Sachin Y, Anne BN, Don S. Vol 83. Chronic obstructive pulmonary disease. In: Jeffrey B.H. et al. Hazzard’s Geriatric Medicine and Gerontology. 6th Ed: McGraw Hill; 2009, p. 987–1001.

Fermont JM, Masconi KL, Jensen MT, Ferrari R, Di Lorenzo VAP, Marott JM, et al. Biomarkers and clinical outcomes in COPD: a systematic review and meta-analysis. Thorax. 2019;74(5):439–46.

Article  PubMed  Google Scholar 

Hanlon P, Lewsey J, Quint JK, Jani BD, Nicholl BI, McAllister DA, et al. Frailty in COPD: an analysis of prevalence and clinical impact using UK Biobank. BMJ Open Respir Res. 2022;9(1):e001314.

Article  PubMed  PubMed Central  Google Scholar 

Park SK, Richardson CR, Holleman RG, Larson JL. Frailty in people with COPD, using the National Health and Nutrition Evaluation Survey dataset (2003–2006). Heart Lung. 2013;42(3):163–70.

Article  PubMed  PubMed Central  Google Scholar 

Marengoni A, Vetrano DL, Manes-Gravina E, Bernabei R, Onder G, Palmer K. The relationship between COPD and frailty: a systematic review and meta-analysis of observational studies. Chest. 2018;154(1):21–40.

Article  PubMed  Google Scholar 

Kennedy CC, Novotny PJ, LeBrasseur NK, Wise RA, Sciurba FC, Benzo RP. Frailty and clinical outcomes in chronic obstructive pulmonary disease. Ann Am Thorac Soc. 2019;16(2):217–24.

Article  PubMed  PubMed Central  Google Scholar 

Maddocks M, Kon SS, Canavan JL, Jones SE, Nolan CM, Labey A, et al. Physical frailty and pulmonary rehabilitation in COPD: a prospective cohort study. Thorax. 2016;71(11):988–95.

Article  PubMed  Google Scholar 

Roberts MH, Mapel DW, Ganvir N, Dodd MA. Frailty among older individuals with and without COPD: a cohort study of prevalence and association with adverse outcomes. Int J Chron Obstruct Pulmon Dis. 2022;17:701–17.

Article  PubMed  PubMed Central  Google Scholar 

Stein BD, Bautista A, Schumock GT, Lee TA, Charbeneau JT, Lauderdale DS, et al. The validity of International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis codes for identifying patients hospitalized for COPD exacerbations. Chest. 2012;141(1):87–93.

Article  PubMed  Google Scholar 

Melo SMD, Oliveira LA, Wanderley JLF, Rocha RDA. Evaluating the extremely elderly at a pulmonary function clinic for the diagnosis of respiratory disease: frequency and technical quality of spirometry. J Bras Pneumol. 2019;45(4):e20180232.

Article  PubMed  PubMed Central  Google Scholar 

Lee WJ, Chen LK, Tang GJ, Lan TY. The impact of influenza vaccination on hospitalizations and mortality among frail older people. J Am Med Dir Assoc. 2014;15(4):256–60.

Article  PubMed  Google Scholar 

Pena FG, Theou O, Wallace L, Brothers TD, Gill TM, Gahbauer EA, et al. Comparison of alternate scoring of variables on the performance of the frailty index. BMC Geriatr. 2014;14:25.

Article  PubMed  PubMed Central  Google Scholar 

Weng SC, Chen YC, Hsu CY, Lin CS, Tarng DC, Lin SY. Impacts of heart failure and physical performance on long-term mortality in old patients with chronic kidney disease. Front Cardiovasc Med. 2021;8:680098.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guigoz Y. The Mini Nutritional Assessment (MNA) review of the literature—What does it tell us? J Nutr Health Aging. 2006;10(6):466–85; discussion 485–7.

CAS  PubMed  Google Scholar 

Saez de Asteasu ML, Martinez-Velilla N, Zambom-Ferraresi F, Casas-Herrero Á, Cadore EL, Galbete A, et al. Assessing the impact of physical exercise on cognitive function in older medical patients during acute hospitalization: Secondaiy analysis of a randomized trial. PLoS Med. 2019;16(7):e1002852.

Article  PubMed  PubMed Central  Google Scholar 

Gale NS, Albarrati AM, Munnery MM, Hubbard RE, Tal-Singer R, Cockcroft JR, et al. Frailty: a global measure of the multisystem impact of COPD. Chron Respir Dis. 2018;15(4):347–55.

Article  PubMed  PubMed Central  Google Scholar 

Zhang D, Tang W, Dou LY, Luo J, Sun Y. Four different frailty models predict health outcomes in older patients with stable chronic obstructive pulmonary disease. BMC Geriatr. 2022;22(1):57.

Article  PubMed  PubMed Central  Google Scholar 

Albarrati AM, Gale NS, Munnery MM, Reid N, Cockcroft JR, Shale DJ. The Timed Up and Go test predicts frailty in patients with COPD. NPJ Prim Care Respir Med. 2022;32(1):24.

Article  PubMed  PubMed Central  Google Scholar 

Woodruff PG, Barr RG, Bleecker E, Christenson SA, Couper D, Curtis JL, et al. Clinical significance of symptoms in smokers with preserved pulmonary function. N Engl J Med. 2016;374(19):1811–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Puhan MA, Siebeling L, Zoller M, Muggensturm P, ter Riet G. Simple functional performance tests and mortality in COPD. Eur Respir J. 2013;42(4):956–63.

Article  PubMed  PubMed Central  Google Scholar 

Holden M, Fyfe M, Poulin C, Bethune B, Church C, Hepburn P, et al. Handgrip strength in people with chronic obstructive pulmonary disease: a systematic review and meta-analysis. Phys Ther. 2021;101(6):pzab057.

Article  PubMed  Google Scholar 

Johnston KN, Potter AJ, Phillips A. Measurement properties of short lower extremity functional exercise tests in people with chronic obstructive pulmonary disease: systematic review. Phys Ther. 2017;97(9):926–43.

Article  PubMed  Google Scholar 

Kovelis D, Gomes ARS, Mazzarin C, de Miranda A, Valderramas S. Association between the results of the timed up-and-go test adjusted for disease severity and sarcopenia in patients with chronic obstructive pulmonary disease: a pilot study. Clinics (Sao Paulo). 2019;74:e930.

Article  PubMed  Google Scholar 

Birinci T, Kısa EP, Akıncı B, Kuran Aslan G, Kıyan E. The investigation of falls and balance from the perspective of activities of daily living in patients with COPD. COPD. 2021;18(2):147–56.

Article  PubMed  Google Scholar 

Janaudis-Ferreira T, Beauchamp MK, Robles PG, Goldstein RS, Brooks D. Measurement of activities of daily living in patients with COPD: a systematic review. Chest. 2014;145(2):253–71.

Article  PubMed  Google Scholar 

Witt LJ, Wroblewski KE, Pinto JM, Wang E, McClintock MK, Dale W, et al. Beyond the lung: geriatric conditions afflict community-dwelling older adults with self-reported chronic obstructive pulmonary disease. Front Med (Lausanne). 2022;9:814606.

Article  PubMed  Google Scholar 

Fragoso C, Akgün KM, Jeffery SM, et al. Vol 84. Chronic obstructive pulmonary disease. In: Jeffrey B.H. et al. Hazzard’s Geriatric Medicine and Gerontology, 7e.: McGraw Hill; 2019.

Bhatt SP, Balte PP, Schwartz JE, Cassano PA, Couper D, Jacobs DR Jr, et al. Discriminative accuracy of FEV1:FVC thresholds for COPD-related hospitalization and mortality. JAMA. 2019;321(24):2438–47.

Article  PubMed  PubMed Central  Google Scholar 

Jones PW, Quirk FH, Baveystock CM, Littlejohns P. A self-complete measure of health status for chronic airflow limitation. The St. George’s Respiratory Questionnaire. Am Rev Respir Dis. 1992;145(6):1321–7.

Article  CAS  PubMed  Google Scholar 

Kusunose M, Oga T, Nakamura S, Hasegawa Y, Nishimura K. Frailty and patient-reported outcomes in subjects with chronic obstructive pulmonary disease: are they independent entities? BMJ Open Respir Res. 2017;4(1):e000196.

Article  PubMed  PubMed Central  Google Scholar