alpha-1,3-glucosyltransferase 8

antisense noncoding RNA at the INK4 locus

antisense oligonucleotides

ataxia-telangiectasia mutated

ataxia telangiectasia and rad3-related protein

bicinchoninic acid assay

circular RNA of alpha-1,3-glucosyltransferase 8

Co-Immunoprecipitation

Dulbecco's Modified Eagle Medium

Enzyme-Linked Immunosorbent Assay

Fluorescence In Situ Hybridization

glyceraldehyde-3-phosphate dehydrogenase

homologous recombination

half-maximal inhibitory concentration

internal ribosome entry site

Liquid Chromatography-Mass Spectrometry

multiplex immunohistochemistry

non-homologous end joining

programmed cell death protein 1

Pancreatic Ductal Adenocarcinoma

programmed death-ligand 1

Patient-Derived Organoid

Patient-Derived Xenograft

RNA Antisense purification

Response Evaluation Criteria in Solid Tumours

RNA Immunoprecipitation

Reverse Transcription quantitative Polymerase Chain Reaction

serine/arginine-rich splicing factor

serine/arginine-rich splicing factor 1

serine/arginine-rich splicing factor 3

serine/arginine-rich splicing factor 5

serine/arginine-rich splicing factor 7

signal transducer and activator of transcription 3

tumor microenvironment

Uniform Manifold Approximation and Projection

phosphorylated histone H2AX