Bai Q, Wang X, Mao X, Hu D. Aldo-keto reductase 1 member B1 (AKR1B1) inhibits retinal ganglion cell activity via activating NF-κB pathway and inducing mouse BV-2 microglia activation. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2020;36(12):1063–8.

PubMed  Google Scholar 

Balestri F, Moschini R, Mura U, Cappiello M, Del Corso A. In search of differential inhibitors of aldose reductase. Biomolecules. 2022;12(4):485. https://doi.org/10.3390/biom12040485.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bolinger MT, Antonetti DA. Moving past anti-VEGF: novel therapies for treating diabetic retinopathy. Int J Mol Sci. 2016;17(9):1498. https://doi.org/10.3390/ijms17091498.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Boyle EI, Weng S, Gollub J, Jin H, Botstein D, Cherry JM, Sherlock G. GO::TermFinder–open source software for accessing gene ontology information and finding significantly enriched gene ontology terms associated with a list of genes. Bioinformatics. 2004;20(18):3710–5. https://doi.org/10.1093/bioinformatics/bth456.

Article  CAS  PubMed  Google Scholar 

Chiva C, Olivella R, Borràs E, Espadas G, Pastor O, Solé A, Sabidó E. QCloud: a cloud-based quality control system for mass spectrometry-based proteomics laboratories. PLoS ONE. 2018;13:e0189209. https://doi.org/10.1371/journal.pone.0189209.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cook B, Lewis GP, Fisher SK, Adler R. Apoptotic photoreceptor degeneration in experimental retinal detachment. Invest Ophthalmol Vis Sci. 1995;36(6):990–6.

CAS  PubMed  Google Scholar 

Dănilă AI, Ghenciu LA, Stoicescu ER, Bolintineanu SL, Iacob R, Săndesc MA, Faur AC. Aldose reductase as a key target in the prevention and treatment of diabetic retinopathy: a comprehensive review. Biomedicines. 2024;12(4):747. https://doi.org/10.3390/biomedicines12040747.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. ChEMBL web services: streamlining access to drug discovery data and utilities. Nucleic Acids Res. 2015;43(W1):W612–20. https://doi.org/10.1093/nar/gkv352.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Donaghue KC, Margan SH, Chan AK, Holloway B, Silink M, Rangel T, Bennetts B. The association of aldose reductase gene (AKR1B1) polymorphisms with diabetic neuropathy in adolescents. Diabet Med. 2005;22(10):1315–20. https://doi.org/10.1111/j.1464-5491.2005.01631.x.

Article  CAS  PubMed  Google Scholar 

Dos Santos FM, Ciordia S, Mesquita J, de Sousa JPC, Paradela A, Tomaz CT, Passarinha LAP. Vitreous humor proteome: unraveling the molecular mechanisms underlying proliferative and neovascular vitreoretinal diseases. Cell Mol Life Sci. 2022;80(1):22. https://doi.org/10.1007/s00018-022-04670-y.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Endo S, Matsunaga T, Soda M, Tajima K, Zhao HT, El-Kabbani O, et al. Selective inhibition of the tumor marker AKR1B10 by antiinflammatory N-phenylanthranilic acids and glycyrrhetic acid. Biol Pharm Bull. 2010;33(5):886–90. https://doi.org/10.1248/bpb.33.886.

Article  CAS  PubMed  Google Scholar 

Galati S, Di Stefano M, Macchia M, Poli G, Tuccinardi T. MolBook UNIPI-create, manage, analyze, and share your chemical data for free. J Chem Inf Model. 2023;63(13):3977–82. https://doi.org/10.1021/acs.jcim.3c00278.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Geller SF, Lewis GP, Anderson DH, Fisher SK. Use of the MIB-1 antibody for detecting proliferating cells in the retina. Invest Ophthalmol Vis Sci. 1995;36(3):737–44.

CAS  PubMed  Google Scholar 

Haines NR, Manoharan N, Olson JL, D’Alessandro A, Reisz JA. Metabolomics analysis of human vitreous in diabetic retinopathy and rhegmatogenous retinal detachment. J Proteome Res. 2018;17(7):2421–7. https://doi.org/10.1021/acs.jproteome.8b00169.

Article  CAS  PubMed  Google Scholar 

Huang SP, Palla S, Ruzycki P, Varma RA, Harter T, Reddy GB, Petrash JM. Aldo-keto reductases in the eye. J Ophthalmol. 2010. https://doi.org/10.1155/2010/521204.

Article  PubMed  PubMed Central  Google Scholar 

Hughes CS, Moggridge S, Müller T, Sorensen PH, Morin GB, Krijgsveld J. Single-pot, solid-phase-enhanced sample preparation for proteomics experiments. Nat Protoc. 2019;14(1):68–85. https://doi.org/10.1038/s41596-018-0082-x.

Article  CAS  PubMed  Google Scholar 

Huo QY, Zhu MC, Yang WC, Wang YP, Chen S. 4D label-free proteomic analysis of vitreous from patients with rhegmatogenous retinal detachment. Int J Ophthalmol. 2023;16(4):523–31. https://doi.org/10.18240/ijo.2023.04.05.

Article  PubMed  PubMed Central  Google Scholar 

Idrees S, Sridhar J, Kuriyan AE. Proliferative vitreoretinopathy: a review. Int Ophthalmol Clin. 2019;59(1):221–40. https://doi.org/10.1097/IIO.0000000000000258.

Article  PubMed  PubMed Central  Google Scholar 

Ishikawa K, Akiyama M, Mori K, Nakama T, Notomi S, Nakao S, Kohno RI, Takeda A, Sonoda KH. Drainage retinotomy confers risk of epiretinal membrane formation after vitrectomy for rhegmatogenous retinal detachment repair. Am J Ophthalmol. 2022;234:20–7. https://doi.org/10.1016/j.ajo.2021.07.028.

Article  PubMed  Google Scholar 

Kanukollu VM, Agarwal P. Epiretinal membrane. Treasure Island (FL): StatPearls Publishing; 2024.

Google Scholar 

Kim HJ, Kim T, Hoffman NJ, Xiao D, James DE, Humphrey SJ, Yang P. PhosR enables processing and functional analysis of phosphoproteomic data. Cell Rep. 2021;34:108771. https://doi.org/10.1016/j.celrep.2021.108771.

Article  CAS  PubMed  Google Scholar 

Kustatscher G, Collins T, Gingras AC, Guo T, Hermjakob H, Ideker T, Lilley KS, Lundberg E, Marcotte EM, Ralser M, Rappsilber J. Understudied proteins: opportunities and challenges for functional proteomics. Nat Methods. 2022;19(7):774–9. https://doi.org/10.1038/s41592-022-01454-x.

Article  CAS  PubMed  Google Scholar 

Léveillard T, Sahel JA. Metabolic and redox signaling in the retina. Cell Mol Life Sci. 2017;74(20):3649–65. https://doi.org/10.1007/s00018-016-2318-7.

Article  CAS  PubMed  Google Scholar 

Li J, Lu Q, Lu P. Quantitative proteomics analysis of vitreous body from type 2 diabetic patients with proliferative diabetic retinopathy. BMC Ophthalmol. 2018;18(1):151. https://doi.org/10.1186/s12886-018-0821-3.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mishra C, Tripathy K. Retinal traction detachment. Treasure Island (FL): StatPearls Publishing; 2024.

Google Scholar 

Mitchell S, Siegel DH, Shieh JT, Stevenson DA, Grimmer JF, Lewis T, Metry D, Frieden I, Blei F, Kayserili H, Drolet BA, Bayrak-Toydemir P. Candidate locus analysis for PHACE syndrome. Am J Med Genet A. 2012 Jun; 158A(6): 1363–7. https://doi.org/10.1002/ajmg.a.35341. Epub 2012 Apr 27. Erratum in: Am J Med Genet A. 2022 Apr; 188(4): 1341. PMID: 22544659; PMCID: PMC3356486.

Mitry D, Charteris DG, Fleck BW, Campbell H, Singh J. The epidemiology of rhegmatogenous retinal detachment: geographical variation and clinical associations. Br J Ophthalmol. 2010;94(6):678–84. https://doi.org/10.1136/bjo.2009.157727.

Article  CAS  PubMed  Google Scholar 

Müller T, Kalxdorf M, Longuespée R, Kazdal DN, Stenzinger A, Krijgsveld J. Automated sample preparation with SP3 for low-input clinical proteomics. Mol Syst Biol. 2020;16(1):e9111. https://doi.org/10.15252/msb.20199111.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Murthy KR, Goel R, Subbannayya Y, Jacob HK, Murthy PR, Manda SS, Patil AH, Sharma R, Sahasrabuddhe NA, Parashar A, Nair BG, Krishna V, Prasad TK, Gowda H, Pandey H. Proteomic analysis of human vitreous humor. Clin Proteomics. 2014;11(1):29. https://doi.org/10.1186/1559-0275-11-29.

Article  CAS