Hochrainer K, Yang W. Stroke proteomics: from discovery to diagnostic and therapeutic applications. Circ Res. 2022;130(8):1145–66.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Henderson SJ, Weitz JI, Kim PY. Fibrinolysis: strategies to enhance the treatment of acute ischemic stroke. J Thromb Haemost. 2018;16(10):1932–40.

Article  CAS  PubMed  Google Scholar 

Grotta JC, Yamal JM, Parker SA, Rajan SS, Gonzales NR, Jones WJ, Alexandrov AW, Navi BB, Nour M, Spokoyny I, Mackey J, Persse D, Jacob AP, Wang M, Singh N, Alexandrov AV, Fink ME, Saver JL, English J, Barazangi N, Bratina PL, Gonzalez M, Schimpf BD, Ackerson K, Sherman C, Lerario M, Mir S, Im J, Willey JZ, Chiu D, Eisshofer M, Miller J, Ornelas D, Rhudy JP, Brown KM, Villareal BM, Gausche-Hill M, Bosson N, Gilbert G, Collins SQ, Silnes K, Volpi J, Misra V, McCarthy J, Flanagan T, Rao CPV, Kass JS, Griffin L, Rangel-Gutierrez N, Lechuga E, Stephenson J, Phan K, Sanders Y, Noser EA, Bowry R. Prospective, multicenter, controlled trial of mobile stroke units. N Engl J Med. 2021;385(11):971–81.

Article  PubMed  Google Scholar 

Tsivgoulis G, Katsanos AH, Sandset EC, Turc G, Nguyen TN, Bivard A, Fischer U, Khatri P. Thrombolysis for acute ischaemic stroke: current status and future perspectives. Lancet Neurol. 2023;22(5):418–29.

Article  CAS  PubMed  Google Scholar 

Goncalves A, Su EJ, Muthusamy A, Zeitelhofer M, Torrente D, Nilsson I, Protzmann J, Fredriksson L, Eriksson U, Antonetti DA, Lawrence DA. Thrombolytic tPA-induced hemorrhagic transformation of ischemic stroke is mediated by PKCbeta phosphorylation of occludin. Blood. 2022;140(4):388–400.

CAS  PubMed  PubMed Central  Google Scholar 

Ledford H. How stem cells make a human brain. Nature. 2023;615(7954):776–7.

Article  CAS  PubMed  Google Scholar 

Jiang XC, Xiang JJ, Wu HH, Zhang TY, Zhang DP, Xu QH, Huang XL, Kong XL, Sun JH, Hu YL, Li K, Tabata Y, Shen YQ, Gao JQ. Neural stem cells transfected with reactive oxygen species-responsive polyplexes for effective treatment of ischemic stroke. Adv Mater. 2019;31(10): e1807591.

Article  PubMed  Google Scholar 

Sun J, Huang Y, Gong J, Wang J, Fan Y, Cai J, Wang Y, Qiu Y, Wei Y, Xiong C, Chen J, Wang B, Ma Y, Huang L, Chen X, Zheng S, Huang W, Ke Q, Wang T, Li X, Zhang W, Xiang AP, Li W. Transplantation of hPSC-derived pericyte-like cells promotes functional recovery in ischemic stroke mice. Nat Commun. 2020;11(1):5196.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Denoth-Lippuner A, Jessberger S. Formation and integration of new neurons in the adult hippocampus. Nat Rev Neurosci. 2021;22(4):223–36.

Article  CAS  PubMed  Google Scholar 

Stenudd M, Sabelstrom H, Frisen J. Role of endogenous neural stem cells in spinal cord injury and repair. JAMA Neurol. 2015;72(2):235–7.

Article  PubMed  Google Scholar 

Xiong M, Tao Y, Gao Q, Feng B, Yan W, Zhou Y, Kotsonis TA, Yuan T, You Z, Wu Z, Xi J, Haberman A, Graham J, Block J, Zhou W, Chen Y, Zhang SC. Human stem cell-derived neurons repair circuits and restore neural function. Cell Stem Cell. 2021;28(1):112-26 e6.

Article  CAS  PubMed  Google Scholar 

Marqués-Torrejón M, Williams CAC, Southgate B, Alfazema N, Clements MP, Garcia-Diaz C, Blin C, Arranz-Emparan N, Fraser J, Gammoh N, Parrinello S, Pollard SM. LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells. Nat Commun. 2021;12(1):2594.

Article  PubMed  PubMed Central  Google Scholar 

Adusumilli VS, Walker TL, Overall RW, Klatt GM, Zeidan SA, Zocher S, Kirova DG, Ntitsias K, Fischer TJ, Sykes AM, Reinhardt S, Dahl A, Mansfeld J, Rünker AE, Kempermann G. ROS dynamics delineate functional states of hippocampal neural stem cells and link to their activity-dependent exit from quiescence. Cell Stem Cell. 2021;28(2):300-14.e6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Roth JG, Huang MS, Li TL, Feig VR, Jiang Y, Cui B, Greely HT, Bao Z, Pasca SP, Heilshorn SC. Advancing models of neural development with biomaterials. Nat Rev Neurosci. 2021;22(10):593–615.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sugita S, Mandai M, Kamao H, Takahashi M. Immunological aspects of RPE cell transplantation. Prog Retin Eye Res. 2021;84:100950.

Article  CAS  PubMed  Google Scholar 

Wang ZB, Wang ZT, Sun Y, Tan L, Yu JT. The future of stem cell therapies of Alzheimer’s disease. Ageing Res Rev. 2022;80:101655.

Article  CAS  PubMed  Google Scholar 

Lu X, Sun C, Chen L, Feng Z, Gao H, Hu S, Dong M, Wang J, Zhou W, Ren N, Zhou H, Liu H. Stemness maintenance and massproduction of neural stem cells on poly L-lactic acid nanofibrous membrane based on piezoelectriceffect. Small. 2022;18(13): e2107236.

Article  PubMed  Google Scholar 

Allen DE, Donohue KC, Cadwell CR, Shin D, Keefe MG, Sohal VS, Nowakowski TJ. Fate mapping of neural stem cell niches reveals distinct origins of human cortical astrocytes. Science. 2022;376(6600):1441–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Karzbrun E, Khankhel AH, Megale HC, Glasauer SMK, Wyle Y, Britton G, Warmflash A, Kosik KS, Siggia ED, Shraiman BI, Streichan SJ. Human neural tube morphogenesis in vitro by geometric constraints. Nature. 2021;599(7884):268–72.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Watanabe Y, Miyasaka KY, Kubo A, Kida YS, Nakagawa O, Hirate Y, Sasaki H, Ogura T. Notch and hippo signaling converge on strawberry notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm. Sci Rep. 2017;7:46135.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shen C, Yu J, Zhang X, Liu CC, Guo YS, Zhu JW, Zhang K, Yu Y, Gao TT, Yang SM, Li H, Zheng B, Huang XY. Strawberry Notch 1 (SBNO1) promotes proliferation of spermatogonial stem cells via the noncanonical Wnt pathway in mice. Asian J Androl. 2019;21(4):345–50.

Article  CAS  PubMed  Google Scholar 

Takano A, Zochi R, Hibi M, Terashima T, Katsuyama Y. Expression of strawberry notch family genes during zebrafish embryogenesis. Dev Dyn. 2010;239(6):1789–96.

Article  CAS  PubMed  Google Scholar 

Bulayeva K, Lesch KP, Bulayev O, Walsh C, Glatt S, Gurgenova F, Omarova J, Berdichevets I, Thompson PM. Genomic structural variants are linked with intellectual disability. J Neural Transm. 2015;122(9):1289–301.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cetin A, Komai S, Eliava M, Seeburg PH, Osten P. Stereotaxic gene delivery in the rodent brain. Nat Protoc. 2006;1(6):3166–73.

Article  CAS  PubMed  Google Scholar 

Panciera T, Azzolin L, Fujimura A, Di Biagio D, Frasson C, Bresolin S, Soligo S, Basso G, Bicciato S, Rosato A, Cordenonsi M, Piccolo S. Induction of expandable tissue-specific stem/progenitor cells through transient expression of YAP/TAZ. Cell Stem Cell. 2016;19(6):725–37.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hung CH, Young TH. Differences in the effect on neural stem cells of fetal bovine serum in substrate-coated and soluble form. Biomaterials. 2006;27(35):5901–8.

Article  CAS  PubMed  Google Scholar 

Dinsmore JH, Solomon F. Inhibition of MAP2 expression affects both morphological and cell division phenotypes of neuronal differentiation. Cell. 1991;64(4):817–26.

Article  CAS  PubMed  Google Scholar 

Sofroniew MV. Stem-cell-derived astrocytes divulge secrets of mutant GFAP. Cell Stem Cell. 2018;23(5):630–1.

Article  CAS  PubMed