Baxi SS, Pinheiro LC, Pati SM, Pfister DG, Oeffinger KC, Elkin EB (2014) Causes of death in long term survivors of head and neck cancer. Cancer 120:1507–1513

Article  PubMed  Google Scholar 

Tsai CJ, Hofstede TM, Sturgis EM, Garden AS, Lindberg ME, Wei Q, Tucker SL, Dong L (2013) Osteoradionecrosis and radiation dose to the mandible in patients with oropharyngeal cancer. Int J Radiat Oncol Biol Phys 85(2):415–420

Article  PubMed  Google Scholar 

Aarup-Kristensen S, Hansen CR, Fornber L, Brink C, Eriksen JG, Johansen J Osteoradionecrosis of the mandible after radiotherapy for head and neck cancer: risk factors and dose-volume correlations. Acta Oncol. https://doi.org/10.1080/0284186X.2019.1643037

Caparrotti F, Huang SH, Lu L, Bratman SV, Ringash J, Bayley A, Cho J, Giuliani M, Kim J, Waldron J, Hansen A, Tong L, Xu W, O’Sullivan B, Wood R, Goldstein D, Hope A (2017) Osteoradionecrosis of the mandible in patients with oropharyngeal carcinoma treated with intensity-modulated radiotherapy. Cancer 123(19):3691–3700. https://doi.org/10.1002/cncr.30803

Article  PubMed  Google Scholar 

Kovarik JP, Voborna I, Barclay S, Iqbal MS, Cunnell M, Kelly C, Willis N, Kennedy M, Kovarik J (2022) Osteoradionecrosis after treatment of head and neck cancer: a comprehensive analysis of risk factors with a particular focus on role of dental extractions. Br J Oral Maxillofac Surg 60(2):168–173. https://doi.org/10.1016/j.bjoms.2021.03.009

Article  CAS  PubMed  Google Scholar 

Notani K, Yamazaki Y, Kitada H, Sakakibara N, Fukuda H, Omori K, Nakamura M (2003) Management of mandibular osteoradionecrosis corresponding to the severity of osteoradionecrosis and the method of radiotherapy. Head Neck 25(3):181–186. https://doi.org/10.1002/hed.10171

Article  PubMed  Google Scholar 

Kubota H, Miyawaki D, Mukumoto N et al (2021) Risk factors for osteoradionecrosis of the jaw in patients with head and neck squamous cell carcinoma. Radiat Oncol. https://doi.org/10.1186/s13014-020-01701-5

Article  PubMed  PubMed Central  Google Scholar 

Owosho AA, Tsai CJ, Lee RS, Freymiller H, Kadempour A, Varthis S et al (2017) The prevalence and risk factors associated with osteoradionecrosis of the jaw in oral and oropharyngeal cancer patients treated ith intensity-modulated radiation therapy: the memorial Sloan Kettering cancer center experience. Oral Oncol 64:44–51. https://doi.org/10.1016/j.oraloncology.2016.11.015

Article  PubMed  Google Scholar 

Reuther T, Schuster T, Mende U, Kübler A (2003) Osteoradionecrosis of the jaws as a side effect of radiotherapy of head and neck tumour patients—a report of a thirty year retrospective review. Int J Oral Maxillofac Surg 32(3):289–295. https://doi.org/10.1054/ijom.2002.0332

Article  CAS  PubMed  Google Scholar 

Moon DH, Moon SH, Wang K, Weissler MC, Hackman TG, Zanation AM et al (2017) Incidence of, and risk factors for, mandibular osteoradionecrosis in patients with oral cavity and oropharynx cancers. Oral Oncol 72:98–103. https://doi.org/10.1016/j.oraloncology.2017.07.014

Article  PubMed  Google Scholar 

Kabir R, Durand R, Roberge D, Dufresne E, Nguyen-Tân PF (2022) Incidence of osteoradionecrosis of the jaws: a retrospective study of 620 patients with head and neck cancer. Gen Dent 70(4):72–77

PubMed  Google Scholar 

Kuhnt T, Stang A, Wienke A, Vordermark D, Schweyen R, Hey J (2016) Potential risk factors for jaw osteoradionecrosis after radiotherapy for head and neck cancer. Radiat Oncol 11:101. https://doi.org/10.1186/s13014-016-0679-6

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chang DT, Sandow PR, Morris CG, Hollander R, Scarborough L, Amdur RJ, Mendenhall WM (2007) Do pre-irradiation dental extractions reduce the risk of osteoradionecrosis of the mandible? Head Neck 29(6):528–536. https://doi.org/10.1002/hed.20538

Article  PubMed  Google Scholar 

van Dijk LV, Abusaif AA, Rigert J, Naser MA, Hutcheson KA, Lai SY, Fuller CD, Mohamed ASR, MD Anderson Symptom Working Group. (2021) Normal tissue complication probability (NTCP) prediction model for osteoradionecrosis of the mandible in patients with head and neck cancer after radiation therapy: large-scale observational cohort. Int J Radiat Oncol Biol Phys 111(2):549–558. https://doi.org/10.1016/j.ijrobp.2021.04.042

Article  PubMed  PubMed Central  Google Scholar 

Möring MM, Mast H, Wolvius EB, Verduijn GM, Petit SF, Sijtsema ND, Jonker BP, Nout RA, Heemsbergen WD (2022) Osteoradionecrosis after postoperative radiotherapy for oral cavity cancer: a retrospective cohort study. Oral Oncol 133:106056. https://doi.org/10.1016/j.oraloncology.2022.106056

Article  PubMed  Google Scholar 

Lee CT, Litwin S, Yao CMKL, Liu JC, Ridge JA, Galloway TJ (2022) Osteoradionecrosis rate in oropharynx cancer treated with dose volume histogram based constraints. Radiother Oncol 176:215–221. https://doi.org/10.1016/j.radonc.2022.10.011

Article  PubMed  Google Scholar 

Studer G, Bredell M, Studer S, Huber G, Glanzmann C (2016) Risk profile for osteoradionecrosis of the mandible in the IMRT era. Strahlenther Onkol 192(1):32–39. https://doi.org/10.1007/s00066-015-0875-6

Article  PubMed  Google Scholar 

Kovarik JP, Voborna I, Barclay S, Nicol A, Kelly C, Kovarik PD, Iqbal MS, Kovarik J (2021) Dental loss after radiotherapy for head and neck cancer. Br Dent J 231(8):473–478. https://doi.org/10.1038/s41415-021-3536-4

Article  PubMed  Google Scholar 

Vigarios E, Epstein JB, Sibaud V (2017) Oral mucosal changes induced by anticancer targeted therapies and immune checkpoint inhibitors. Support Care Cancer 25:1713–1739

Article  PubMed  Google Scholar 

Beumer J III, Harrison R, Sanders B, Kurrasch M (1983) Postradiation dental extractions: a review of the literature and a report of 72 episodes. Head Neck 6:581–586. https://doi.org/10.1002/hed.2890060107

Article  Google Scholar 

Thorn JJ, Hansen HS, Specht L, Bastholt L (2000) Osteoradionecrosis of the jaws: clinical characteristics and relation to the field of irradiation. J Oral Maxillofac Surg 58(10):1088–1093. https://doi.org/10.1053/joms.2000.9562 (discussion 1093–5)

Article  CAS  PubMed  Google Scholar 

Marx RE (1983) Osteoradionecrosis: a new concept of its pathophysiology. J Oral Maxillofac Surg 41(5):283–288. https://doi.org/10.1016/0278-2391(83)90294-x

Article  CAS  PubMed  Google Scholar 

Kovarik PDE, Patil R, Cvek J, Kelly C, Jackson M, Mackenzie L, West N, Willis N, Kovarik JP, Banks R, Kennedy M, Adams J, Iqbal MS (2023) Extra-mandibular osteoradionecrosis after the treatment of head and neck cancer. Clin Oncol 35(9):e498–e505. https://doi.org/10.1016/j.clon.2023.06.013

Article  CAS  Google Scholar