Young infants’ exposure to parabens: lotion use as a potential source of exposure

Final Report on the Safety Assessment of Methylparaben, Ethylparaben, Propylparaben, and Butylparaben. J Am Coll Toxicol. 1984 [cited 2024 Sep 11];3. Available from: https://journals.sagepub.com/doi/epdf/10.3109/10915818409021274.

Błędzka D, Gromadzińska J, Wąsowicz W. Parabens. From environmental studies to human health. Environ Int. 2014;67:27–42.

Article  PubMed  Google Scholar 

Nowak K, Ratajczak–Wrona W, Górska M, Jabłońska E. Parabens and their effects on the endocrine system. Mol Cell Endocrinol. 2018;474:238–51.

Article  CAS  PubMed  Google Scholar 

Smarr MM, Sundaram R, Honda M, Kannan K, Louis GMB. Urinary concentrations of parabens and other antimicrobial chemicals and their association with couples’ fecundity. Environ Health Perspect. 2017;125:730–6.

Article  CAS  PubMed  Google Scholar 

Sun L, Yu T, Guo J, Zhang Z, Hu Y, Xiao X, et al. The estrogenicity of methylparaben and ethylparaben at doses close to the acceptable daily intake in immature Sprague-Dawley rats. Sci Rep. 2016;6:25173.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thürmann L, Herberth G, Seiwert B, Schlittenbauer L, Rolle-Kampczyk U, Röder S, et al. Prenatal paraben exposure and atopic dermatitis-related outcomes among children. Allergy. 2021;76:3122–32.

Article  PubMed  Google Scholar 

Engeli RT, Rohrer SR, Vuorinen A, Herdlinger S, Kaserer T, Leugger S, et al. Interference of Paraben compounds with estrogen metabolism by inhibition of 17β-Hydroxysteroid Dehydrogenases. Int J Mol Sci. 2017;18:2007.

Article  PubMed  PubMed Central  Google Scholar 

Lu S, Ren L, Liu Y, Ma H, Liu S, Zhu Z, et al. Urinary parabens in children from South China: Implications for human exposure and health risks. Environ Pollut. 2019;254:113007.

Article  CAS  PubMed  Google Scholar 

Nguyen HT, Isobe T, Iwai-Shimada M, Takagi M, Ueyama J, Oura K, et al. Urinary concentrations and elimination half-lives of parabens, benzophenones, bisphenol and triclosan in Japanese young adults. Chemosphere. 2024;349:140920.

Article  CAS  PubMed  Google Scholar 

Liu W, Zhou Y, Li J, Sun X, Liu H, Jiang Y, et al. Parabens exposure in early pregnancy and gestational diabetes mellitus. Environ Int. 2019;126:468–75.

Article  CAS  PubMed  Google Scholar 

Nishihama Y, Yoshinaga J, Iida A, Konishi S, Imai H, Yoneyama M, et al. Association between paraben exposure and menstrual cycle in female university students in Japan. Reprod Toxicol. 2016;63:107–13.

Article  CAS  PubMed  Google Scholar 

Yu Y, Li W, Lu S, Wu S, Wang F, Tse LA, et al. Urinary parabens in adults from South China: Implications for human exposure and health risks. Ecotoxicol Environ Saf. 2019;182:109419.

Article  CAS  PubMed  Google Scholar 

Gosens I, Delmaar CJE, ter Burg W, de Heer C, Schuur AG. Aggregate exposure approaches for parabens in personal care products: a case assessment for children between 0 and 3 years old. J Expo Sci Environ Epidemiol. 2014;24:208–14.

Article  CAS  PubMed  Google Scholar 

Hager E, Chen J, Zhao L. Minireview: parabens exposure and breast cancer. Int J Environ Res Public Health. 2022;19:1873.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Soni MG, Carabin IG, Burdock GA. Safety assessment of esters of p-hydroxybenzoic acid (parabens). Food Chem Toxicol. 2005;43:985–1015.

Article  CAS  PubMed  Google Scholar 

Levasseur JL, Hammel SC, Hoffman K, Phillips AL, Zhang S, Ye X, et al. Young children’s exposure to phenols in the home: Associations between house dust, hand wipes, silicone wristbands, and urinary biomarkers. Environ Int. 2021;147:106317.

Article  CAS  PubMed  Google Scholar 

Zhang D, Xiao J, Xiao Q, Chen Y, Li X, Zheng Q, et al. Infant exposure to parabens, triclosan, and triclocarban via breastfeeding and formula supplementing in southern China. Sci Total Environ. 2023;858:159820.

Article  CAS  PubMed  Google Scholar 

Czarczyńska-Goślińska B, Grześkowiak T, Frankowski R, Lulek J, Pieczak J, Zgoła-Grześkowiak A. Determination of bisphenols and parabens in breast milk and dietary risk assessment for Polish breastfed infants. J Food Compos Anal. 2021;98:103839.

Article  Google Scholar 

Freire C, Molina-Molina JM, Iribarne-Durán LM, Jiménez-Díaz I, Vela-Soria F, Mustieles V, et al. Concentrations of bisphenol A and parabens in socks for infants and young children in Spain and their hormone-like activities. Environ Int. 2019;127:592–600.

Article  CAS  PubMed  Google Scholar 

Guo Y, Kannan K. A Survey of phthalates and parabens in personal care products from the United States and its implications for human exposure. Environ Sci Technol. 2013;47:14442–9.

Article  CAS  PubMed  Google Scholar 

Calafat AM, Ye X, Wong LY, Bishop AM, Needham LL. Urinary concentrations of four parabens in the U.S. population: NHANES 2005–2006. Environ Health Perspect. 2010;118:679–85.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hoffman K, Hammel SC, Phillips AL, Lorenzo AM, Chen A, Calafat AM, et al. Biomarkers of exposure to SVOCs in children and their demographic associations: The TESIE Study. Environ Int. 2018;119:26–36.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee S, Karvonen-Gutierrez C, Mukherjee B, Herman WH, Park SK. Race-specific associations of urinary phenols and parabens with adipokines in midlife women: The Study of Women’s Health Across the Nation (SWAN). Environ Pollut. 2022;303:119164.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Preston EV, Chan M, Nozhenko K, Bellavia A, Grenon MC, Cantonwine DE, et al. Socioeconomic and racial/ethnic differences in use of endocrine-disrupting chemical-associated personal care product categories among pregnant women. Environ Res. 2021;198:111212.

Article  CAS  PubMed  PubMed Central  Google Scholar 

James-Todd T, Senie R, Terry MB. Racial/Ethnic differences in hormonally-active hair product use: a plausible risk factor for health disparities. J Immigr Minority Health. 2012;14:506–11.

Article  Google Scholar 

Scharf RJ, Scharf GJ, Stroustrup A. Developmental milestones. Pediatr Rev. 2016;37:25–38.

Article  PubMed  Google Scholar 

Carroquino MJ, Posada M, Landrigan PJ. Environmental toxicology: children at risk. Environ Toxicol. 2012;4:239–91.

Google Scholar 

Hauptman M, Woolf AD. Childhood ingestions of environmental toxins: what are the risks? Pediatr Ann. 2017;46:e466–71.

Article  PubMed  PubMed Central  Google Scholar 

Hammel SC, Zhang S, Lorenzo AM, Eichner B, Stapleton HM, Hoffman K. Young infants’ exposure to organophosphate esters: Breast milk as a potential source of exposure. Environ Int. 2020;143:106009.

Article  CAS  PubMed  Google Scholar 

Kang S, Kim S, Park J, Kim HJ, Lee J, Choi G, et al. Urinary paraben concentrations among pregnant women and their matching newborn infants of Korea, and the association with oxidative stress biomarkers. Sci Total Environ. 2013;461–462:214–21.

Article  PubMed  Google Scholar 

Levasseur JL, Hoffman K, Zhang S, Cooper EM, Stapleton HM. Monitoring human exposure to four parabens and triclosan: comparing silicone wristbands with spot urine samples as predictors of internal dose. J Expo Sci Environ Epidemiol. 2024;4:1–9.

Google Scholar 

Graul RJ, Stanley RL. Specific gravity adjustment of urine analysis results. Am Ind Hyg Assoc J. 1982;43:863.

Article  CAS  PubMed  Google Scholar 

Antweiler RC, Taylor HE. Evaluation of statistical treatments of left-censored environmental data using coincident uncensored Data Sets: I. Summary statistics. Environ Sci Technol. 2008;42:3732–8.

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