Melatonin Rescues Hyperacetylation of Liver and Impaired Enzymatic Activities of Mitochondrial in IVF Offspring

Dyer S, Chambers GM, de Mouzon J, Nygren KG, Zegers-Hochschild F, Mansour R, et al. International committee for monitoring assisted reproductive technologies world report: assisted reproductive technology 2008, 2009 and 2010. Hum Reprod. 2016;31:1588–609.

Article  CAS  PubMed  Google Scholar 

European Society of Human Reproduction and Embryology. Homepage. 2022.

Ceelen M, van Weissenbruch MM, Roos JC, Vermeiden JPW, van Leeuwen FE, de Waal HADV. Body composition in children and adolescents born after in vitro fertilization or spontaneous conception. J Clin Endocr Metab. 2007;92:3417–23.

Article  CAS  PubMed  Google Scholar 

Boulet SL, Kirby RS, Reefhuis J, Zhang Y, Sunderam S, Cohen B, et al. Assisted reproductive technology and birth defects among liveborn infants in Florida, Massachusetts, and Michigan, 2000–2010. JAMA Pediatr. 2016;170(6):e154934–e154934.

Article  PubMed  PubMed Central  Google Scholar 

Zhu L, Zhang Y, Liu Y, Zhang R, Wu Y, Huang Y, et al. Maternal and live-birth outcomes of pregnancies following assisted reproductive technology: A retrospective cohort study. Sci Rep. 2016;6(1):35141.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang ZR, Wang YY, Lin J, Xu JJ, Ding GL, Huang HF. Genetic and epigenetic risks of assisted reproduction. Best Pract Res Cl Ob. 2017;44:90–104.

Article  Google Scholar 

Hart R, Norman RJ. The longer-term health outcomes for children born as a result of IVF treatment: Part IGeneral health outcomes. Hum Reprod Update. 2013;19:232–43.

Article  CAS  PubMed  Google Scholar 

Zandstra H, van Montfoort APA, Dumoulin JCM, Zimmermann LJI, Touwslager RNM. Increased blood pressure and impaired endothelial function after accelerated growth in IVF/ICSI children. Hum Reprod Open. 2020;2020:hoz037.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Donjacour A, Liu X, Lin W, Simbulan R, Rinaudo PF. In vitro fertilization affects growth and glucose metabolism in a sex-specific manner in an outbred mouse model. Biol Reprod. 2014;90(4):80–1.

Article  PubMed  PubMed Central  Google Scholar 

Simbulan RK, Liu X, Feuer SK, Maltepe E, Donjacour A, Rinaudo P. Adult male mice conceived by in vitro fertilization exhibit increased glucocorticoid receptor expression in fat tissue. J Dev Orig Hlth Dis. 2016;7:73–82.

Article  CAS  Google Scholar 

Rexhaj E, Pireva A, Paoloni-Giacobino A, Allemann Y, Cerny D, Dessen P, et al. Prevention of vascular dysfunction and arterial hypertension in mice generated by assisted reproductive technologies by addition of melatonin to culture media. Am J Physiol Heart Circ Physiol. 2015;309:H1151–6.

Article  CAS  PubMed  Google Scholar 

Jia Y, Liu W, Bai D, Zhang Y, Li Y, Liu Y, et al. Melatonin supplementation in the culture medium rescues impaired glucose metabolism in IVF mice offspring. J Pineal Res. 2022;72:e12778.

Article  CAS  PubMed  Google Scholar 

Yang Q, Vijayakumar A, Kahn BB. Metabolites as regulators of insulin sensitivity and metabolism. Nat Rev Mol Cell Bio. 2018;19:654–72.

Article  CAS  Google Scholar 

Samuel VT, Shulman GI. The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux. J Clin Invest. 2016;126:12–22.

Article  PubMed  PubMed Central  Google Scholar 

Pietrocola F, Demont Y, Castoldi F, Enot D, Durand S, Semeraro M, et al. Metabolic effects of fasting on human and mouse blood in vivo. Autophagy. 2017;13:567–78.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhao SM, Xu W, Jiang WQ, Yu W, Lin Y, Zhang TF, et al. Regulation of cellular metabolism by protein lysine acetylation. Science. 2010;327:1000–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Glozak MA, Sengupta N, Zhang XH, Seto E. Acetylation and deacetylation of non-histone proteins. Gene. 2005;363:15–23.

Article  CAS  PubMed  Google Scholar 

Xiong Y, Guan KL. Mechanistic insights into the regulation of metabolic enzymes by acetylation. J Cell Biol. 2012;198:155–64.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cui XX, Li X, Dong SY, Guo YJ, Liu T, Wu YC. SIRT3 deacetylated and increased citrate synthase activity in PD model. Biochem Bioph Res Co. 2017;484:767–73.

Article  CAS  Google Scholar 

Feng X, Zhang L, Xu S, Shen AZ. ATP-citrate lyase (ACLY) in lipid metabolism and atherosclerosis: An updated review. Prog Lipid Res. 2020;77:101006.

Article  CAS  PubMed  Google Scholar 

Wisniewski JR, Zougman A, Nagaraj N, Mann M. Universal sample preparation method for proteome analysis. Nat Methods. 2009;6:359-U60.

Article  CAS  PubMed  Google Scholar 

Cimen H, Han MJ, Yang YJ, Tong Q, Koc H, Koc EC. Regulation of succinate dehydrogenase activity by sirt3 in mammalian mitochondria. Biochemistry-Us. 2010;49:304–11.

Article  CAS  Google Scholar 

Hallows WC, Lee S, Denu JM. Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc Natl Acad Sci U S A. 2006;103:10230–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Choux C, Petazzi P, Sanchez-Delgado M, Mora JRH, Monteagudo A, Sagot P, et al. The hypomethylation of imprinted genes in IVF/ICSI placenta samples is associated with concomitant changes in histone modifications. Epigenetics-Us. 2020;15:1386–95.

Article  Google Scholar 

Zheng HY, Tang Y, Niu J, Li P, Ye DS, Chen X, et al. Aberrant DNA methylation of imprinted loci in human spontaneous abortions after assisted reproduction techniques and natural conception. Hum Reprod. 2013;28:265–73.

Article  CAS  PubMed  Google Scholar 

Mani S, Ghosh J, Coutifaris C, Sapienza C, Mainigi M. Epigenetic changes and assisted reproductive technologies. Epigenetics-Us. 2020;15:12–25.

Article  Google Scholar 

Liu XZ, Zhao DM, Zheng YM, Wang LY, Qian YL, Xu CM, et al. Expression of histone acetyltransferase GCN5 and histone deacetylase 1 in the cultured mouse preimplantation embryos. Curr Pharm Design. 2014;20:1772–7.

Article  CAS  Google Scholar 

Franciosi F, Lodde V, Goudet G, Duchamp G, Deleuze S, Douet C, et al. Changes in histone H4 acetylation during in vivo versus in vitro maturation of equine oocytes. Mol Hum Reprod. 2012;18:243–52.

Article  CAS  PubMed  Google Scholar 

Zuo ZZ, Niu ZH, Liu ZQ, Ma JK, Qu PX, Qiao F, et al. The effects of glycine-glutamine dipeptide replaced L-glutamine on bovine parthenogenetic and IVF embryo development. Theriogenology. 2020;141:82–90.

Article  CAS  PubMed  Google Scholar 

Lira-Albarran S, Liu XW, Lee SH, Rinaudo P. DNA methylation profile of liver of mice conceived by in vitro fertilization. J Dev Orig Hlth Dis. 2022;13:358–66.

Article  CAS  Google Scholar 

Alquezar C, Arya S, Kao AW. Tau post-translational modifications: dynamic transformers of tau function, degradation, and aggregation. Front Neurol. 2021;11:595532.

Article  PubMed  PubMed Central  Google Scholar 

Yang XJ, Seto E. Lysine acetylation: Codified crosstalk with other posttranslational modifications. Mol Cell. 2008;31:449–61.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gao L, Cueto MA, Asselbergs F, Atadja P. Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family. J Biol Chem. 2002;277:25748–55.

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