Rinella ME, Lazarus JV, Ratziu V, Francque SM, Sanyal AJ, Kanwal F, et al. A multisociety Delphi consensus statement on new fatty liver disease nomenclature. Ann Hepatol. 2024;29:101133.
Baumann U, Koot BG, Fitzpatrick E, Mann J, Vajro P, Krag A, et al. Paediatric steatotic liver disease has unique characteristics: a multisociety statement endorsing the new nomenclature. J Pediatr Gastroenterol Nutr. 2024;78:1190–6.
Zhang X, Liu J, Ni Y, Yi C, Fang Y, Ning Q, et al. Global prevalence of overweight and obesity in children and adolescents: a systematic review and meta-analysis. JAMA Pediatr. 2024;178:800–13.
Article PubMed PubMed Central Google Scholar
Zhang X, Wu M, Liu Z, Yuan H, Wu X, Shi T, et al. Increasing prevalence of NAFLD/NASH among children, adolescents and young adults from 1990 to 2017: a population-based observational study. BMJ Open. 2021;11:e042843.
Article PubMed PubMed Central Google Scholar
Obita G, Alkhatib A. Disparities in the prevalence of childhood obesity-related comorbidities: a systematic review. Front Public Health. 2022;10:923744.
Article PubMed PubMed Central Google Scholar
Berardis S, Sokal E. Pediatric non-alcoholic fatty liver disease: an increasing public health issue. Eur J Pediatr. 2014;173:131–9.
Article CAS PubMed Google Scholar
Angulo P. Nonalcoholic fatty liver disease. N Engl J Med. 2002;346:1221–31.
Article CAS PubMed Google Scholar
Lawlor DA, Callaway M, Macdonald-Wallis C, Anderson E, Fraser A, Howe LD, et al. Nonalcoholic fatty liver disease, liver fibrosis, and cardiometabolic risk factors in adolescence: a cross-sectional study of 1874 general population adolescents. J Clin Endocrinol Metab. 2014;99:E410–7.
Article CAS PubMed PubMed Central Google Scholar
Alexander J, Torbenson M, Wu TT, Yeh MM. Non-alcoholic fatty liver disease contributes to hepatocarcinogenesis in non-cirrhotic liver: a clinical and pathological study. J Gastroenterol Hepatol. 2013;28:848–54.
Tovo CV, de Mattos AZ, Coral GP, Branco FS, Suwa E, de Mattos AA. Noninvasive imaging assessment of non-alcoholic fatty liver disease: focus on liver scintigraphy. World J Gastroenterol. 2015;21:4432–9
Feldstein AE, Charatcharoenwitthaya P, Treeprasertsuk S, Benson JT, Enders FB, Angulo P. The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years. Gut. 2009;58:1538–44.
Article CAS PubMed Google Scholar
Westerbacka J, Cornér A, Tiikkainen M, Tamminen M, Vehkavaara S, Häkkinen AM, et al. Women and men have similar amounts of liver and intra-abdominal fat, despite more subcutaneous fat in women: implications for sex differences in markers of cardiovascular risk. Diabetologia. 2004;47:1360–9.
Article CAS PubMed Google Scholar
Fraser A, Longnecker MP, Lawlor DA. Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999–2004. Gastroenterology. 2007;133:1814–20.
Article CAS PubMed Google Scholar
Park HS, Han JH, Choi KM, Kim SM. Relation between elevated serum alanine aminotransferase and metabolic syndrome in Korean adolescents. Am J Clin Nutr. 2005;82:1046–51.
Article CAS PubMed Google Scholar
Monteiro PA, Antunes BDEM, Silveira LS, Christofaro DG, Fernandes RA, Freitas Junior IF. Body composition variables as predictors of NAFLD by ultrasound in obese children and adolescents. BMC Pediatr. 2014;14:25.
Article PubMed PubMed Central Google Scholar
Vajro P, Lenta S, Socha P, Dhawan A, McKiernan P, Baumann U, et al. Diagnosis of nonalcoholic fatty liver disease in children and adolescents: position paper of the ESPGHAN Hepatology Committee. J Pediatr Gastroenterol Nutr. 2012;54:700–13.
Saadeh S, Younossi ZM, Remer EM, Gramlich T, Ong JP, Hurley M, et al. The utility of radiological imaging in nonalcoholic fatty liver disease. Gastroenterology. 2002;123:745–50.
Deng J, Fishbein MH, Rigsby CK, Zhang G, Schoeneman SE, Donaldson JS. Quantitative MRI for hepatic fat fraction and T2* measurement in pediatric patients with non-alcoholic fatty liver disease. Pediatr Radiol. 2014;44:1379–87.
Regnell SE, Peterson P, Trinh L, Broberg P, Leander P, Lernmark Å, et al. Magnetic resonance imaging reveals altered distribution of hepatic fat in children with type 1 diabetes compared to controls. Metabolism. 2015;64:872–8.
Article CAS PubMed Google Scholar
Schwimmer JB, Middleton MS, Behling C, Newton KP, Awai HI, Paiz MN, et al. Magnetic resonance imaging and liver histology as biomarkers of hepatic steatosis in children with nonalcoholic fatty liver disease. Hepatology. 2015;61:1887–95.
Article CAS PubMed Google Scholar
Alkhouri N, Carter-Kent C, Lopez R, Rosenberg WM, Pinzani M, Bedogni G, et al. A combination of the pediatric NAFLD fibrosis index and enhanced liver fibrosis test identifies children with fibrosis. Clin Gastroenterol Hepatol. 2011;9:150–5.
Vos MB, Lavine JE. Dietary fructose in nonalcoholic fatty liver disease. Hepatology. 2013;57:2525–31.
Article CAS PubMed Google Scholar
Vos MB, Kaar JL, Welsh JA, van Horn LV, Feig DI, Anderson CAM, et al. Added sugars and cardiovascular disease risk in children: a scientific statement from the American heart association. Circulation. 2017;135:e1017–34.
Article CAS PubMed Google Scholar
Seligman HK, Laraia BA, Kushel MB. Food insecurity is associated with chronic disease among low-income NHANES participants. J Nutr. 2010;140:304–10.
Article CAS PubMed PubMed Central Google Scholar
Rinella ME, Neuschwander-Tetri BA, Siddiqui MS, Abdelmalek MF, Caldwell S, Barb D, et al. AASLD practice guidance on the clinical assessment and management of nonalcoholic fatty liver disease. Hepatology. 2023;77:1797–835.
Jin R, Le NA, Liu S, Farkas Epperson M, Ziegler TR, Welsh JA, et al. Children with NAFLD are more sensitive to the adverse metabolic effects of fructose beverages than children without NAFLD. J Clin Endocrinol Metab. 2012;97:E1088–98.
Article CAS PubMed PubMed Central Google Scholar
OʼSullivan TA, Oddy WH, Bremner AP, Sherriff JL, Ayonrinde OT, Olynyk JK, et al. Lower fructose intake may help protect against development of nonalcoholic fatty liver in adolescents with obesity. J Pediatr Gastroenterol Nutr. 2014;58:624–31.
Solga S, Alkhuraishe AR, Clark JM, Torbenson M, Greenwald A, Diehl AM, et al. Dietary composition and nonalcoholic fatty liver disease. Dig Dis Sci. 2004;49:1578–83.
Schwimmer JB, Ugalde-Nicalo P, Welsh JA, Angeles JE, Cordero M, Harlow KE, et al. Effect of a low free sugar diet vs usual diet on nonalcoholic fatty liver disease in adolescent boys: a randomized clinical trial. JAMA. 2019;321:256–65.
Article PubMed PubMed Central Google Scholar
Corella D, Carrasco P, Sorlí JV, Estruch R, Rico-Sanz J, Martínez-González MÁ, et al. Mediterranean diet reduces the adverse effect of the TCF7L2-rs7903146 polymorphism on cardiovascular risk factors and stroke incidence: a randomized controlled trial in a high-cardiovascular-risk population. Diabetes Care. 2013;36:3803–11.
Article CAS PubMed PubMed Central Google Scholar
Nobili V, Carter-Kent C, Feldstein AE. The role of lifestyle changes in the management of chronic liver disease. BMC Med. 2011;9:70.
Article PubMed PubMed Central Google Scholar
Cheng X, Guo Q, Ju L, Gong W, Wei X, Xu X, et al. Association between sedentary behavior, screen time and metabolic syndrome among Chinese children and adolescents. BMC Public Health. 2024;24:1715.
Article PubMed PubMed Central Google Scholar
Han AL. Association between non-alcoholic fatty liver disease and dietary habits, stress, and health-related quality of life in Korean adults. Nutrients. 2020;12:E1555.
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