Tifoun N, De Las Heras JM, Guillaume A, Bouleau S, Mignotte B, Le Floch N. Insights into the roles of the sideroflexins/SLC56 family in iron homeostasis and iron-sulfur biogenesis. Biomedicines. 2021;9(2):103.
Article CAS PubMed PubMed Central Google Scholar
Attwood MM, Schioth HB. Characterization of five transmembrane proteins: with focus on the tweety, sideroflexin, and YIP1 domain families. Front Cell Dev Biol. 2021;9:708754.
Article PubMed PubMed Central Google Scholar
Kory N, Wyant GA, Prakash G, Uit de Bos J, Bottanelli F, Pacold ME, Chan SH, Lewis CA, Wang T, Keys HR, et al. SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism. Science. 2018;362:6416.
Paul BT, Tesfay L, Winkler CR, Torti FM, Torti SV. Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes. Sci Rep. 2019;9(1):19634.
Article CAS PubMed PubMed Central Google Scholar
Jackson TD, Crameri JJ, Muellner-Wong L, Frazier AE, Palmer CS, Formosa LE, Hock DH, Fujihara KM, Stait T, Sharpe AJ, et al. Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module. Proc Natl Acad Sci USA. 2022;119(13):e2115566119.
Article CAS PubMed PubMed Central Google Scholar
Tesfay L, Paul BT, Hegde P, Brewer M, Habbani S, Jellison E, Moore T, Wu H, Torti SV, Torti FM. Complementary anti-cancer pathways triggered by inhibition of sideroflexin 4 in ovarian cancer. Sci Rep. 2022;12(1):19936.
Article CAS PubMed PubMed Central Google Scholar
Zhang H, Meng L, Liu Y, Jiang J, He Z, Qin J, Wang C, Yang M, He K, Yang J, et al. Sfxn5 regulation of actin polymerization for neutrophil spreading depends on a citrate-cholesterol-PI(4,5)P2 pathway. J Immunol. 2023;211(3):462–73.
Article CAS PubMed Google Scholar
Rafikova G, Gilyazova I, Enikeeva K, Pavlov V, Kzhyshkowska J. Prostate cancer: genetics, epigenetics and the need for immunological biomarkers. Int J Mol Sci. 2023;24(16):12797.
Article CAS PubMed PubMed Central Google Scholar
Boehm BE, York ME, Petrovics G, Kohaar I, Chesnut GT. Biomarkers of aggressive prostate cancer at diagnosis. Int J Mol Sci. 2023;24(3):2185.
Article CAS PubMed PubMed Central Google Scholar
Uhr A, Glick L, Gomella LG. An overview of biomarkers in the diagnosis and management of prostate cancer. Can J Urol. 2020;27(S3):24–7.
Kohaar I, Petrovics G, Srivastava S. A rich array of prostate cancer molecular biomarkers: opportunities and challenges. Int J Mol Sci. 2019;20(8):1813.
Article CAS PubMed PubMed Central Google Scholar
Oudes AJ, Campbell DS, Sorensen CM, Walashek LS, True LD, Liu AY. Transcriptomes of human prostate cells. BMC Genom. 2006;7:92.
Ghandi M, Huang FW, Jane-Valbuena J, Kryukov GV, Lo CC, McDonald ER 3rd, Barretina J, Gelfand ET, Bielski CM, Li H, et al. Next-generation characterization of the cancer cell line encyclopedia. Nature. 2019;569(7757):503–8.
Article CAS PubMed PubMed Central Google Scholar
Xu H, Liu W, He C, Mirza M, Li B. Aberrant expression of multiple glycolytic enzyme genes is significantly associated with disease progression and survival outcomes in prostate cancers. Am J Clin Exp Urol. 2023;11(6):530–41.
PubMed PubMed Central Google Scholar
Huang H, Song S, Liu W, Ye S, Bao Y, Mirza M, Li B, Huang J, Zhu R, Lian H. Expressions of glucose transporter genes are diversely attenuated and significantly associated with prostate cancer progression. Am J Clin Exp Urol. 2023;11(6):578–93.
CAS PubMed PubMed Central Google Scholar
He C, Liu W, Sun J, Zhang D, Li B. Jumonji domain-containing protein RIOX2 is overexpressed and associated with worse survival outcomes in prostate cancers. Front Oncol. 2023;13:1087082.
Article CAS PubMed PubMed Central Google Scholar
Huang J, Liu W, Zhang D, Lin B, Li B. TMEM158 expression is negatively regulated by AR signaling and associated with favorite survival outcomes in prostate cancers. Front Oncol. 2022;12:1023455.
Article CAS PubMed PubMed Central Google Scholar
Huang J, Liu W, Lin BY, Li JC, Lu J, Li BY. Scaffold protein MAPK8IP2 expression is a robust prognostic factor in prostate cancer associated with AR signaling activity. Asian J Androl. 2023;25(2):198–207.
Article CAS PubMed Google Scholar
Tao C, Liu W, Yan X, Yang M, Yao S, Shu Q, Li B, Zhu R. PAQR5 expression is suppressed by TGFbeta1 and associated with a poor survival outcome in renal clear cell carcinoma. Front Oncol. 2021;11:827344.
Article CAS PubMed Google Scholar
Yang M, Li JC, Tao C, Wu S, Liu B, Shu Q, Li B, Zhu R. PAQR6 upregulation is associated with AR signaling and unfavorite prognosis in prostate cancers. Biomolecules. 2021;11(9):1383.
Article PubMed PubMed Central Google Scholar
Huang J, Liu W, Song S, Li JC, Gan K, Shen C, Holzbeierlein J, Li B. The iron-modulating hormone hepcidin is upregulated and associated with poor survival outcomes in renal clear cell carcinoma. Front Pharmacol. 2022;13:1080055.
Article CAS PubMed PubMed Central Google Scholar
Wang J, Liu W, Li JC, Li M, Li B, Zhu R. Hepcidin downregulation correlates with disease aggressiveness and immune infiltration in liver cancers. Front Oncol. 2021;11:714756.
Article CAS PubMed PubMed Central Google Scholar
Menyhart O, Nagy A, Gyorffy B. Determining consistent prognostic biomarkers of overall survival and vascular invasion in hepatocellular carcinoma. R Soc Open Sci. 2018;5(12):181006.
Article CAS PubMed PubMed Central Google Scholar
Abida W, Cyrta J, Heller G, Prandi D, Armenia J, Coleman I, Cieslik M, Benelli M, Robinson D, Van Allen EM, et al. Genomic correlates of clinical outcome in advanced prostate cancer. Proc Natl Acad Sci USA. 2019;116(23):11428–36.
Article CAS PubMed PubMed Central Google Scholar
Cheng S, Li L, Yeh Y, Shi Y, Franco O, Corey E, Yu X. Unveiling novel double-negative prostate cancer subtypes through single-cell RNA sequencing analysis. NPJ Precis Oncol. 2024;8(1):171.
Article CAS PubMed PubMed Central Google Scholar
Wang XD, Wang BE, Soriano R, Zha J, Zhang Z, Modrusan Z, Cunha GR, Gao WQ. Expression profiling of the mouse prostate after castration and hormone replacement: implication of H-cadherin in prostate tumorigenesis. Differentiation. 2007;75(3):219–34.
Article CAS PubMed Google Scholar
Sun Y, Wang BE, Leong KG, Yue P, Li L, Jhunjhunwala S, Chen D, Seo K, Modrusan Z, Gao WQ, et al. Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy. Cancer Res. 2012;72(2):527–36.
Article CAS PubMed Google Scholar
Terada N, Shimizu Y, Kamba T, Inoue T, Maeno A, Kobayashi T, Nakamura E, Kamoto T, Kanaji T, Maruyama T, et al. Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model. Cancer Res. 2010;70(4):1606–15.
Article CAS PubMed Google Scholar
Pacini C, Dempster JM, Boyle I, Goncalves E, Najgebauer H, Karakoc E, van der Meer D, Barthorpe A, Lightfoot H, Jaaks P, et al. Integrated cross-study datasets of genetic dependencies in cancer. Nat Commun. 2021;12(1):1661.
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