Adornato B, Lampert P (1971) Status spongiosus of nervous tissue. Acta Neuropathol 19:271–289. https://doi.org/10.1007/BF00692148

Article  CAS  PubMed  Google Scholar 

Baker HF, Duchen LW, Jacobs JM, Ridley RM (1990) Spongiform encephalopathy transmitted experimentally from Creutzfeldt-Jakob and familial Gerstmann-Straussler-Scheinker diseases. Brain 113(Pt 6):1891–1909. https://doi.org/10.1093/brain/113.6.1891

Article  PubMed  Google Scholar 

Baringer JR, Prusiner SB (1978) Experimental scrapie in mice: Ultrastructural observations. Ann Neurol 4:205–211. https://doi.org/10.1002/ana.410040303

Article  CAS  PubMed  Google Scholar 

Bassi MT, Bresolin N, Tonelli A, Nazos K, Crippa F, Baschirotto C et al (2004) A novel mutation in the ATP1A2 gene causes alternating hemiplegia of childhood. J Med Genet 41:621–628. https://doi.org/10.1136/jmg.2003.017863

Article  CAS  PubMed  PubMed Central  Google Scholar 

Besnoit C, Morel C (1898) Note sur les lesions nerveuses de la tremblante du mouton. Rev Vet Toulouse 23:397

Google Scholar 

Betmouni S, Clements J, Perry VH (1999) Vacuolation in murine prion disease: an informative artifact. Curr Biol 9:R677–R679. https://doi.org/10.1016/S0960-9822(99)80437-0

Article  CAS  PubMed  Google Scholar 

Bignami A, Palladini G (1966) Experimentally produced cerebral status spongiosus and continuous pseudorhythmic electroencephalographic discharges with a membrane-ATPase inhibitor in the rat. Nature 209:413–414

Article  CAS  PubMed  Google Scholar 

Bignami A, Palladini G, Appicciutoli L, Maccagnani F (1967) Experimental study of cerebral spongiosis. Acta Neuropath: Suppl 3:119–126

Google Scholar 

Bignami A, Parry HB (1971) Aggregations of 35-nanometer particles associated with neuronal cytopathic changes in natural scrapie. Science 171:389–390. https://doi.org/10.1126/science.171.3969.389

Article  CAS  PubMed  Google Scholar 

Budka H (2003) Neuropathology of prion diseases. Br Med Bull 66:121–130. https://doi.org/10.1093/bmb/66.1.121

Article  CAS  PubMed  Google Scholar 

Bury M, Girault A, Megalizzi V, Spiegl-Kreinecker S, Mathieu V, Berger W et al (2013) Ophiobolin A induces paraptosis-like cell death in human glioblastoma cells by decreasing BKCa channel activity. Cell Death Dis 4:e561. https://doi.org/10.1038/cddis.2013.85

Article  CAS  PubMed  PubMed Central  Google Scholar 

Calandriello L, Curini R, Pennisi EM, Palladini G (1995) Spongy state (status spongiosus) and inhibition of Na,K-ATPase: a pathogenetic theory. Med Hypoth 44:173–178

Article  CAS  Google Scholar 

Carroll JA, Race B, Phillips K, Striebel JF, Chesebro B (2017) Statins are ineffective at reducing neuroinflammation or prolonging survival in scrapie-infected mice. J Gen Virol 98:2190–2199. https://doi.org/10.1099/jgv.0.000876

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chai H, Cheng X, Zhou B, Zhao L, Lin X, Huang D et al (2019) Structure-based discovery of a subtype-selective inhibitor targeting a transient receptor potential vanilloid channel. J Med Chem 62:1373–1384. https://doi.org/10.1021/acs.jmedchem.8b01496

Article  CAS  PubMed  Google Scholar 

Challis RC, Ravindra Kumar S, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V (2019) Systemic AAV vectors for widespread and targeted gene delivery in rodents. Nat Protoc 14(2):379–414. https://doi.org/10.1038/s41596-018-0097-3

Article  CAS  PubMed  Google Scholar 

Chow CY, Zhang Y, Dowling JJ, Jin N, Adamska M, Shiga K et al (2007) Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J. Nature 448:68–72. https://doi.org/10.1038/nature05876

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cinarli Yuksel F, Nicolaou P, Spontarelli K, Dohrn MF, Rebelo AP, Koutsou P et al (2023) The phenotypic spectrum of pathogenic ATP1A1 variants expands: the novel p. P600R substitution causes demyelinating Charcot-Marie-Tooth disease. J Neurol 270:2576–2590. https://doi.org/10.1007/s00415-023-11581-w

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cornog JL, Gonatas NK, Feierman JR (1967) Effects of intracerebral injection of ouabain on the fine structure of rat cerebral cortex. Am J Pathol 51:573–590

CAS  PubMed  PubMed Central  Google Scholar 

Dalskov S-M, Immerdal L, Niels-Christiansen L-L, Hansen GH, Schousboe A, Danielsen EM (2005) Lipid raft localization of GABAA receptor and Na+, K+-ATPase in discrete microdomain clusters in rat cerebellar granule cells. Neurochem Int 46:489–499. https://doi.org/10.1016/j.neuint.2004.11.010

Article  CAS  PubMed  Google Scholar 

David-Ferreira JF, David-Ferreira KL, Gibbs CJ, Morris JA (1968) Scrapie in mice: ultrastructural observations in the cerebral cortex. Proc Soc Exp Biol Med 127:313–320. https://doi.org/10.3181/00379727-127-32680

Article  CAS  PubMed  Google Scholar 

DeArmond SJ, Sanchez H, Yehiely F, Qiu Y, Ninchak-Casey A, Daggett V et al (1997) Selective neuronal targeting in prion disease. Neuron 19:1337–1348

Article  CAS  PubMed  Google Scholar 

Dilshara MG, Neelaka Molagoda IM, Prasad Tharanga Jayasooriya RG, Choi YH, Park C, Kim GY (2021) Indirubin-3’-monoxime induces paraptosis in MDA-MB-231 breast cancer cells by transmitting Ca(2+) from endoplasmic reticulum to mitochondria. Arch Biochem Biophys 698:108723. https://doi.org/10.1016/j.abb.2020.108723

Article  CAS  PubMed  Google Scholar 

Dostanic I, Schultz Jel J, Lorenz JN, Lingrel JB (2004) The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart. J Biol Chem 279:54053–54061. https://doi.org/10.1074/jbc.M410737200

Article  CAS  PubMed  Google Scholar 

Eid S, Zhao W, Williams D, Nasser Z, Griffin J, Nagorny P et al (2024) Update on a brain-penetrant cardiac glycoside that can lower cellular prion protein levels in human and guinea pig paradigms. PLoS One 19:e0308821. https://doi.org/10.1371/journal.pone.0308821

Article  CAS  PubMed  PubMed Central  Google Scholar 

Favia M, Gerbino A, Notario E, Tragni V, Sgobba MN, Dell’Aquila ME et al (2022) The non-gastric H(+)/K(+) ATPase (ATP12A) is expressed in mammalian spermatozoa. Int J Mol Sci. https://doi.org/10.3390/ijms23031048

Article  PubMed  PubMed Central  Google Scholar 

Ferguson CJ, Lenk GM, Jones JM, Grant AE, Winters JJ, Dowling JJ et al (2012) Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration. Hum Mol Genet 21:3525–3534. https://doi.org/10.1093/hmg/dds179

Article  CAS  PubMed  PubMed Central  Google Scholar 

Florea M, Nicolaou F, Pacouret S, Zinn EM, Sanmiguel J, Andres-Mateos E, Unzu C, Wagers AJ, Vandenberghe LH (2022) High-efficiency purification of divergent AAV serotypes using AAVX affinity chromatography. Mol Ther Methods Clin Dev 28:146-159. https://doi.org/10.1016/j.omtm.2022.12.009

Article  CAS  Google Scholar 

De Fusco M, Marconi R, Silvestri L, Atorino L, Rampoldi L, Morgante L et al (2003) Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2. Nat Genet 33:192–196. https://doi.org/10.1038/ng1081

Article  CAS  PubMed  Google Scholar 

Gambade A, Zreika S, Guéguinou M, Chourpa I, Fromont G, Bouchet AM et al (2016) Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells. Oncotarget 7: 23785–23800. https://doi.org/10.18632/oncotarget.8122

Goggin K, Bissonnette C, Grenier C, Volkov L, Roucou X (2007) Aggregation of cellular prion protein is initiated by proximity-induced dimerization. J Neurochem 102:1195–1205.