Canadian Institute for Health Information. Care in Canadian ICUs; 2016. Available from URL: https://secure.cihi.ca/free_products/ICU_Report_EN.pdf (accessed April 2024).

Desai SV, Law TJ, Needham DM. Long-term complications of critical care. Crit Care Med 2011; 39: 371–9. https://doi.org/10.1097/ccm.0b013e3181fd66e5

Article  PubMed  Google Scholar 

Herridge MS, Azoulay É. Outcomes after critical illness. N Engl J Med 2023; 388: 913–24. https://doi.org/10.1056/nejmra2104669

Article  CAS  PubMed  Google Scholar 

Schweickert WD, Pohlman MC, Pohlman AS, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet 2009; 373: 1874–82. https://doi.org/10.1016/s0140-6736(09)60658-9

Article  PubMed  PubMed Central  Google Scholar 

Burtin C, Clerckx B, Robbeets C, et al. Early exercise in critically ill patients enhances short-term functional recovery. Crit Care Med 2009; 37: 2499–505. https://doi.org/10.1097/ccm.0b013e3181a38937

Article  PubMed  Google Scholar 

Zhang F, Xia Q, Zhang L, Wang H, Bai Y, Wu W. A bibliometric and visualized analysis of early mobilization in intensive care unit from 2000 to 2021. Front Neurol 2022; 13: 848545. https://doi.org/10.3389/fneur.2022.848545

Article  PubMed  PubMed Central  Google Scholar 

Castro-Avila AC, Serón P, Fan E, Gaete M, Mickan S. Effect of early rehabilitation during intensive care unit stay on functional status: systematic review and meta-analysis. PLoS One 2015; 10: e0130722. https://doi.org/10.1371/journal.pone.0130722

Article  CAS  PubMed  PubMed Central  Google Scholar 

Menges D, Seiler B, Tomonaga Y, Schwenkglenks M, Puhan MA, Yebyo HG. Systematic early versus late mobilization or standard early mobilization in mechanically ventilated adult ICU patients: systematic review and meta-analysis. Crit Care 2021; 25: 16. https://doi.org/10.1186/s13054-020-03446-9

Article  PubMed  PubMed Central  Google Scholar 

Tipping CJ, Harrold M, Holland A, Romero L, Nisbet T, Hodgson CL. The effects of active mobilisation and rehabilitation in ICU on mortality and function: a systematic review. Intensive Care Med 2017; 43: 171–83. https://doi.org/10.1007/s00134-016-4612-0

Article  PubMed  Google Scholar 

Berney SC, Harrold M, Webb SA, et al. Intensive care unit mobility practices in Australia and New Zealand: a point prevalence study. Crit Care Resusc 2013; 15: 260–5. https://doi.org/10.1016/S1441-2772(23)01424-2

Article  PubMed  Google Scholar 

Nydahl P, Ruhl AP, Bartoszek G, et al. Early mobilization of mechanically ventilated patients: a 1-day point-prevalence study in Germany. Crit Care Med 2014; 42: 1178–86. https://doi.org/10.1097/ccm.0000000000000149

Article  PubMed  Google Scholar 

Jolley SE, Moss M, Needham DM, et al. Point prevalence study of mobilization practices for acute respiratory failure patients in the United States. Crit Care Med 2017; 45: 205–15. https://doi.org/10.1097/ccm.0000000000002058

Article  PubMed  PubMed Central  Google Scholar 

Sibilla A, Nydahl P, Greco N, et al. Mobilization of mechanically ventilated patients in Switzerland. J Intensive Care Med 2020; 35: 55–62. https://doi.org/10.1177/0885066617728486

Article  PubMed  Google Scholar 

Fontela PC, Lisboa TC, Forgiarini-Júnior LA, Friedman G. Early mobilization practices of mechanically ventilated patients: a 1-day point-prevalence study in southern Brazil. Clinics (Sao Paulo) 2018; 73: e241. https://doi.org/10.6061/clinics/2018/e241

Article  PubMed  Google Scholar 

Skinner EH, Haines KJ, Berney S, Warrillow S, Harrold M, Denehy L. Usual care physiotherapy during acute hospitalization in subjects admitted to the ICU: an observational cohort study. Respir Care 2015; 60: 1476–85. https://doi.org/10.4187/respcare.04064

Article  PubMed  Google Scholar 

Tadyanemhandu C, Manie S. Profile of patients and physiotherapy patterns in intensive care units in public hospitals in Zimbabwe: a descriptive cross-sectional study. BMC Anesthesiol 2015; 15: 136. https://doi.org/10.1186/s12871-015-0120-y

Article  PubMed  PubMed Central  Google Scholar 

Hodgson C, Bellomo R, Berney S, et al. Early mobilization and recovery in mechanically ventilated patients in the ICU: a bi-national, multi-centre, prospective cohort study. Crit Care. 2015;19(1):81. https://doi.org/10.1186/s13054-015-0765-4

Article  PubMed  Google Scholar 

Hodgson CL, Bailey M, Bellomo R, et al. A binational multicenter pilot feasibility randomized controlled trial of early goal-directed mobilization in the ICU. Crit Care Med 2016; 44: 1145–52. https://doi.org/10.1097/ccm.0000000000001643

Article  PubMed  Google Scholar 

Wright SE, Thomas K, Watson G, et al. Intensive versus standard physical rehabilitation therapy in the critically ill (EPICC): a multicentre, parallel-group, randomised controlled trial. Thorax 2018; 73: 213–21. https://doi.org/10.1136/thoraxjnl-2016-209858

Article  PubMed  Google Scholar 

O’Grady HK, Reid JC, Farley C, et al. Comparator groups in ICU-based studies of physical rehabilitation: a scoping review of 125 studies. Crit Care Explor 2023; 5: e0917. https://doi.org/10.1097/cce.0000000000000917

Article  PubMed  PubMed Central  Google Scholar 

Hodgson CL, Bailey M, Bellomo R, et al. Early active mobilization during mechanical ventilation in the ICU. N Engl J Med 2022; 387: 1747–58. https://doi.org/10.1056/nejmoa2209083

Article  PubMed  Google Scholar 

Paton M, Chan S, Tipping CJ, et al. The effect of mobilization at 6 months after critical illness—meta-analysis. NEJM Evid 2023; 2: EVIDoa2200234. https://doi.org/10.1056/evidoa2200234

Bakhru RN, McWilliams DJ, Wiebe DJ, Spuhler VJ, Schweickert WD. Intensive care unit structure variation and implications for early mobilization practices. An international survey. Ann Am Thorac Soc 2016; 13: 1527–37. https://doi.org/10.1513/annalsats.201601-078oc

Article  PubMed  PubMed Central  Google Scholar 

Devlin JW, Skrobik Y, Gélinas C, et al. Clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU. Crit Care Med 2018; 46: e825–73. https://doi.org/10.1097/ccm.0000000000003299

Article  PubMed  Google Scholar 

Kho ME, Molloy AJ, Clarke FJ, et al. Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients. BMJ Open Respir Res 2019; 6: e000383. https://doi.org/10.1136/bmjresp-2018-000383

Article  PubMed  PubMed Central  Google Scholar 

Elm E von, Altman DG, Egger M, et al. Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. BMJ 2007; 335: 806–8. https://doi.org/10.1136/bmj.39335.541782.ad

Article  Google Scholar 

Kho ME, Molloy AJ, Clarke F, et al. CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients. BMJ Open 2016; 6: e011659. https://doi.org/10.1136/bmjopen-2016-011659

Article  PubMed  PubMed Central  Google Scholar 

Hodgson C, Needham D, Haines K, et al. Feasibility and inter-rater reliability of the ICU Mobility Scale. Heart Lung 2014; 43: 19–24. https://doi.org/10.1016/j.hrtlng.2013.11.003

Article  PubMed  Google Scholar 

Nydahl P, Sricharoenchai T, Chandra S, et al. Safety of patient mobilization and rehabilitation in the intensive care unit. Systematic review with meta-analysis. Ann Am Thorac Soc 2017; 14: 766–77. https://doi.org/10.1513/annalsats.201611-843sr

Article  PubMed  Google Scholar 

Stiller K. Physiotherapy in intensive care: an updated systematic review. Chest 2013; 144: 825–47. https://doi.org/10.1378/chest.12-2930

Article  PubMed  Google Scholar 

Pozuelo-Carrascosa DP, Torres-Costoso A, Alvarez-Bueno C, Cavero-Redondo I, López Muñoz P, Martínez-Vizcaíno V. Multimodality respiratory physiotherapy reduces mortality but may not prevent ventilator-associated pneumonia or reduce length of stay in the intensive care unit: a systematic review. J Physiother 2018; 64: 222–8. https://doi.org/10.1016/j.jphys.2018.08.005

Article  PubMed