Extraction and purification, pharmacological action, synthesis and product development of salidroside: a review

Nu P. Shen Nong Ben Cao jing. Nanning: Guangxi Science and Technology Press; 2016.

Li SZ. Compendium of Materia Medica. Beijing: Huaxia Publishing House; 2007.

Cong L, Zhu JH. Discussion on the efficacy and use of Rhodiola. Track Field. 2024;6:83–4.

Song T, Yuan DGB. The Four Medical Classics. Beijing: People’s Medical Publishing House; 1984.

Editorial Committee of Flora of China, Chinese Academy of Sciences. Flora of China (Vol. 34). Beijing: Science Press; 1999.

National Pharmacopoeia Committee. Chinese Pharmacopoeia (I). Beijing: China Medical Science and Technology Press; 2020. p. 161.

National Forestry and Grassland Administration, Scientific Commission for Endangered Species of the People’s Republic of China, Appendices II of the Convention on International Trade in Endangered Species of Wild Fauna and Flora [EB/OL]. https://www.trafficchina.org/cites-cop19/cites-cop19-45.

Zhu ZP, Chen RB, Zhang L. Simple phenylpropanoids: recent advances in biological activities, biosynthetic pathways, and microbial production. Nat Prod Rep. 2024;41:6–24. https://doi.org/10.1039/d3np00012e.

Article CAS PubMed Google Scholar

Li YR. Development of a new type of Rhodiola antifatigue sports drink. Sichuan Sport Sci. 2014;33:46–8. https://doi.org/10.13932/j.cnki.sctykx.2014.05.13.

Article Google Scholar

Zhi L, Liu JW, Liang TX, Lv GZ, Zhang XX, Xu JH. Study on the effect of Rhodiola capsule on enhancing endurance and anti-fatigue of soldiers in Plateau military exercises. Med Pharm J Chin People Libera Army. 2009;21:18–20.

Chen F, Jiang N, Huang H, Chen SG, Xie MZ, Liu XM. Research progress on traditional Chinese medicine in protecting space special environmental stress damage. Chin Tradit Herb Drug. 2022;53:3811–20.

Yang MN, Zhao XM. Review on the health care effect of Rhodiola capsules cultured from Sausselia sausselata. Sci Technol Inform. 2018;16:224–6. https://doi.org/10.16661/j.cnki.1672-3791.2018.27.224.

Article Google Scholar

Sun QW. Rhodiola acanthopanax lily tea, refreshing and awake. All Thing Rural. 2018;20:47 https://doi.org/10.19433/j.cnki.1006-9119.2018.20.029.

Article Google Scholar

Schriner SE, Coskun V, Hogan SP, Nguyen CT, Lopez TE, Jafari M. Extension of drosophila lifespan by Rhodiola rosea depends on dietary carbohydrate and caloric content in a simplified diet. J Med Food. 2016;19:318–23. https://doi.org/10.1089/jmf.2015.0105.

Article CAS PubMed Google Scholar

Zhao CY, Li RDCR. Study on the processing technology of a kind of Rhodiola highland barley wine. Liquor Mak. 2021;48:81–3.

Xu LF, Cao D, Jiang F, Li M, Ning BR, Song Y, et al. The process research of salidroside. J Liaoning Univ (Nat Scie Edit). 2014;41:71–5. https://doi.org/10.16197/j.cnki.lnunse.2014.01.012.

Article CAS Google Scholar

Nie JW, Sun CX, Huang SY, Luo R, Lai WF, Wang YZ, et al. The neuroprotective effect of p-benzoyl salidroside, a derivative of salidrosideon MCAO model rats. Chin Pharmacol Bull. 2022;38:67–72.

Zhang MF, Shen YQ. Research advances in pharmacologic mechanism of kidney protection of salidroside. Anti-Infect Pharm. 2017;14:721–4. https://doi.org/10.13493/j.issn.1672-7878.2017.04-001.

Article Google Scholar

Ssaratikov AS, Krasnov EA, Chnikina LA, Duvidson LM, Sotova MI, Marina TF, et al. Rhodiolosid, a new glycoside from Rhodiola rosea and its pharmacological properties. Pharmazie. 1968;23:392–5.

CAS PubMed Google Scholar

Yang HY, Duan YK, Wei ZW, Wu YQ, Zhang CH, Wu WL, et al. Integrated physiological and metabolomic analyses reveal the differences in the fruit quality of the blueberry cultivated in three soilless substrates. Foods. 2022;24:3965. https://doi.org/10.3390/foods11243965.

Article CAS Google Scholar

Zhao YP, Li FR, Zhang JD, Chen ZY, Hu J. Callus induction from sedum hybridum and determination of salidroside in callus. Acta Bot Boreal-Occidentalia Sin. 2007;8:1679–82. https://doi.org/10.3321/j.issn:1000-4025.2007.08.029.

Article Google Scholar

Zhang LH, Song YH, Sun CH, Ren BJ, Fu DX. Determination of salidroside in the Nvzhenzi by RP-HPLC. Chin Pharm J. 2001;11:42–3. https://doi.org/10.3321/j.issn:1001-2494.2001.11.015.

Article Google Scholar

Liu GY. Optimization of salidroside extracted from Rhodiola rosea by response surface methodology. Biol Chem Eng. 2018;5:65–6.

CAS Google Scholar

Wang XF, Li Y, Song JG, Xiao W. Extraction process of Salidroside from Rhodiola rosea. J Gansu Agr Univ. 2015;6:136–42+147. https://doi.org/10.13432/j.cnki.jgsau.2015.06.024.

Article Google Scholar

Zhang LH, Wang YF, Zhang XY, Liu QY, Gao SQ, Jiao J. Optimization of enzymatic extraction process of salidroside by response surface analysis. Curr Biotechnol. 2023;3:441–8. https://doi.org/10.19586/j.2095-2341.2022.0177.

Article Google Scholar

Wang BH, Wang QY, Lu ZY, Liu JX, Dou FM. Process optimization of salidroside with cellulase auxiliary ultrasonic-assisted extraction from Rhodiola cretinii by response surface methodology. IOP Conf Ser Earth Environ Sci. 2020;598:012072. https://doi.org/10.1088/1755-1315/598/1/012072.

Article Google Scholar

Yue XW. Optimization of extraction process of active components from Rhodiola sachalinensis. Med Equip. 2016;18:113–4. https://doi.org/10.3969/j.issn.1002-2376.2016.18.090.

Article Google Scholar

Xu LL, Yang XD, Chen F, Sheng LQ, Li QL. Research progress on extraction, purification and synthesis of salidroside. China Med Her. 2017;6:53–6.

Dong Y, Lin HQ, Liao S, Lu X. Advances in enzymatic extraction of polysaccharides. Sci Technol Food Indust. 2021;42:351–8. https://doi.org/10.13386/j.issn1002-0306.2020050016.

Article CAS Google Scholar

Guo N, Zhang YT, Zhang YZ, Qiao W, Jie WG. Study on the optimization of the extraction technology of salidroside by response surface methodology. Cereal Oil. 2021;12:103–7.

Dong YQ, Gu YY. Optimization of ultrasonic assisted extraction of salidroside from the leaves of acer tegmentosum maxim. by response surface methodology. Chin J Trop Agr. 2022;4:104–9.

Wang YN. Optimization of extraction and chemical synthesis of salidroside in Rhodiola. 2020. Tianjin University of Science and Technology. https://doi.org/10.27359/d.cnki.gtqgu.2020.000297.

Liu R, Guo C, Feng M, Liu CZ. Efficient microwave-assisted extraction of salidroside from Rhodiola crenulata. SN Appl Sci. 2021;1:93 https://doi.org/10.1007/S42452-020-04055-5.

Article Google Scholar

Zhang YF, Zhou ZL, Zou L, Chi R. Imidazolium-based ionic liquids with inorganic anions in the extraction of salidroside and tyrosol from Rhodiola: The role of cations and anions on the extraction mechanism. J Mol Liq. 2019;275:136–45. https://doi.org/10.1016/j.molliq.2018.11.009.

Article CAS Google Scholar

Cheng ZS, Chen YT, Zhao GC, Hong MH. Study on the extraction technology of salidroside from the root of Rhodiola rosea L. under high pressure. J Anhui Agr Sci. 2008;19:8139–40. https://doi.org/10.13989/j.cnki.0517-6611.2008.19.137.

Article Google Scholar

Chen J, Liao GP, Zhang ZY. Optimization of ultrahigh pressure extraction for salidroside from Rhodiola crenulata by central composite design/response surface methodology. Chin J Exper Tradit Med Formulae. 2012;1:19–23. https://doi.org/10.13422/j.cnki.syfjx.2012.01.006.

Article Google Scholar

Qian YC, Liu JD, Rong WH. To measure the content of rhodioloside by TLC scanning in Rhodiola spp production in Hebei provice. Res Pract Chin Med. 2002;2:21–2. https://doi.org/10.3969/j.issn.1673-6427.2002.02.009.

Article Google Scholar

Shikov AN, Kosman VM, Flissyuk EV, Smekhova IE, Elameen A, Pozharitskaya ON, et al. Natural deep eutectic solvents for the extraction of phenyletanes and phenylpropanoids of Rhodiola rosea L. Molecules. 2020;8:1826 https://doi.org/10.3390/molecules25081826.

Article CAS Google Scholar

Wu M. Extraction, separation and purification of active components from Rhodiola. 2019. Shanghai Institute of Technology. 2019. https://doi.org/10.27801/d.cnki.gshyy.2019.000034.

Jiang MX, Liu Y, Yao SQ, Peng LY, Yu WZ, Liu YX. Study on the extraction technology of salidroside from nuzhenzi (Ligustri LucidiFructus) by alkaline hydrolysis. Guid J Tradit Chin Med Pharm. 2023;2:43–6+67. https://doi.org/10.13862/j.cn43-1446/r.2023.02.008.

Article Google Scholar

Guo JJ, Huang JM, Wang F. Increasing salidroside content from the extract of ligustrum lucidum Ait. Fruits by acid hydrolysis. Chin J Appl Environ Bio. 2013;4:723–6. https://doi.org/10.3724/SP.J.1145.2013.00723.

Article CAS Google Scholar

Feng XH. Selective separation of active components from Rhodiola rosea and tea by fractional extraction. 2022. 湖Hunan Institute of Science and Technology. https://doi.org/10.27906/d.cnki.gnghy.2022.000002.

Wang JM, Chen YH, Bao YQ, YNR A, Zhu HY, Han LQ. Comparison of ultrasonic method and smashing tissue extraction process of salidroside from Rhodiolae crenulatae radix Et Rhizoma. Chin J Vet Med. 2020;11:105–8.

Wang D, Xue J, Pang HM, Jiang Z, Wang HJ. Supercritical carbon dioxide extraction and microwave-assisted extraction of salidroside from Rhodiola sachalinensis. Chem Ind For Prod. 2011;2:105–8. https://doi.org/10.1097/IGC.0b013e31820fa168.

Article Google Scholar

Guo QF, Wang FW, Chen DH, Wang DW. Study on aqueous two-phase extraction of salidroside. J Sichuan Univ (Nat Sci Edit). 2016;2:403–8.

View original article

MEDICINAL CHEMISTRY RESEARCH

0 0 0 0 0 0 0

Comments (0)