Auguste YSS, Ferro A, Kahng JA, Xavier AM, Dixon JR, Vrudhula U, et al. Oligodendrocyte precursor cells engulf synapses during circuit remodeling in mice. Nat Neurosci. 2022;25:1273–8.
Article CAS PubMed PubMed Central Google Scholar
Akay LA, Effenberger AH, Tsai L-H. Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune function. Genes Dev. 2021;35:180–98.
Article CAS PubMed PubMed Central Google Scholar
Hirschfeld LR, Risacher SL, Nho K, Saykin AJ. Myelin repair in Alzheimer’s disease: a review of biological pathways and potential therapeutics. Transl Neurodegener. 2022;11:47.
Article CAS PubMed PubMed Central Google Scholar
Fields RD, Bukalo O. Myelin makes memories. Nat Neurosci. 2020;23:469–70.
Article CAS PubMed PubMed Central Google Scholar
Philips T, Rothstein JD. Oligodendroglia: metabolic supporters of neurons. J Clin Invest. 2017;127:3271–80.
Article PubMed PubMed Central Google Scholar
Marangon D, Boccazzi M, Lecca D, Fumagalli M. Regulation of oligodendrocyte functions: targeting lipid metabolism and extracellular matrix for myelin repair. J Clin Med. 2020;9:470.
Article CAS PubMed PubMed Central Google Scholar
Peferoen L, Kipp M, Valk P, Noort JM, Amor S. Oligodendrocyte-microglia cross-talk in the central nervous system. Immunology. 2014;141:302–13.
Article CAS PubMed PubMed Central Google Scholar
Johnson ECB, Bian S, Haque RU, Carter EK, Watson CM, Gordon BA, et al. Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease. Nat Med. 2023;29:1979–88.
Article CAS PubMed PubMed Central Google Scholar
Schuster KH, Zalon AJ, Zhang H, DiFranco DM, Stec NR, Haque Z, et al. Impaired oligodendrocyte maturation is an early feature in SCA3 Disease Pathogenesis. J Neurosci. 2022;42:1604–17.
Article CAS PubMed PubMed Central Google Scholar
Blanchard JW, Akay LA, Davila-Velderrain J, von Maydell D, Mathys H, Davidson SM, et al. APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes. Nature. 2022;611:769–79.
Article CAS PubMed PubMed Central Google Scholar
Schlett JS, Mettang M, Skaf A, Schweizer P, Errerd A, Mulugeta EA, et al. NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss. Mol Neurodegener. 2023;18:24.
Article CAS PubMed PubMed Central Google Scholar
Gazestani V, Kamath T, Nadaf NM, Dougalis A, Burris SJ, Rooney B, et al. Early Alzheimer’s disease pathology in human cortex involves transient cell states. Cell. 2023;186:4438–e445323.
Article CAS PubMed PubMed Central Google Scholar
Sasmita AO, Depp C, Nazarenko T, Sun T, Siems SB, Ong EC, et al. Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice. Nat Neurosci. 2024;27:1668–74.
Article CAS PubMed PubMed Central Google Scholar
Akihiro I, Pathoulas JA, Omar OM, Fathy, Ge, Yingying, Yao, Annie Y, Pantalena, Tressa et al. Contribution of amyloid deposition from oligodendrocytes in a mouse model of Alzheimer’s disease. Mol Neurodegener. 2024; https://doi.org/10.1186/s13024-024-00759-z.
Gabitto MI, Travaglini KJ, Rachleff VM et al. Integrated multimodal cell atlas of Alzheimer’s disease. Nat Neurosci. 2024; https://doi.org/10.1038/s41593-024-01774-5.
Parrilla GE, Gupta V, Wall RV, Salkar A, Basavarajappa D, Mirzaei M, et al. The role of myelin in neurodegeneration: implications for drug targets and neuroprotection strategies. Rev Neurosci. 2024;35:271–92.
Comments (0)