catenin. Open Biol. 2020;10(12):200267.

Article  PubMed  PubMed Central  Google Scholar 

Misdorp W, Else R, Hellmen E, et al. World Health Organization International Histological Classification of Tumors of Domestic Animals. 2nd Series. 1999.

Google Scholar 

Yu F, Rasotto R, Zhang H, et al. Evaluation of Expression of the Wnt Signaling Components in Canine Mammary Tumors Via RT(2) Profiler PCR Array and Immunochemistry Assays. J Vet Sci. 2017;18(3):359–67.

Article  PubMed  PubMed Central  Google Scholar 

Gregory KJ, Roberts AL, Conlon EM, et al. Gene Expression Signature of Atypical Breast Hyperplasia and Regulation By SFRP1. Breast Cancer Res. 2019;21(1):76.

Article  PubMed  PubMed Central  Google Scholar 

Klopocki E, Kristiansen G, Wild PJ, et al. Loss of SFRP1 is Associated With Breast Cancer Progression and Poor Prognosis in Early Stage Tumors. Int J Oncol. 2004;25(3):641–9.

CAS  PubMed  Google Scholar 

Lo PK, Mehrotra J, D’Costa A, et al. Epigenetic Suppression of Secreted Frizzled Related Protein 1 (SFRP1) Expression in Human Breast Cancer. Cancer Biol Ther. 2006;5(3):281–6.

Article  CAS  PubMed  Google Scholar 

Shulewitz M, Soloviev I, Wu T, et al. Repressor Roles for TCF-4 and Sfrp1 in Wnt Signaling in Breast Cancer. Oncogene. 2006;25(31):4361–9.

Article  CAS  PubMed  Google Scholar 

Veeck J, Niederacher D, An H, et al. Aberrant Methylation of the Wnt Antagonist SFRP1 in Breast Cancer is Associated With Unfavourable Prognosis. Oncogene. 2006;25(24):3479–88.

Article  CAS  PubMed  Google Scholar 

Dettogni RS, Stur E, Laus AC, et al. Potential Biomarkers of Ductal Carcinoma in Situ Progression. BMC Cancer. 2020;20(1):119.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vargas AC, McCart Reed AE, Waddell N, et al. Gene Expression Profiling of Tumour Epithelial and Stromal Compartments During Breast Cancer Progression. Breast Cancer Res Treat. 2012;135(1):153–65.

Article  CAS  PubMed  Google Scholar 

Yang ZQ, Liu G, Bollig-Fischer A, et al. Methylation-associated Silencing of SFRP1 With an 8p11-12 Amplification Inhibits Canonical and Non-canonical WNT Pathways in Breast Cancers. Int J Cancer. 2009;125(7):1613–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dennis S, Aikawa M, Szeto W, et al. A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates wnt-1 signaling. J Cell Sci. 1999;112(Pt 21):3815–20.

Article  CAS  PubMed  Google Scholar 

Chim CS, Pang R, Fung TK, et al. Epigenetic Dysregulation of Wnt Signaling Pathway in Multiple Myeloma. Leukemia. 2007;21(12):2527–36.

Article  CAS  PubMed  Google Scholar 

Uren A, R

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