Cerebellum and basal ganglia connectivity in isolated REM sleep behaviour disorder and Parkinson’s disease: an exploratory study

Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annual Review of Neuroscience, 9, 357–381. https://doi.org/10.1146/annurev.ne.09.030186.002041

Article  CAS  PubMed  Google Scholar 

American Academy of Sleep Medicine. (2014). The International classification of Sleep disorders (3rd ed.). American Academy of Sleep Medicine.

Bostan, A. C., & Strick, P. L. (2010). The cerebellum and basal ganglia are interconnected. Neuropsychology Review, 20, 261–270. https://doi.org/10.1007/s11065-010-9143-9

Article  PubMed  PubMed Central  Google Scholar 

Boucetta, S., Salimi, A., Dadar, M., Jones, B. E., Collins, D. L., & Dang-Vi, T. T. (2016). Structural brain alterations associated with rapid eye movement sleep behavior disorder in Parkinson’s disease. Scientific Reports, 6, 26782. https://doi.org/10.1038/srep26782

Article  CAS  PubMed  PubMed Central  Google Scholar 

Byun, J-I., Kim, H-W., Kang, H., Cha, K. S., Sunwoo, J-S., Shin, J-W., Moon, J., Lee, S-T., Jung, K-H., Chu, K., Kim, M., Shin, W. C., Lee, D. S., Schenck, C. H., Lee, S. K., & Jung, K-Y. (2020). Altered resting-state thalamo-occipital functional connectivity is associated with cognition in isolated rapid eye movement sleep behavior disorder. Sleep Medicine, 69, 198–203. https://doi.org/10.1016/j.sleep.2020.01.010

Article  PubMed  Google Scholar 

Chen, Z., He, C., Zhang, P., Cai, X., Huang, W., Chen, X., Xu, M., Wang, L., & Zhang, Y. (2023). Abnormal cerebellum connectivity patterns related to motor subtypes of Parkinson’s disease. Journal of Neural Transmission, 130, 549–560. https://doi.org/10.1007/s00702-023-02606-9

Article  PubMed  PubMed Central  Google Scholar 

Choi, E., Han, J. W., Suh, S. W., Bae, J. B., Han, J. H., Lee, S., Kim, S. E., & Kim, K. W. (2022). Altered resting state brain metabolic connectivity in dementia with Lewy bodies. Frontiers in Neurology, 13, 847935. https://doi.org/10.3389/fneur.2022.847935

Article  PubMed  PubMed Central  Google Scholar 

Dayan, E., & Browner, N. (2017). Alterations in striato-thalamo-pallidal intrinsic functional connectivity as a prodrome of Parkinson’s disease. NeuroImage: Clinical, 16, 313–318. https://doi.org/10.1016/j.nicl.2017.08.003

Article  PubMed  Google Scholar 

Dirkx, M. F., den Ouden, H. E. M., Aarts, E., Timmer, M. H. M., Bloem, B. R., Toni, I., & Helmich, R. C. (2017). Dopamine controls Parkinson’s tremor by inhibiting the cerebellar thalamus. Brain, 140(3), 721–734. https://doi.org/10.1093/brain/aww331

Article  PubMed  Google Scholar 

Ellmore, T. M., Castriotta, R. J., Hendley, K. L., Aalbers, B. M., Furr-Stimming, E., Hood, A. J., Suescun, J., Hendley, M. R. B., & Schiess, R. T. MC (2013). Altered nigrostriatal and nigrocortical functional connectivity in rapid eye movement sleep behavior disorder. Sleep, 36(12), 1885–1892. https://doi.org/10.5665/sleep.3222

Article  PubMed  PubMed Central  Google Scholar 

Fedorova, T. D., Knudsen, K., Andersen, K. B., Horsager, J., Skjærbæk, C., Beier, C. P., Sommerauer, M., Svendsen, K. B., Otto, M., & Borghammer, P. (2022). Imaging progressive peripheral and central dysfunction in isolated REM sleep behaviour disorder after 3 years of follow-up. Parkinsonism & Related Disorders, 101, 99–104. https://doi.org/10.1016/j.parkreldis.2022.07.005

Article  Google Scholar 

García-Gomar, M. G., Videnovic, A., Singh, K., Stauder, M., Lewis, L. D., Wald, L. L., Rosen, B. R., & Bianciardi, M. (2022). Disruption of brainstem structural connectivity in REM sleep behavior disorder using 7 tesla magnetic resonance imaging. Movement Disorders, 37(4), 847–853. https://doi.org/10.1002/mds.28895

Article  PubMed  Google Scholar 

Goetz, C. G., Tilley, B. C., Shaftman, S. R., Stebbins, G. T., Fahn, S., Martinez-Martin, P., Poewe, W., Sampaio, C., Stern, M. B., Dodel, R., Dubois, B., Holloway, R., Jankovic, J., Kulisevsky, J., Lang, A. E., Lees, A., Leurgans, S., LeWitt, P. A., Nyenhuis, D., Olanow, C. W., Rascol, O., Schrag, A., Teresi, J. A., van Hilten, J. J., LaPelle, N., & Force (2008). MDSURT Movement Disorder Society sponsored revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results. Mov Disord 23 (15):2129–2170. https://doi.org/10.1002/mds.22340

Guo, T., Guan, X., Zeng, Q., Xuan, M., Gu, Q., Huang, P., Xu, X., & Zhang, M. (2018). Alterations of brain structural network in Parkinson’s disease with and without rapid eye movement sleep behavior disorder. Frontiers in Neurology, 9, 334. https://doi.org/10.3389/fneur.2018.00334

Article  PubMed  PubMed Central  Google Scholar 

Habas, C. M., & Cabaraux, M., P (2019). The cerebellar thalamus. The Cerebellum, 18, 635–648. https://doi.org/10.1007/s12311-019-01019-3

Article  PubMed  Google Scholar 

Horsager, J., Andersen, K. B., Knudsen, K., Skjærbæk, C., Fedorova, T. D., Okkels, N., Schaeffer, E., Bonkat, S. K., Geday, J., Otto, M., Sommerauer, M., Danielsen, E. H., Bech, E., Kraft, J., Munk, O. L., Hansen, S. D., Pavese, N., Göder, R., Brooks, D. J., Berg, D., & Borghammer, P. (2020). Brain-first versus body-first Parkinson’s disease: A multimodal imaging case-control study. Brain, 143(10), 3077–3088. https://doi.org/10.1093/brain/awaa238

Article  PubMed  Google Scholar 

Hou, Y., Ou, R., Yang, J., Song, W., Gong, Q., & Shang, H. (2018). Patterns of striatal and cerebellar functional connectivity in early-stage drug-naïve patients with Parkinson’s disease subtypes. Neuroradiology, 60, 1323–1333. https://doi.org/10.1007/s00234-018-2101-6

Article  PubMed  Google Scholar 

Hu, M. T. (2020). REM sleep behavior disorder (RBD). Neurobiology of Disease, 143, 104996. https://doi.org/10.1016/j.nbd.2020.104996

Article  CAS  PubMed  Google Scholar 

Ji, J. L., Spronk, M., Kulkarni, K., Repovš, G., Anticevic, A., & Cole, M. W. (2019). Mapping the human brain’s cortical-subcortical functional network organization. Neuroimage, 185, 35–57. https://doi.org/10.1016/j.neuroimage.2018.10.006

Article  PubMed  Google Scholar 

Kamps, S., van den Heuvel, O. A., van der Werf, Y. D., Berendse, H. W., Weintraub, D., & Vriend, C. (2019). Smaller subcortical volume in Parkinson patients with rapid eye movement sleep behavior disorder. Brain Imaging Behav, 13(5), 1352–1360. https://doi.org/10.1007/s11682-018-9939-4

Article  PubMed  Google Scholar 

Kawabata, K., Watanabe, H., Bagarinao, E., Ohdake, R., Hara, K., Ogura, A., Masuda, M., Kato, T., Tsuboi, T., Maesawa, S., Katsuno, M., & Sobue, G. (2020). Cerebello-basal ganglia connectivity fingerprints related to motor/cognitive performance in Parkinson’s disease. Parkinsonism & Related Disorders, 80, 21–27. https://doi.org/10.1016/j.parkreldis.2020.09.005

Article  Google Scholar 

King, M., Hernandez-Castillo, C. R., Poldrack, R. A., Ivry, R. B., & Diedrichsen, J. (2019). Functional boundaries in the human cerebellum revealed by a multi-domain task battery. Nature Neuroscience, 22, 1371–1378. https://doi.org/10.1038/s41593-019-0436-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Knudsen, K., Fedorova, T. D., Hansen, A. K., Sommerauer, M., Otto, M., Svendsen, K. B., Nahimi, A., Stokholm, M. G., Pavese, N., Beier, C. P., & Brooks, D. J. (2018). In-vivo staging of pathology in REM sleep behaviour disorder: A multimodality imaging case-control study. The Lancet, 17(7), 618–628. https://doi.org/10.1016/S1474-4422(18)30162-5

Article  PubMed  Google Scholar 

Li, G., Chen, Z., Zhou, L., Zhao, A., Niu, M., Li, Y., Luo, N., Kang, W., & Liu, J. (2021). Altered structure and functional connectivity of the central autonomic network in idiopathic rapid eye movement sleep behaviour disorder. Journal of Sleep Research, 30(3). https://doi.org/10.1111/jsr.13136

Liebe, T., Kaufmann, J., Li, M., Skalej, M., Wagner, G., & Walter, M. (2020). In vivo anatomical mapping of human locus coeruleus functional connectivity at 3T MRI. Human Brain Mapping, 41(8), 2136–2151. https://doi.org/10.1002/hbm.24935

Article  PubMed  PubMed Central  Google Scholar 

Lin, Y-Q., & Chen, S-D. (2018). RBD: A red flag for cognitive impairment in Parkinson’s disease. Sleep Medicine, 44, 38–44. https://doi.org/10.1016/j.sleep.2018.01.006

Article  PubMed  Google Scholar 

Liu, J., Shuai, G., Fang, W., Zhu, Y., Chen, H., Wang, Y., Li, Q., Han, Y., Zou, D., & Cheng, O. (2021). Altered regional homogeneity and connectivity in cerebellum and visual-motor relevant cortex in Parkinson’s disease with rapid eye movement sleep behavior disorder. Sleep Medicine, 82, 125–133. https://doi.org/10.1016/j.sleep.2021.03.041

Article  PubMed  Google Scholar 

Liu, W., Shen, Y., Zhong, Y., Sun, Y., Yang, J., Zhang, W., Yan, L., Liu, W., & Yu, M. (2024). Levodopa improved different motor symptoms in patients with Parkinson’s disease by reducing the functional connectivity of specific thalamic subregions. Cns Neuroscience & Therapeutics, 30(2), e14354. https://doi.org/10.1111/cns.14354

Article  CAS  Google Scholar 

Maggi, G., Trojano, L., Barone, P., & Santangelo, G. (2021). Sleep disorders and cognitive dysfunctions in Parkinson’s disease: A meta-analytic study. Neuropsychology Review, 31, 643–682. https://doi.org/10.1007/s11065-020-09473-1

Article  PubMed  Google Scholar 

Menon, V., & D’Esposito, M. (2022). The role of PFC networks in cognitive control and executive function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 47, 90–103. https://doi.org/10.1038/s41386-021-01152-w

Article  PubMed  Google Scholar 

Muthasamy, K. A., Aravamuthan, B. R., Kringelbach, M. L., Jenkinson, N., Voets, N. L., Johansen-Berg, H., Stein, J. F., & Aziz, T. Z. (2007). Connectivity of the human pedunculopontine nucleus region and diffusion tensor imaging in surgical targeting. Case Report Journal of Neurosurgery, 107(4), 814–820. https://doi.org/10.3171/JNS-07/10/0814

Comments (0)

No login
gif