Burnett AL, Bivalacqua TJ (2007) Priapism: current principles and practice. Urol Clin North Am 34(4):631–642. https://doi.org/10.1016/J.UCL.2007.08.006
Eland IA, Van der Lei J, Stricker BHC, Sturkenboom MJCM (2001) Incidence of priapism in the general population. Urology 57(5):970–972. https://doi.org/10.1016/S0090-4295(01)00941-4
Article CAS PubMed Google Scholar
Broderick GA, Kadioglu A, Bivalacqua TJ, Ghanem H, Nehra A, Shamloul R (2010) Priapism: pathogenesis, epidemiology, and management. J Sex Med 7(1 Pt 2):476–500. https://doi.org/10.1111/J.1743-6109.2009.01625.X
Spycher MA, Hauri D (1986) The ultrastructure of the erectile tissue in priapism. J Urol 135(1):142–147. https://doi.org/10.1016/S0022-5347(17)45549-2
Article CAS PubMed Google Scholar
Wen J, Jiang X, Dai Y et al (2010) Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A2B adenosine receptor signaling. FASEB J 24(3):740–749. https://doi.org/10.1096/FJ.09-144147
Article CAS PubMed PubMed Central Google Scholar
Egydio PH, Kuehhas FE (2013) Treatments for fibrosis of the corpora cavernosa. Arab J Urol 11(3):294–298. https://doi.org/10.1016/J.AJU.2013.05.004
Article PubMed PubMed Central Google Scholar
El-Sakka AI, Yassin AA (2010) Amelioration of penile fibrosis: myth or reality. J Androl 31(4):324–335. https://doi.org/10.2164/JANDROL.109.008730
Article CAS PubMed Google Scholar
Ryu JK, Kim DH, Song KM et al (2016) Intracavernous delivery of clonal mesenchymal stem cells rescues erectile function in the streptozotocin-induced diabetic mouse. Andrology 4(1):172–184. https://doi.org/10.1111/ANDR.12138
Article CAS PubMed Google Scholar
Yang J, Zhang Y, Zang G et al (2018) Adipose-derived stem cells improve erectile function partially through the secretion of IGF-1, bFGF, and VEGF in aged rats. Andrology 6(3):498–509. https://doi.org/10.1111/ANDR.12483
Article CAS PubMed Google Scholar
Albersen M, Fandel TM, Lin G et al (2010) Injections of adipose tissue-derived stem cells and stem cell lysate improve recovery of erectile function in a rat model of cavernous nerve injury. J Sex Med 7(10):3331–3340. https://doi.org/10.1111/J.1743-6109.2010.01875.X
Gokce A, AbdElmageed ZY, Lasker GF et al (2014) Adipose tissue-derived stem cell therapy for prevention and treatment of erectile dysfunction in a rat model of Peyronie’s disease. Andrology 2(2):244–251. https://doi.org/10.1111/J.2047-2927.2013.00181.X
Article CAS PubMed Google Scholar
Siregar S, Adriansjah R, Sibarani J, Mustafa A (2020) Effect of intracorporeal human adipose-derived stem cells (hADSCs) on corpora cavernosa transforming growth factor β1 (TGFβ1) and collagen type I concentration in wistar rat priapism model. Res Rep Urol 12:21–27. https://doi.org/10.2147/RRU.S232303
Article CAS PubMed PubMed Central Google Scholar
Sanli O, Armagan A, Kandirali E et al (2004) TGF-beta1 neutralizing antibodies decrease the fibrotic effects of ischemic priapism. Int J Impot Res 16(6):492–497. https://doi.org/10.1038/SJ.IJIR.3901261
Article CAS PubMed Google Scholar
Agoston DV (2017) How to translate time? The temporal aspect of human and rodent biology. Front Neurol 17(8):92. https://doi.org/10.3389/fneur.2017.00092.PMID:28367138;PMCID:PMC5355425
Milenkovic U, Albersen M, Castiglione F (2019) The mechanisms and potential of stem cell therapy for penile fibrosis. Nat Rev Urol 16(2):79–97. https://doi.org/10.1038/S41585-018-0109-7
Quinlan DM, Nelson RJ, Partin AW, Mostwin JL, Walsh PC (1989) The rat as a model for the study of penile erection. J Urol 141(3):656–661. https://doi.org/10.1016/S0022-5347(17)40926-8
Article CAS PubMed Google Scholar
El-Bahnasawy MS, Dawood A, Farouk A (2002) Low-flow priapism: risk factors for erectile dysfunction. BJU Int 89(3):285–290. https://doi.org/10.1046/J.1464-4096.2001.01510.X
Article CAS PubMed Google Scholar
Muneer A, Cellek S, Dogan A, Kell PD, Ralph DJ, Minhas S (2005) Investigation of cavernosal smooth muscle dysfunction in low flow priapism using an in vitro model. Int J Impot Res 17(1):10–18. https://doi.org/10.1038/SJ.IJIR.3901231
Article CAS PubMed Google Scholar
Alnajjar HM, Muneer A (2022) Recent advances in understanding and treating priapism. Fac Rev 11:23. https://doi.org/10.12703/R/11-23
Article PubMed PubMed Central Google Scholar
Uluocak N, Atılgan D, Erdemir F et al (2010) An animal model of ischemic priapism and the effects of melatonin on antioxidant enzymes and oxidative injury parameters in rat penis. Int Urol Nephrol 42(4):889–895. https://doi.org/10.1007/S11255-010-9706-Y
Erdemir F, Firat F, Markoc F et al (2014) The effect of pentoxifylline on penile cavernosal tissues in ischemic priapism-induced rat model. Int Urol Nephrol 46(10):1961–1967. https://doi.org/10.1007/S11255-014-0769-Z
Article CAS PubMed Google Scholar
Karakeci A, Firdolas F, Ozan T, Unus I, Ogras MS, Orhan I (2013) Second pathways in the pathophysiology of ischemic priapism and treatment alternatives. Urology 82(3):625–629. https://doi.org/10.1016/J.UROLOGY.2013.06.029
Karagüzel E, Bayraktar C, Kutlu O et al (2016) The possible protective effects of dipyridamole on ischemic reperfusion injury of priapism. Int Braz J Urol 42(1):146–153. https://doi.org/10.1590/S1677-5538.IBJU.2015.0072
Article PubMed PubMed Central Google Scholar
Yilmaz Y, Taken K, Atar M, Ergün M, Söylemez H (2015) Protective effect of curcumin on priapism and ischemia-reperfusion injury in rats. Eur Rev Med Pharmacol Sci 19(23):4664–4670
Gao L, Wu C, Fu F et al (2018) Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism. J Cell Mol Med 22(3):2018–2022. https://doi.org/10.1111/JCMM.13411
Article CAS PubMed Google Scholar
Kolukcu E, Kilic S, Parlaktas BS et al (2019) The effects of oxytocin on penile tissues in experimental priapism model in rats. Int Urol Nephrol 51(2):231–238. https://doi.org/10.1007/S11255-018-2046-Z
Article CAS PubMed Google Scholar
Cinar O, Bolat MS, Erdem S et al (2020) The effect of an antifibrotic agent, pirfenidone, on penile erectile function in an experimental rat model of ischemic priapism. Int J Impot Res 32(2):232–238. https://doi.org/10.1038/S41443-019-0152-9
Article CAS PubMed Google Scholar
Zakrzewski W, Dobrzyński M, Szymonowicz M, Rybak Z (2019) Stem cells: past, present, and future. Stem Cell Res Ther 10(1):68. https://doi.org/10.1186/S13287-019-1165-5
Article CAS PubMed PubMed Central Google Scholar
Michler RE (2014) Stem cell therapy for heart failure. Cardiol Rev 22(3):105–116. https://doi.org/10.1097/CRD.0000000000000018
Comments (0)