Schneider, S., Wright, C. M. & Heuckeroth, R. O. Unexpected roles for the second brain: enteric nervous system as master regulator of bowel function. Annu. Rev. Physiol. 81, 235–259 (2019).
Fung, C. & Vanden Berghe, P. Functional circuits and signal processing in the enteric nervous system. Cell. Mol. Life Sci. 77, 4505–4522 (2020).
Article CAS PubMed PubMed Central Google Scholar
Margolis, K. G., Cryan, J. F. & Mayer, E. A. The microbiota-gut-brain axis: from motility to mood. Gastroenterology 160, 1486–1501 (2021).
Article CAS PubMed Google Scholar
Rao, M. & Gershon, M. D. Enteric nervous system development: what could possibly go wrong? Nat. Rev. Neurosci. 19, 552–565 (2018).
Article CAS PubMed PubMed Central Google Scholar
Laddach, A. et al. A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia. Nat. Commun. 14, 5904 (2023).
Article CAS PubMed PubMed Central Google Scholar
Guyer, R. A. et al. Single-cell multiome sequencing clarifies enteric glial diversity and identifies an intraganglionic population poised for neurogenesis. Cell Rep. 42, 112194 (2023).
Article CAS PubMed PubMed Central Google Scholar
Wang, H., Foong, J. P. P., Harris, N. L. & Bornstein, J. C. Enteric neuroimmune interactions coordinate intestinal responses in health and disease. Mucosal Immunol. 15, 27–39 (2022).
Article CAS PubMed Google Scholar
Viola, M. F. et al. Dedicated macrophages organize and maintain the enteric nervous system. Nature 618, 818–826 (2023).
Article CAS PubMed Google Scholar
Fan, Y. et al. hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung’s disease. Cell Stem Cell 30, 264–282.e9 (2023).
Article CAS PubMed Google Scholar
Frith, T. J. R. et al. Human axial progenitors generate trunk neural crest cells in vitro. eLife 7, e35786 (2018).
Comments (0)