Anastasiadi D, Venney CJ, Bernatchez L, Wellenreuther M (2021) Epigenetic inheritance and reproductive mode in plants and animals. Trends Ecol Evol 36:1124–1140
Belknap JK, Noordewier B, Lame M (1989) Genetic dissociation of multiple morphine effects among C57BL/6J, DBA/2J and C3H/HeJ inbred mouse strains. Physiol Behav 46:69–74
Belknap JK, Riggan J, Cross S, Young ER, Gallaher EJ, Crabbe JC (1998) Genetic determinants of morphine activity and thermal responses in 15 inbred mouse strains. Pharmacol Biochem Behav 59:353–360
Berglund ED, Li CY, Poffenberger G, Ayala JE, Fueger PT, Willis SE, Jewell MM, Powers AC, Wasserman DH (2008) Glucose metabolism in vivo in four commonly used inbred mouse strains. Diabetes 57:1790–1799
CAS PubMed PubMed Central Google Scholar
Bottcher B, Seeber B, Leyendecker G, Wildt L (2017) Impact of the opioid system on the reproductive axis. Fertil Steril 108:207–213
Boulos LJ, Ben Hamida S, Bailly J, Maitra M, Ehrlich AT, Gaveriaux-Ruff C, Darcq E, Kieffer BL (2020) Mu opioid receptors in the medial habenula contribute to naloxone aversion. Neuropsychopharmacology 45:247–255
Breton CV, Landon R, Kahn LG, Enlow MB, Peterson AK, Bastain T, Braun J, Comstock SS, Duarte CS, Hipwell A, Ji H, LaSalle JM, Miller RL, Musci R, Posner J, Schmidt R, Suglia SF, Tung I, Weisenberger D, Zhu Y, Fry R (2021) Exploring the evidence for epigenetic regulation of environmental influences on child health across generations. Commun Biol 4:769
PubMed PubMed Central Google Scholar
Bubier JA, He H, Philip VM, Roy T, Hernandez CM, Bernat R, Donohue KD, O’Hara BF, Chesler EJ (2020) Genetic variation regulates opioid-induced respiratory depression in mice. Sci Rep 10:14970
PubMed PubMed Central Google Scholar
Byrnes EM (2005) Transgenerational consequences of adolescent morphine exposure in female rats: effects on anxiety-like behaviors and morphine sensitization in adult offspring. Psychopharmacology 182:537–544
Byrnes EM, Rigero BA, Bridges RS (2003) Induction of maternal behavior in adult female rats following chronic morphine exposure during puberty. Dev Psychobiol 43:367–372
Byrnes JJ, Babb JA, Scanlan VF, Byrnes EM (2011) Adolescent opioid exposure in female rats: transgenerational effects on morphine analgesia and anxiety-like behavior in adult offspring. Behav Brain Res 218:200–205
Byrnes JJ, Johnson NL, Carini LM, Byrnes EM (2013) Multigenerational effects of adolescent morphine exposure on dopamine D2 receptor function. Psychopharmacology 227:263–272
CAS PubMed PubMed Central Google Scholar
Camp MC, Macpherson KP, Lederle L, Graybeal C, Gaburro S, Debrouse LM, Ihne JL, Bravo JA, O’Connor RM, Ciocchi S, Wellman CL, Luthi A, Cryan JF, Singewald N, Holmes A (2012) Genetic strain differences in learned fear inhibition associated with variation in neuroendocrine, autonomic, and amygdala dendritic phenotypes. Neuropsychopharmacology 37:1534–1547
CAS PubMed PubMed Central Google Scholar
Champagne FA (2013) Early environments, glucocorticoid receptors, and behavioral epigenetics. Behav Neurosci 127:628–636
Champagne FA, Curley JP, Keverne EB, Bateson PP (2007) Natural variations in postpartum maternal care in inbred and outbred mice. Physiol Behav 91:325–334
Chu LF, Liang DY, Li X, Sahbaie P, D’Arcy N, Liao G, Peltz G, David Clark J (2009) From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics. Pharmacogenet Genomics 19:193–205
CAS PubMed PubMed Central Google Scholar
Cunningham CL, Niehus DR, Malott DH, Prather LK (1992) Genetic differences in the rewarding and activating effects of morphine and ethanol. Psychopharmacology 107:385–393
Dockstader CL, van der Kooy D (2001) Mouse strain differences in opiate reward learning are explained by differences in anxiety, not reward or learning. J Neurosci 21:9077–9081
CAS PubMed PubMed Central Google Scholar
Donaldson R, Sun Y, Liang DY, Zheng M, Sahbaie P, Dill DL, Peltz G, Buck KJ, Clark JD (2016) The multiple PDZ domain protein Mpdz/MUPP1 regulates opioid tolerance and opioid-induced hyperalgesia. BMC Genomics 17:313
PubMed PubMed Central Google Scholar
Jacob J, Michaud G, Nicola MA, Prudhomme N (1983) Genetic differences in opioids binding sites and in antinociceptive activities of morphine and ethylketocyclazocine. Life Sci 33(Suppl 1):645–648
Johnson NL, Carini L, Schenk ME, Stewart M, Byrnes EM (2011) Adolescent opiate exposure in the female rat induces subtle alterations in maternal care and transgenerational effects on play behavior. Front Psychiatry 2:29
PubMed PubMed Central Google Scholar
Kest B, Hopkins E, Palmese CA, Adler M, Mogil JS (2002a) Genetic variation in morphine analgesic tolerance: a survey of 11 inbred mouse strains. Pharmacol Biochem Behav 73:821–828
Kest B, Palmese CA, Hopkins E, Adler M, Juni A, Mogil JS (2002b) Naloxone-precipitated withdrawal jumping in 11 inbred mouse strains: evidence for common genetic mechanisms in acute and chronic morphine physical dependence. Neuroscience 115:463–469
Koekkoek LL, van der Gun LL, Serlie MJ, la Fleur SE (2022) The Clash of Two Epidemics: the Relationship Between Opioids and Glucose Metabolism. Curr Diab Rep 22:301–310
CAS PubMed PubMed Central Google Scholar
Laing BT, Jayan A, Erbaugh LJ, Park AS, Wilson DJ, Aponte Y (2022) Regulation of body weight and food intake by AGRP neurons during opioid dependence and abstinence in mice. Front Neural Circuits 16:977642
CAS PubMed PubMed Central Google Scholar
Langhammer M, Michaelis M, Hoeflich A, Sobczak A, Schoen J, Weitzel JM (2014) High-fertility phenotypes: two outbred mouse models exhibit substantially different molecular and physiological strategies warranting improved fertility. Reproduction 147:427–433
Li X, Kshatriya D, Bello NT (2022) Weight-gain propensity and morphine withdrawal alters locomotor behavior and regional norepinephrine-related gene expression in male and female mice. Pharmacol Biochem Behav 213:173329
Liang DY, Zheng M, Sun Y, Sahbaie P, Low SA, Peltz G, Scherrer G, Flores C, Clark JD (2014) The Netrin-1 receptor DCC is a regulator of maladaptive responses to chronic morphine administration. BMC Genomics 15:345
PubMed PubMed Central Google Scholar
Metten P, Crabbe JC, Belknap JK (2009) Genetic correlates of morphine withdrawal in 14 inbred mouse strains. Drug Alcohol Depend 99:123–131
Mogil JS, Kest B, Sadowski B, Belknap JK (1996) Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay. J Pharmacol Exp Ther 276:532–544
Montgomery MK, Hallahan NL, Brown SH, Liu M, Mitchell TW, Cooney GJ, Turner N (2013) Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding. Diabetologia 56:1129–1139
Motaghinejad M, Sadeghi-Hashjin G, Koohi MK, Karimian SM (2016) Attenuation of Withdrawal Signs, Blood Cortisol, and Glucose Level with Various Dosage Regimens of Morphine after Precipitated Withdrawal Syndrome in Mice. Iran J Med Sci 41:53–58
Mucha RF, van der Kooy D, O’Shaughnessy M, Bucenieks P (1982) Drug reinforcement studied by the use of place conditioning in rat. Brain Res 243:91–105
Mucha RF, Millan MJ, Herz A (1985) Aversive properties of naloxone in non-dependent (naive) rats may involve blockade of central beta-endorphin. Psychopharmacology 86:281–285
Murphy NP, Lam HA, Maidment NT (2001) A comparison of morphine-induced locomotor activity and mesolimbic dopamine release in C57BL6, 129Sv and DBA2 mice. J Neurochem 79:626–635
Papaleo F, Contarino A (2006) Gender- and morphine dose-linked expression of spontaneous somatic opiate withdrawal in mice. Behav Brain Res 170:110–118
Comments (0)