Fundamentals of fetal brain MRI: indications, technique, and normal anatomy

Kline-Fath BM (2019) Ultrasound and MR imaging of the normal fetal brain. Neuroimaging Clin N Am. 29:339–356

Article  PubMed  Google Scholar 

ACR Committee on MR Safety, Greenberg TD, Hoff MN, Gilk TB, Jackson EF, Kanal E, et al. ACR guidance document on MR safe practices: updates and critical information 2019. J Magn Reson Imaging JMRI. 2020;51:331–338

Tocchio S, Kline-Fath B, Kanal E et al (2015) MRI evaluation and safety in the developing brain. Semin Perinatol. 39:73–104

Article  PubMed  PubMed Central  Google Scholar 

Saleem SN (2013) Fetal magnetic resonance imaging (MRI): a tool for a better understanding of normal and abnormal brain development. J Child Neurol. 28:890–908

Article  PubMed  Google Scholar 

Guimaraes CVA, Dahmoush HM (2022) Fetal brain anatomy. Neuroimaging Clin N Am. 32:663–681

Article  PubMed  Google Scholar 

Chartier AL, Bouvier MJ, McPherson DR et al (2019) The safety of maternal and fetal MRI at 3 T. AJR Am J Roentgenol. 213:1170–1173

Article  PubMed  Google Scholar 

Ray JG, Vermeulen MJ, Bharatha A, et al (2016) Association between MRI exposure during pregnancy and fetal and childhood outcomes. JAMA. 316:952–961

Article  PubMed  Google Scholar 

Krishnamurthy U, Neelavalli J, Mody S, et al (2015) MR imaging of the fetal brain at 1.5T and 3.0T field strengths: comparing specific absorption rate (SAR) and image quality. J Perinat Med. 43:209–220

Article  PubMed  PubMed Central  Google Scholar 

Machado-Rivas F, Cortes-Albornoz MC, Afacan O et al. (2023) Fetal MRI at 3 T: principles to optimize success. Radiogr Rev Publ Radiol Soc N Am Inc. 43:e220141

Yamashita Y, Namimoto T, Abe Y et al (1997) MR imaging of the fetus by a HASTE sequence. AJR Am J Roentgenol. 168:513–513

Article  CAS  PubMed  Google Scholar 

Manganaro L, Bernardo S, Antonelli A et al (2017) Fetal MRI of the central nervous system: state-of-the-art. Eur J Radiol. 93:273–283

Article  PubMed  Google Scholar 

Sun T, Jiang L, Zhang Z et al (2020) Feasibility of free-breathing T1-weighted 3D radial VIBE for fetal MRI in various anomalies. Magn Reson Imaging. 69:57–64

Article  PubMed  Google Scholar 

Prayer D, Brugger PC, Prayer L (2004) Fetal MRI: techniques and protocols. Pediatr Radiol. 34:685–693

Article  PubMed  Google Scholar 

Blondiaux E, Chougar L, Gelot A et al. (2018) Developmental patterns of fetal fat and corresponding signal on T1-weighted magnetic resonance imaging. Pediatr Radiol. 48:317–324

Chougar L, Blondiaux E, Moutard ML et al. (2018) Variability of T1-weighted signal intensity of pericallosal lipomas in the fetus. Pediatr Radiol. 48:383–391

Prayer D, Barkovich AJ, Kirschner DA et al (2001) Visualization of nonstructural changes in early white matter development on diffusion-weighted MR images: evidence supporting premyelination anisotropy. AJNR Am J Neuroradiol. 22:1572–1576

CAS  PubMed  PubMed Central  Google Scholar 

Righini A, Bianchini E, Parazzini C et al (2003) Apparent diffusion coefficient determination in normal fetal brain: a prenatal MR imaging study. AJNR Am J Neuroradiol. 24:799–804

PubMed  PubMed Central  Google Scholar 

Diogo MC, Prayer D, Gruber GM et al (2019) Echo-planar FLAIR sequence improves subplate visualization in fetal MRI of the brain. Radiology. 292:159–169

Article  PubMed  Google Scholar 

Gholipour A, Estroff JA, Barnewolt CE et al (2011) Fetal brain volumetry through MRI volumetric reconstruction and segmentation. Int J Comput Assist Radiol Surg. 6:329–339

Article  PubMed  Google Scholar 

Thomason ME, Dassanayake MT, Shen S, et al (2013) Cross-hemispheric functional connectivity in the human fetal brain. Sci Transl Med. 5:173ra24

Article  PubMed  PubMed Central  Google Scholar 

Triulzi F, Manganaro L, Volpe P (2011) Fetal magnetic resonance imaging: indications, study protocols and safety. Radiol Med (Torino). 116:337–350

Article  CAS  PubMed  Google Scholar 

Yen CJ, Mehollin-Ray AR, Bernardo F, et al (2019) Correlation between maternal meal and fetal motion during fetal MRI. Pediatr Radiol. 49:46–50

Article  PubMed  Google Scholar 

Moltoni G, Talenti G, Righini A (2021) Brain fetal neuroradiology: a beginner’s guide. Transl Pediatr. 10:1065–1077

Article  PubMed  PubMed Central  Google Scholar 

Prayer D, Kasprian G, Krampl E, et al (2006) MRI of normal fetal brain development. Eur J Radiol. 57:199–216

Article  PubMed  Google Scholar 

Maas LC, Mukherjee P, Carballido-Gamio J, et al (2004) Early laminar organization of the human cerebrum demonstrated with diffusion tensor imaging in extremely premature infants. NeuroImage. 22:1134–1140

Article  PubMed  Google Scholar 

Glenn OA (2009) Normal development of the fetal brain by MRI. Semin Perinatol. 33:208–219

Article  PubMed  Google Scholar 

Lan LM, Yamashita Y, Tang Y, et al (2000) Normal fetal brain development: MR imaging with a half-Fourier rapid acquisition with relaxation enhancement sequence. Radiology. 215:205–210

Article  CAS  PubMed  Google Scholar 

Schneider JF, Confort-Gouny S, Le Fur Y, et al (2007) Diffusion-weighted imaging in normal fetal brain maturation. Eur Radiol. 17:2422–2429

Article  CAS  PubMed  Google Scholar 

Garel C, Chantrel E, Elmaleh M, et al (2003) Fetal MRI: normal gestational landmarks for cerebral biometry, gyration and myelination. Childs Nerv Syst ChNS Off J Int Soc Pediatr Neurosurg. 19:422–425

Article  Google Scholar 

Weisstanner C, Kasprian G, Gruber GM, et al (2015) MRI of the fetal brain. Clin Neuroradiol. 25(Suppl 2):189–196

Article  PubMed  Google Scholar 

Kasprian G, Langs G, Brugger PC, et al (2011) The prenatal origin of hemispheric asymmetry: an in utero neuroimaging study. Cereb Cortex. 21:1076–1083

Article  PubMed  Google Scholar 

Habas PA, Scott JA, Roosta A, et al (2012) Early folding patterns and asymmetries of the normal human brain detected from in utero MRI. Cereb Cortex. 22:13–25

Article  PubMed  Google Scholar 

Siala S, Homen D, Smith B, Guimaraes C (2023) Imaging of the septum pellucidum: normal, variants and pathology. Br J Radiol. 96:20221058

Article  PubMed  PubMed Central  Google Scholar 

Griffiths PD, Batty R, Reeves MJ, Connolly DJA (2009) Imaging the corpus callosum, septum pellucidum and fornix in children: normal anatomy and variations of normality. Neuroradiology. 51(5):337–345

Article  PubMed  Google Scholar 

Rakic P, Yakovlev PI (1968) Development of the corpus callosum and cavum septi in man. J Comp Neurol. 132(1):45–72

Article  CAS  PubMed  Google Scholar 

Jou HJ, Shyu MK, Wu SC, et al (1998) Ultrasound measurement of the fetal cavum septi pellucidi. Ultrasound Obstet Gynecol. 12(6):419–421

Article  CAS  PubMed  Google Scholar 

Nagaraj UD, Calvo-Garcia MA, Kline-Fath BM (2018) Abnormalities associated with the cavum septi pellucidi on fetal MRI: what radiologists need to know. AJR Am J Roentgenol. 210(5):989–997

Article  PubMed  Google Scholar 

Harreld JH, Bhore R, Chason DP, Twickler DM (2011) Corpus callosum length by gestational age as evaluated by fetal MR imaging. AJNR Am J Neuroradiol. 32(3):490–494

Article  CAS  PubMed  PubMed Central  Google Scholar 

Farrell TA, Hertzberg BS, Kliewer MA, et al (1994) Fetal lateral ventricles: reassessment of normal values for atrial diameter at US. Radiology. 193(2):409–411

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