[MIC-Advanced pub] Microbiota and metabolome dynamics induced by Shiga toxin-producing E. coli in an in vitro model of an infant’s colon

1 Departamento de Pediatría y Cirugía Infantil Oriente, CICA Hospital Dr. Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile, 7500539 Santiago, Chile. 2 UMR 454 INRAe, Microbiology, Digestive Environment and Health (MEDIS), Université Clermont Auvergne, F-63000 Clermont-Ferrand, France. 3 APC Microbiome Ireland, University College Cork, T12 YT20 Cork, Ireland. 4 School of Microbiology, University College Cork, T12 K8AF Cork, Ireland. 5 School of Pharmacy, University College Cork, T12 K8AF Cork, Ireland.

 

a Equal contribution as first authors.

b Co-last authors.

Keywords: Shiga toxin-producing Escherichia coli (STEC); diarrhea; gut microbiota; gut metabolome; Toddler artificial colon model (T-ARCOL).
Received originally: 07/10/2024 Received in revised form: 20/12/2024
Accepted: 07/01/2025 Published: 14/04/2025

Correspondence:
Stéphanie Blanquet-Diot, UMR 454 INRAe, Microbiology, Digestive Environment and Health (MEDIS), Université Clermont Auvergne, F-63000 Clermont-Ferrand, France; stephanie.blanquet@uca.fr
Mauricio J. Farfan, Departamento de Pediatría y Cirugía Infantil Oriente, CICA Hospital Dr. Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile, 7500539 Santiago, Chile; mfarfan@uchile.cl

Conflict of interest statement: The authors declare no conflicts of interest. The funders had no role in the study’s design, in the data collection, analyses, or interpretation, in the writing of the manuscript, or in the decision to publish the results.
Please cite this article as: Mariana Izquierdo, Deborah O’Sullivan, Ophélie Uriot, Morgane Brun, Claude Durif, Sylvain Denis, Pablo Gallardo, Cormac G M Gahan, Lucie Etienne-Mesmin, Stéphanie Blanquet-Diot and Mauricio J. Farfan (2025). Microbiota and metabolome dynamics induced by Shiga toxin-producing E. coli in an in vitro model of an infant's colon. Microbial Cell 12: 74-92. doi: 10.15698/mic2025.04.847

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